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He Y, Lyon CJ, Nguyen DT, Liu C, Sha W, et al.
Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen collection techniques. However, a recently reported assay that detects Mycobacterium tuberculosis virulence factors in serum can di…
Paradkar MS, Devaleenal D B, Mvalo T, Arenivas A, Thakur KT, et al.
Background Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains unclear. There have been no antimicrobial treatment trials for pediatric TBM. Methods TBM-KIDS was a p…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
…ristics, diagnostic methods, and early mortality rate among pediatric patients with pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) who were admitted to a hospital in Syria. This retrospective cohort study was conducted at the University Children's Hospital in…
González Saldaña N, Macías Parra M, Xochihua Díaz L, Palavicini Rueda M, Carmona Vargas AJ, et al.
…steoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if the diagnosis of OATB in pediatrics is a challenge due to its insidious clinical presentation. Methods A retrospective, descriptive study of the cases of Tuberculosis (TB) in children was c…
Jian Zeng, Haitao Su, Jin Wang, Jiaohong Zhang, Shuihua Lu, et al.
…nvestigate the clinical features and prognostic outcomes of pediatric tuberculosis (TB) in Shenzhen. **METHODS:** This retrospective study collected demographic, clinical, laboratory, and prognostic data from pediatric patients diagnosed with TB between January 2013 and January …
Babak Pourakbari, Hani Rostami Rad, Maryam Sotoudeh, Reihaneh Hosseinpour Sadeghi, Shima Mahmoudi, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) remains a significant global health issue due to its diagnostic complexity and paucibacillary nature. This study aimed to evaluate the clinical, diagnostic, and immunological characteristics of pulmonary TB (PTB) and extrapulmonary TB (…
Maloney ME, Cohen B
…ence increasing in the United States from 2020 to 2021. The pediatric population is particularly vulnerable to TB. Extrapulmonary manifestations of TB include cutaneous tuberculosis (CTB). Observations There are 8 forms of CTB. Lupus vulgaris (LV) is the second most common form o…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
…ristics, diagnostic methods, and early mortality rate among pediatric patients with pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) who were admitted to a hospital in Syria. Methods This retrospective cohort study was conducted at the University Children's Hos…
Ayimen Khalid Khan, Shayan Sirat Maheen Anwar, Ashok Kumar, Anam Khan
…ntries, including Pakistan, where it is highly endemic. The pediatric population is particularly at high risk of developing CNS tuberculosis. This disease can manifest in various forms, such as tuberculous meningitis, tuberculoma, tubercular abscess, Pott's spine, and tuberculous…
Drobish I, Ramchandar N, Raabe V, Pong A, Bradley J, et al.
…ted for MTB complex OAI over a 26-year period at a tertiary pediatric center in southern California. Methods We conducted a retrospective review of children diagnosed with MTB complex OAI and cared for between 31 Dec 1992 to 31 Dec 2018 at a single tertiary care pediatric hospita…
Danielle N. Aliano, Rachel Thomson
…is study was to evaluate the epidemiology of extrapulmonary pediatric NTM infections occurring from 2000 to 2017 in Queensland, Australia. METHODS: All cases of NTM and TB are notifiable under the Queensland Public Health Act (2005) and associated regulations (2005). Data from 20…
Deepanshu Singla, Manish Agrawal, Amritesh Ranjan
…y of Co-relation between Clinical and Diagnostic profile of Pediatric Tuberculosis in a tertiary care hospital. Methods: This hospital-based observational study was conducted at the Department of Pediatrics, Muzaffarnagar Medical College and Hospital, covering a population of chi…
Rangasamy Ramanthan, M. Jayapritha
…demiological profile and diagnostic procedures in suspected pediatric TB cases at a tertiary care center in Cuddalore. Methods: A hospital-based cross-sectional study was conducted from January 2023 to June 2024, involving 200 children suspected of having TB who presented to the …
Işıl Ezel Taşkın Karaçay, Tuğba Erat, Saliha Kanık Yüksek, Pınar Nalçacıoğlu, Rana Beyoğlu, et al.
… M. bovis also affects treatment planning. We report a rare pediatric case of TB with ocular involvement, underscoring the need to consider zoonotic TB in differential diagnosis and to strengthen surveillance measures.3 A previously healthy 15-year-old male presented with a 1-yea…
Jessica Kern
…-specific, with low sensitivity to diagnostic tests amongst pediatric patients. This is partly because of its ability to mimic many other disease manifestations. This study evaluated the clinical, laboratory, and radiologic observations and treatment outcomes in pediatric patient…
Mohammad Abdul Hye, Md Shamsur Rahman, Md. Iqbal Hossain, Shuperna Ahmed
… characteristics of tubercular meningitis (TBM) patients in pediatric unit of Magura Medical College Hospital. Materials and Methods: An experimental design was conducted in pediatric unit of Magura Medical College Hospital from January 2021 to June 2024. 26 cases of tubercular m…
Minotti C, Costenaro P, Donà D, Zuliani M, Bosa L, et al.
Background The incidence of pediatric inflammatory bowel disease is increasing. tumor necrosis factor alpha inhibitors medicines improved the prognosis of affected subjects. Nonetheless, a proportion of patients do not respond or lose response to treatment. Newer biologics, like …
Lo Vecchio A, Scarano SM, Amato C, Spagnuolo MI, Bruzzese E, et al.
…tuberculosis (January 1st, 2010-December 31st, 2021) at our Pediatric Infectious Diseases Unit. Disease severity was evaluated based on: the classification proposed by Wiseman et al., smear positivity, presence of symptoms at presentation, lung cavitation, extrapulmonary disease,…
Ezgi Hasbek, Emine Kübra Dindar Demiray, Sevil Alkan, Mehmet Hüseyin Metineren
…us lymphadenitis. Although viral factors are more common in pediatric patients presenting with lymphadenopathy, tuberculosis is also an important disease to be considered in the etiology of lymphadenopathy in children. In this case report, we aimed to emphasize the importance of …
Z.I. Pіskur, L.І. Pylypiv, Olga Shvets, M.І. Sakhelashvili, O.P. Kostyk, et al.
Abstract Pediatric tuberculosis is a health problem of special significance because it is a marker for current transmission of tuberculosis in society. The research aimed at analyzing the peculiarities of detection and course of pediatric extrapulmonary tuberculosis (EPTB) taking…
Meredith B Brooks, Giordano Sosa Soto, Jeffrey I Campbell, Farhana Amanullah, Tapash Roy, et al.
Pediatric extrapulmonary tuberculosis (EPTB) remains under-recognized due to biological, diagnostic, and systemic barriers. This Perspective outlines pragmatic, multilevel strategies-spanning frontline clinics to national systems-to strengthen diagnosis, reporting, and visibility…
Grohs E, Short M, Griffin G, Sheets A, Tegarden T, et al.
… in facilities with robust TB control programs. We report a pediatric case of TB meningitis who had an adult visitor with active pulmonary TB. We identified 96 contacts from the index case. One high-risk contact had a positive follow-up TB test with no clinical symptoms. TB contr…
Napoleón González Saldaña, Mercedes Macías Parra, Eduardo Arias de la Garza, Sairy Pérez Murillo, Manuel Eugenio Narro Flores, et al.
…lture-proven cases of Tb by M. bovis from 2010 to 2019 in a pediatric tertiary-care center in Mexico. Clinical and paraclinical characteristics were compared. Results We included 22 cases of Tb by M. bovis in children younger than 18 years of age. 64 percent were men, mean age wa…
BHARAT BHUSHAN TRIPATHI, DEEPAK KUMAR PATEL, DEVPRIYA SHUKLA, Anurag Jain
…% of cases. Conclusion: It is still challenging to diagnose pediatric TB. Though newer diagnostics are now available, clinical suspicion is a valuable tool. The diagnosis of pediatric TB should thus be based on a combination of epidemiological variables, clinical suspicion, and s…
Walter Fagundes, Aisha R Ahmed, Yasmin P Silva, Paweł Łajczak, Helvécio N Feitosa Filho, et al.
…loperitoneal shunt (VPS). However, its efficacy in treating pediatric tuberculous meningitis-related hydrocephalus (TBMH) remains uncertain. The authors' review aimed to evaluate the safety and effectiveness of ETV compared to VPS. **METHODS:** The authors searched PubMed, Embas…