Showing 26–50 of 200 documents
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Gemechu LL, Debusho LK
An in-depth analysis of the epidemiological patterns of TB/HIV co-infection is essential since it helps to target high-risk areas with effective control measures. The main objective of this study was to assess the spatial clustering of TB/HIV co-infection prevalence in Ethiopia f…
Weld ED, Dooley KE
…pregnant and postpartum women experience an undue burden of HIV-associated tuberculosis (TB), but data are lacking on key aspects of their complex management. Often excluded from clinical trials, they are left with limited options for HIV-TB cotreatment. This review will focus on…
Keertan Dheda, MBChB, PhD
TB kills most people with HIV in Africa. TB is out of control. Radically different approaches to deal with the disease is therefor needed. It is known that intensified case finding works in high HIV prevalence environments. However, the poor performance of conventional diagnostic…
Duffy FJ, Thompson EG, Scriba TJ, Zak DE
…d by co-infection with Mycobacterium tuberculosis (Mtb) and HIV, the leading cause of death for HIV-infected individuals. Improved characterization of Mtb/HIV coinfection as a distinct disease state may lead to better identification and treatment of affected individuals. Methods …
Vecchione MB, Eiras J, Suarez GV, Angerami MT, Marquez C, et al.
…th among infectious diseases. Human immunodeficiency virus (HIV) infection is a main predisposing factor to TB reactivation. Individuals HIV-TB co-infected develop a chronic state of inflammation associated with hypothalamic-pituitary-adrenal (HPA) axis dysregulation. This result…
Judi Chen, Weining Cao, Renfang Chen, Yong Ren, Tao Li
…34 million people living with human immunodeficiency virus (HIV) worldwide are infected with latent tuberculosis (TB). The aim of this study was to determine the rate of HIV infection in TB patients and its determinants in Wuxi City, China. TB patients attending health institutio…
Augustine Chinedu Ihim, S. Meludu, CC Onyenekwe, Arthur Ebelenna Anyabolu, Comfort N Akujiobi
…ts consisting of 120 treatment naïve active TB patients [26 HIV co infected (TB+HIV+) and 82 TB+), 12 malaria parasite co-infected (TB+MP+)], 26 latent TB infected (LTB) and 105 healthy controls. Their body mass index (BMI) was calculated. Mycobacterium tuberculosis infection was…
Mupfumi L, Mpande CAM, Reid T, Moyo S, Shin SS, et al.
…nce of host blood-based biomarkers for tuberculosis (TB) in HIV-infected patients on antiretroviral therapy (ART) has not been fully assessed. We evaluated the immune phenotype and functionality of antigen-specific T-cell responses in HIV positive (+) participants with TB (n = 12…
Wong NS, Leung CC, Chan KCW, Chan WK, Lin AWC, et al.
Latent TB infection (LTBI) in HIV patients, its treatment, and immunological recovery following highly active antiretroviral therapy (HAART) could interact and impact TB disease progression. We aim to examine the factors associated with LTBI and TB disease development among HIV p…
Birku M, Desalegn G, Kassa G, Tsegaye A, Abebe M
…e the effect of pregnancy and Human immunodeficiency virus (HIV) infection on detection performances of tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube (QFTGIT) for the diagnosis of latent tuberculosis infection (LTBI) among women living in high TB and HIV endemic sett…
Petruccioli E, Chiacchio T, Navarra A, Vanini V, Cuzzi G, et al.
Objective HIV-infection increases the risk to progress to active-tuberculosis (TB). Detection of latent TB infection (LTBI) is needed to eventually propose preventive-therapy and reduce TB reservoir. QuantiFERON-TB Plus (QFT-Plus)-test identifies LTBI. Currently, only two studies…
Hormi M, Guérin-El Khourouj V, Pommelet V, Jeljeli M, Pédron B, et al.
…ERON to assist the diagnosis of active tuberculosis (TB) in HIV-infected children are limited, especially in countries with low incidence of TB/HIV coinfection. Methods QuantiFERON results were analyzed in 63 HIV-infected children who presented to our hospital in Paris, France. S…
Richard E. Chaisson, MD, Susan Swindells, MBBS
HIV-infected people have an increased risk of developing active tuberculosis (TB). At the time the study was designed, the standard course of treatment for TB was 6 to 9 months of isoniazid (INH).This study compared the safety and effectiveness of a 4-week regimen of rifapentine …
Ribhav Gupta, D.K. Winslow, Ronit Gupta, Sten H. Vermund
…are likely at higher baseline risk of Tuberculosis (TB) and HIV. Per ICE guidelines, TB screening is mandated on intake with no routine HIV testing protocols. This study explores TB and HIV epidemiology across ICE facilities from 2019-2023. Three month sliding average of monthly …
Robert Maina, Mathew Kinyanjui, Samuel Mwalili, Duncan Kioi Gathungu
…or that is considered to contribute to Kenya’s TB burden is HIV. TB is one of the most common opportunistic infections associated with HIV, and HIV infection increases the risk of developing active TB disease in individuals with latent TB infection. Due to their compromised immun…
World Health Organization
Aliyu Evuti Haruna, Nma Bida Alhaji
…und The co-infection of Mycobacterium tuberculosis (TB) and HIV poses a major global health threat, particularly in regions with high HIV prevalence. An estimated 4.4 million people are co-infected, with TB being a leading cause of AIDS-related deaths. While over 2 billion people…
K S Himani, Deepshikha Singh, Saachi Mehta, Achal Yawalkar, Abhimanyu Awasthi, et al.
HIV and Tuberculosis (TB) are the leading global causes of death among patients with infectious diseases. They contribute significantly to morbidity around the world because of their impact on shared immune defense mechanisms. Tuberculosis is an infection that exploits the vulner…
Chacon, Alexis
HIV and Tuberculosis (TB) co-infection place an immense burden on health care systems as they act in synergy to worsen disease prognoses. TB is the most common cause of death in people living with HIV (PLWH) and in turn, HIV is the most significant risk factor for progressing fro…
Fernando R, McDowell AC, Bhavaraju R, Fraimow H, Wilson JW, et al.
…ackground Persons living with human immunodeficiency virus (HIV) are at a greater risk of developing tuberculosis (TB) compared to people without HIV and of developing complications due to the complexity of TB/HIV coinfection management. Methods During 2013-2017, the Centers for …
Kishore V. R. V. K., Hemasundar Rao M.
…as to screen the children who are household contacts of TB, HIV and TB -HIV patients and identify the children with the type of tuberculosis (Latent and symptomatic) and treat accordingly there by reducing the transmission of disease, as these children may become open cases in th…
Valeria Saraceni, MD, Richard E Chaisson, M.D., Betina Durovni, M.D.
…policy of widespread INH (Isoniazid) prophylaxis therapy in HIV-infected patients with access to antiretroviral therapy reduces the incidence of active TB disease in the HIV clinic population. Tuberculosis remains a major public health problem in Brazil. Approximately 35% of HIV…
Ling Chen, Lifan Zhang, Leidan Zhang, Liyuan Zheng, Jia Tang, et al.
…is (TB) is the leading cause of death in people living with HIV (PLWH) globally. Given the increased risk of TB infection, TB preventive therapy (TPT) is recommended for PLWH to prevent TB activation and to reduce relevant mortality. However, the implementation of TPT remains wea…
Chendi BH, Tveiten H, Snyders CI, Tonby K, Jenum S, et al.
…uberculosis (TB) disease from latent TB infection (LTBI) in HIV uninfected and infected individuals enrolled in TB low-burden countries. Design Participants with TB disease (N = 85) and LTBI (N = 150) were recruited from prospective cohorts at hospitals in Norway and Denmark. Pla…
Farias R, Couto I, Pingarilho M, Fronteira I
…ence of tuberculosis (TB) and human immunodeficiency virus (HIV). The prevalence among migrants is estimated to be higher than among non-migrants, which suggests a greater vulnerability of this population. Aim To describe the distribution of TB, HIV and HIV-TB co-infection and so…