Showing 26–50 of 129 documents
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Sharma TS, Amin S, Sapre S, Golani P, Zala S
…inical, psychosocial, and financial burden on the diseased. Pregnancy in a woman with compromised pulmonary function is a challenge for the treating obstetrician. A multidisciplinary approach involving a respiratory physician, pre-conceptional counseling, and delivery at a tertia…
Ni Luh Putu Eka Arisanti, Ni Putu Ayu Widiasari, Ni Wayan Candrawati, Ida Ayu Jasminarti Dwi Kusumawardani, Ida Bagus Ngurah, et al.
… phase treatment combinations during the first trimester of pregnancy. After we consulted with other departments, especially the obstetric department, we decided not to change her regimen. Her chief complaint before treatment was cough with white sputum and fluctuated shortness o…
Putri Indah Permata, Renny Aditya, Ruth Widhiati Raharjo Putri, Mohamad Rodi Isa, Sigit Kurniawan, et al.
…mia; intrauterine growth restriction; multidrug resistance; pregnancy; tuberculosis. Kehamilan dengan Tuberkulosis Paru Resisten Obat Ganda dan Anemia Hemolitik Autoimun yang Diperberat oleh Pertumbuhan Janin Terhambat – Laporan Kasus AbstrakPendahuluanIUGR adalah komplikasi obst…
Xuhui Liu, Lu Xia, Xiaomin Wang, Zhen Huang, Shuihua Lu
…eatment Outcomes in Multidrug-Resistant Tuberculosis During Pregnancy Get access Xuhui Liu, Xuhui Liu Department of Pulmonary Medicine, The Third People's Hospital of Shenzhen, Shenzhen, China Correspondence: X. Liu, Department of Pulmonary Medicine, 2901, Bulan Rd, Shenzhen, Chi…
Esmail A, Sabur NF, Okpechi I, Dheda K
…istant TB in special situations including HIV co-infection, pregnancy, renal disease, liver disease, diabetes, and in the critically ill.
van de Water BJ, Brooks MB, Huang CC, Trevisi L, Lecca L, et al.
Background There is limited research to guide TB treatment specifically in pregnant women and few studies have described the presentation of TB in pregnant women. We aimed to understand TB presentation and treatment outcomes in pregnant women in a low HIV burden setting. We descr…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
…rtum women [2], and poor outcomes associated with TB during pregnancy for mothers and their infants [3, 4], lack of data has prevented comprehensive inclusion of pregnant and postpartum women in guidelines and remains a critical gap in our efforts to address TB globally. Because …
Alene KA, Murray MB, van de Water BJ, Becerra MC, Atalell KA, et al.
…agement of multidrug-resistant tuberculosis (MDR-TB) during pregnancy is challenging, yet no systematic synthesis of evidence has accurately measured treatment outcomes. Objective To systematically synthesize treatment outcomes and adverse events among pregnant patients with MDR-…
Walt MV, Masuku S, Botha S, Nkwenika T, Keddy KH
…nical practice is limited. The study reviewed treatment and pregnancy outcomes and birth outcomes of their new-born in a cohort of pregnant women with DR-TB from three MDR-TB hospitals during 2010 and 2018. Design/methods Data were extracted from: TB register and patient clinic n…
Tutik Kusmiati1 , Faradila Nur Aini2
…s (MDR TB) on individualregiment bedaquiline had incidental pregnancy at the 6th month treatment. In the beginning, the patientused bedaquiline because of the intolerance of second-line injectable drug. Bedaquiline regiment was usedfor 24th week. Pregnancy occured at the 6th mont…
Marian Loveday, Emma Clarence, Sindisiwe Hlangu, Nalini Singh, Sunitha Chotoo, et al.
…ant tuberculosis (MDR/RR-TB). We report maternal treatment, pregnancy, and infant outcomes to 12 months of age in a cohort of pregnant women treated with these regimens. **METHODS:** We included pregnant women treated for MDR/RR-TB from September 2023 to January 2025 in KwaZulu-…
Amina White, D. Heather Watts, Katherine E. Smith, Grace Montepiedra, Radojka M. Savić, et al.
…e (15–44 years). Despite increased tuberculosis risk during pregnancy, optimal clinical treatment remains unclear: safety, tolerability, and pharmacokinetic data for many tuberculosis drugs are lacking, and trials of promising new tuberculosis drugs exclude pregnant women. To adv…
Alene KA, Adane AA, Jegnie A
… women. However, the impact of MDR-TB and its medication on pregnancy and perinatal outcomes has been poorly understood and inconsistently reported. Therefore, using the available literature, we aim to determine whether MDR-TB and its medications during pregnancy impact maternal …
Cornish EF, Hudson J, Sayers R, Loveday M
…ible for bedaquiline therapy. Methods Contraceptive use and pregnancy rates were audited in all female patients aged 13-50 years initiated on our MDR-TB treatment programme in 2016. We then implemented an intervention consisting of procurement of depot-medroxyprogesterone acetate…
Ogunlesi Tinuade Adetutu, Adenuga Adebunkola Modupe, Kuopniyi Opeyemi Temilola, Ogunlesi Kehinde Adedoyinsola, Akodu Samuel Olufemi
…ho was treated for multi-drug resistant TB before the index pregnancy and probably had a relapse during pregnancy. The infant presented with features of sepsis at the age of ten days, but tuberculosis was only suspected when there was no clinical response to routine antibiotic th…
Azeez A, Ndege J, Mutambayi R
…I]: 0.988-1.318) age, smoking (1.047; 95% CI: 0.892-1.229), pregnancy (1.940; 95% CI: 0.793-4.743), CD 4+ count (1.163; 95% CI: 0.993-1.361), and patients with comorbidity diseases such as diabetes, liver diseases, renal failure, hepatitis, and silicosis were all significantly as…
Loveday M, Hlangu S, Furin J
…plicated and potentially deadly disease. In terms of their "pregnancy identity" and "RR-TB patient identity" that emerged as part of their care experiences, four key themes were identified that appeared to have elements that were contradictory to one another (contradictory areas)…
Zhang F, Zhang XF, Zhou HY
… two mothers of twins), 18 (75.0%) were asymptomatic during pregnancy, and four were diagnosed with tuberculosis prenatally. The numbers of tuberculous meningitis, tuberculous encephalitis and liver TB were 17 (65.4%), five (19.2%) and four (15.4%), respectively. The main symptom…
Kelly Dooley, MD, PhD, Gary Maartens, MBChB, MMed
…um sample collection, hair sample collection, chest x-rays, pregnancy testing, electrocardiograms (ECGs), and adherence questionnaires. Participants were also asked to take part in an optional cerebrospinal fluid sampling study that entailed a lumbar puncture, to be done at week…
Kelly Dooley, MD
…ye exam, an electrocardiogram (ECG) to measure heartbeat, a pregnancy test, and a blood test. Certain behaviors and substances will be prohibited during the study, including consuming grapefruit, alcohol, or caffeine (on PK visit days); taking nutritional supplements, over-the-co…
Ben Morton, MD. MPH, MBChB
…lateral flow test (if required by UKHSA) and storage, urine pregnancy test (females only). The following blood tests will be taken: HIV test, hepatitis serology, full blood count and clotting, stored serum, blood PBMCs. BCG intradermal injection (day 0): For both parts of the s…
Maugans C, Loveday M, Hlangu S, Waitt C, Van Schalkwyk M, et al.
…es for the diagnosis, prevention and treatment of TB during pregnancy were developed. RESULTS: Best practices were developed for each of the following areas: 1) screening and diagnosis; 2) reproductive health services and family planning; 3) treatment of drug-susceptible TB; 4) t…
Mirzayev F, Viney K, Linh NN, Gonzalez-Angulo L, Gegia M, et al.
… and bedaquiline together and the use of bedaquiline during pregnancy, although formal recommendations were not made on these topics.The 2020 revision has highlighted the ongoing need for high-quality evidence and has reiterated the need for clinical trials and other research stu…
World Health Organization
…n special populations and clinical circumstances, including pregnancy, renal or hepatic impairment and central nervous system involvement. These annexes are intended to support safe, effective and patient-centred implementation of WHO-recommended DR-TB treatment regimens across d…
Graciaa DS, Schechter MC, Fetalvero KB, Cranmer LM, Kempker RR, et al.
… attention to special considerations in children and during pregnancy. Expert opinion Improvements in diagnosis and management of TB have expanded the available options for TB control. Molecular testing has enhanced the detection of TB disease, but better diagnostics are still ne…