Showing 26–50 of 200 documents
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Meredith B Brooks, Giordano Sosa Soto, Jeffrey I Campbell, Farhana Amanullah, Tapash Roy, et al.
Pediatric extrapulmonary tuberculosis (EPTB) remains under-recognized due to biological, diagnostic, and systemic barriers. This Perspective outlines pragmatic, multilevel strategies-spanning frontline clinics to national systems-to strengthen diagnosis, reporting, and visibility…
Movahedi Z, Mahmoudi S, Banar M, Pourakbari B, Aziz-Ahari A, et al.
Introduction Reductions in global tuberculosis incidence are considered as one of the End TB Strategy goal. The diagnosis of tuberculosis (TB) in children is challenging due to insufficient specimen material and the scarcity of bacilli in specimens. The purpose of this study was …
Daniel Edisha Garba, Uju Marie-Esther Dibua, Chiamaka Ukamaka Oka, Yvonne Ogechukwu Ozoadibe, Friday Attah, et al.
Urogenital tuberculosis (UGTB) is a common extrapulmonary manifestation of TB, but its diagnosis remains challenging due to nonspecific symptoms and limited diagnostic tools. Despite its significant impact on global health, it remains incompletely understood and often overlooked.…
Robert Sinurat
Tuberculosis myelitis usually impacts adult patients and is associated with tuberculous meningitis, miliary tuberculosis, or human immunodeficiency virus infection. Pediatric tuberculosis myelitis cases without any associated diseases have never been reported. The author reported…
Diwan Israr Khan, Sana Jameel
**BACKGROUND:** Tuberculosis is a common systemic bacterial infectious disease usually caused by Mycobacterium tuberculosis. In India, there are an estimated 2.1 million cases of tuberculosis, with 16% of them being new extrapulmonary tuberculosis cases. Extrapulmonary tuberculos…
N.S. Pravada, А. M. Budritskiy, V.A. Seryogina
Objectives. To assess the peculiarities of diagnosis and clinical course of tuberculosis in children and adolescents. Material and methods. Retrospective analysis of outpatient records of children and adolescents with tuberculosis in Vitebsk region during the period from 2016 to …
Hsin-Ching Kuo, Solomon Chih‐Cheng Chen, Hsin-Kai Lin, Shu-Ti Chia, Joseph-Hang Leung
…(ADA), interferon-gamma release assays (IGRA) confirmed the diagnosis of tuberculosis (TB). By using the optimal cut-off value of 39 IU/L (range: 36–40 IU/L), an elevated ascitic ADA level of 71 IU/L confirmed the diagnosis of TB peritonitis.1Lewinsohn D.M. Leonard M.K. LoBue P.A…
Li G, Cannon K, Sisniega C, Fergie J
Pediatric tuberculous meningitis (TBM) is a severe form of tuberculosis that may present in children. The current diagnostic methods may have a limited impact on initial clinical decision-making. We present three children with tuberculous meningitis who had Mycobacterium tubercul…
BHARAT BHUSHAN TRIPATHI, DEEPAK KUMAR PATEL, DEVPRIYA SHUKLA, Anurag Jain
Objective: To study the clinical profile and outcome of tuberculosis (TB) in children under 14 years of age. Methods: It is a hospital-based cross-sectional study done in a tertiary referral center in Central India from July 2017 to June 2019. After ethical approval, 80 children …
C. A. Campos Seabra, A. Silva, Raquel Duro, A. Paupério, Vítor Fagundes
…rbidities can present diagnostic challenges. Extrapulmonary tuberculosis, particularly urogenital tuberculosis, is a rare but important cause of persistent genitourinary symptoms. We describe the case of an 83-year-old female with hypertension, diabetes, chronic kidney disease, a…
Jian Zeng, Haitao Su, Jin Wang, Jiaohong Zhang, Shuihua Lu, et al.
…nvestigate the clinical features and prognostic outcomes of pediatric tuberculosis (TB) in Shenzhen. **METHODS:** This retrospective study collected demographic, clinical, laboratory, and prognostic data from pediatric patients diagnosed with TB between January 2013 and January …
González Saldaña N, Macías Parra M, Xochihua Díaz L, Palavicini Rueda M, Carmona Vargas AJ, et al.
…tic, radiological and therapeutic aspects of osteoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if the diagnosis of OATB in pediatrics is a challenge due to its insidious clinical presentation. Methods A retrospective, descriptive study of th…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
Tuberculosis (TB) is a global public health challenge, contributing significantly to morbidity and mortality worldwide. This research aims to investigate the epidemiology, clinical characteristics, diagnostic methods, and early mortality rate among pediatric patients with pulmona…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
Background Tuberculosis (TB) is a global public health challenge, contributing significantly to morbidity and mortality worldwide. This research aims to investigate the epidemiology, clinical characteristics, diagnostic methods, and early mortality rate among pediatric patients w…
Consonni F, Chiti N, Ricci S, Venturini E, Canessa C, et al.
Immune response to tuberculosis (TB) has been extensively studied in the past decades and classically involves cellular immunity. However, evidence suggests that humoral immunity may play a relevant role. Past studies regarding serum immunoglobulin (Ig) levels in TB are dated and…
Işıl Ezel Taşkın Karaçay, Tuğba Erat, Saliha Kanık Yüksek, Pınar Nalçacıoğlu, Rana Beyoğlu, et al.
To the Editors: Orbital tuberculosis (O-TB) is a rare form of extrapulmonary TB that may mimic neoplasms, inflammatory pseudotumors, or abscesses. Diagnosis relies on microbiology, PCR, histopathology and imaging. Despite challenges, outcomes are favorable with timely antitubercu…
Aditya Pawar, Niranjan Sahoo, Pawan Sharma, Nidhi Rathi
…ountries like India where the general dictum is to consider Tuberculosis as one of the differential diagnosis to any condition that is still under evaluation. Parotid Tuberculosis is a very rare entity. There are fewer than 200 cases reported in literature worldwide of Parotid gl…
Gupta S, Vats P, Jha A, Singh K, Ghosh S, et al.
…of the study was to evaluate the gingival manifestations of tuberculosis (TB) in the oral cavity in pediatric patients. Study design Four pediatric patients were enrolled in the study. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed.…
Muhammad Sidat, Gil Muvale, Mohammad Salgado, Cátia Domingos, Suraia Tane Liasse, et al.
<h3>Background</h3> Tuberculosis (TB) diagnosis is challenging in children, particularly in infants, contributing to high TB-related mortality. Up to 30% of infants with pulmonary TB have concurrent extrapulmonary disease, with findings that can frequently be detected with ultras…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
Bilal Aslam, Faiza Farooq, Shafiq Ur Rahman, Fazeela Bibi, Umama Alam, et al.
Spinal tuberculosis, also known as Pott's disease, in children is a rare manifestation of extrapulmonary tuberculosis. The nonspecific clinical features, such as chronic abdominal pain, of extrapulmonary TB or spinal TB in children tend to delay diagnosis. We present the case of …
Young Seok Seo, Ji‐Man Kang, Dong Soo Kim, Jong Gyun Ahn
… cartridge-based nucleic acid amplification assay for rapid tuberculosis diagnosis and assessment of antibiotic sensitivity. Although previous evidence supports the use of Xpert for diagnosing extrapulmonary tuberculosis (EPTB) in adults, information regarding the accuracy of Xpe…
Çay Ü, Alabaz D, Gündeşlioglu ÖÖ, Mirioglu A, Pehlivan UA
Background Skeletal tuberculosis is rarely seen among extrapulmonary tuberculosis, especially in childhood because the diagnosis may be delayed for years due to diagnostic difficulties. In this study, it was aimed to evaluate the clinical characteristics, methods used in diagnosi…
Javeria Javed, Muhammad Osama Khan, Fatima Zahra, Rashida Abbas Fakhruddin Lacewala, Maryam Aftab, et al.
**OBJECTIVE:** Abdominal tuberculosis (AbTB) is an extrapulmonary manifestation of tuberculosis (TB) that remains difficult to diagnose because its symptoms resemble many other gastrointestinal disorders. This study aimed to describe the clinical presentation, diagnostic evaluati…
Zhang Y, Tao Y
Pancreatic tuberculosis (TB) is an uncommon form of extrapulmonary TB and represents a diagnostic challenge for physicians. Pancreatic TB presents with nonspecific signs and symptoms and may mimic malignancy. However, pancreatic TB rarely occurs in children. Here, we present a ca…