Showing 26–50 of 63 documents
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Vo NX, Xuan Doan TB, Kha Vo DN, Tran TK, Vo TQ
…ality of life (QOL). Our purpose is to define the status of health-related QOL for international MDR-TB and XDR-TB patients. Methods Systematic review is a good method for searching and selecting related researches and articles. As such, we have searched for and cited related art…
Francesca Saluzzo, Andrea Maurizio Cabibbe, Richard Anthony, Alexandra Aubry, Francis Drobniewski, et al.
… context-appropriate diagnostic strategies. While the World Health Organisation (WHO) provides model algorithms, these require adaptation to the European Union/European Economic Area (EU/EEA) context, a setting with low TB incidence but high resources. This viewpoint from the Eur…
Vikas Panibatla, Sharath Burugina Nagaraja, Deepa Mohan, Sreenath Menon Parambanattu Kizhakkethil, M. Sangeetha
…, and outcomes. Understanding the magnitude of these mental health issues is crucial for improving TB programs and achieving successful treatment outcomes. Materials and Methods: We conducted a systematic review and meta-analysis, to assess the prevalence of depressive and anxiet…
Gaurav Derashri, Shubhangi Nayak, Aashutosh Asati, Neera Marathe, Tulsiram Jadhav
Background and aims: The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis are greatly complicating tuberculosis (TB) control efforts in many countries. In India, in 2018, out of 2.4 million notified cases of TB, there were an estimated 66359 and 3,882 …
Dzeyie KA, Basu S, Dikid T, Bhatnagar AK, Chauhan LS, et al.
…Multidrug-resistant tuberculosis (MDR-TB) is a major public health challenge in India. It is associated with poor treatment outcomes, multiple adverse effects to treatment and involves enormous social and economic losses. The objective of the study was to ascertain the epidemiolo…
Mamta Choudhary, Mamta, Pushpa
…erculosis (MDR/XDR-TB) continues to present critical public health and individual challenges, especially in high-burden settings such as India. Despite advancements in diagnostics and therapeutics, individuals affected by MDR/XDR-TB often endure significant psychosocial, economic…
Keertan Dheda, MD PhD
…ws early detection of active tuberculosis at the peripheral health clinic level. Lack of rapid, simple and accurate diagnostic tests at this level is a major hurdle in controlling the global burden of TB. A number of promising new TB diagnostics have shown initial promise but the…
Gauri Suhas Kulkarni, Abhijit J. Telkhade, Sushama Dugad
Background: Resistance to MDR TB has additional resistance to fluoroquinolones and second line injectables it is defined as XDR-TB. The present study is designed to evaluate drug resistance patterns in such XDR patients. Aims and Objectives: To study drug resistance patterns in X…
Maria-Larisa Șoroagă
…by Mycobacterium tuberculosis, has been a persistent global health challenge for thousands of years, known historically by various names and often romanticized in 19th-century literature. Despite advancements in medical science, TB remains a significant issue, particularly in eco…
Chen Y, Chen W, Cheng Z, Chen Y, Li M, et al.
…drug-resistant TB requires effective control strategies and healthcare systems.
Olena Ivanova, Dragoș Băiceanu, Abhishek Bakuli, M. Vogel, Cristina Popa, et al.
… (30 vs 22.8), but remained significantly worse compared to healthy individuals. 52% of participants stated that TB affected their social or private life as well as their household financially at treatment start. Conclusions From the start of anti-TB treatment patients are suffer…
Usman Ali
…Mycobacterium tuberculosis (MTB), remains a critical global health challenge, claiming over one million lives annually. Despite substantial progress in reducing TB incidence in developed countries post-World War II, it persists as a major cause of mortality, particularly in low-i…
World Health Organization. Regional Office for Europe
…nclude the same targets as set by the Global Plan and World Health Assembly resolution WHA62.15, to provide universal access to diagnosis and treatment of MDR-TB. The implementation of the Consolidated Action Plan would mean that the emergence of 250 000 new MDR-TB patients and 1…
Ginenus Fekadu, Tadesse Tolossa, Tesfaye Regassa Feyissa, Sze Chai Chan, Nathorn Chaiyakunapruk, et al.
…ly drug-resistant TB (pre-XDR/XDR-TB), is a critical global health challenge. Phenotypic drug susceptibility testing (pDST), the gold standard, has prolonged turnaround times, while targeted next-generation sequencing (tNGS) rapidly identifies resistance-conferring mutations. Thi…
Xue Y, Zhou J, Wang P, Lan JH, Lian WQ, et al.
…on, marginalization, and social barriers, is a major public health problem. The assessment of TB burden and trend can provide crucial information for policy decision and planning, and help countries in the world to achieve the goal of sustainable development of ending the epidemi…
Manisha Nagpal, Sarthak Chawla, Priyanka Devgun, Naresh Chawla
…g resistant tuberculosis (MDR-TB) has become a major public health problem. It is associated with significant morbidity and mortality. The treatment success rate worldwide is around 50%.Methods: This cross-sectional study was conducted on all MDR-TB patients who were registered a…
Song WM, Li YF, Liu YX, Liu Y, Yu CB, et al.
…ially multidrug-resistant tuberculosis (MDR-TB) is a public health threat. Little is known about estimates of different profiles and rates of DR-TB among children globally. Methods: We did a systematic review and meta-analysis of observational studies reporting DR-TB among childr…
Malík I, Čižmárik J, Pecháčová M
…are subsidized by state and regional governments as well as health authorities. Each region has its own specific characteristics and needs specific interventions. Although some novel anti-tuberculosis (anti-TB) drugs (bedaquiline, delamanid) were approved by relevant authorities,…
N.A. Pavluchenkova, A.V. Mikheeva, E. A. Sakharitova
… registered at these countries and recommended by the World Health Organization for the treatment of multidrug-resistant tuberculosis and put into circulation from 2000 to 2020: linezolid, bedaquiline, delamanid, clofazimine (as of 07.2020). The data were compared with the charac…
Diel R, Sotgiu G, Andres S, Hillemann D, Maurer FP
…ethods Hospitalization costs as covered by German statutory health insurance and the loss of productivity due to illness were calculated using the most recent 2018 statistical data. Costs due to combining five agents in the intensive phase and costs of outpatient monitoring were …
Saima Abid
Antimicrobial resistance (AMR) is a growing public health threat. Resistant microorganisms (i.e. bacteria, viruses and some parasites) through genetic mutations become too strong that they become resistant to the antimicrobials (i.e. antibiotics, antivirals and antimalarial) over…
Pratik Kumar, Amardeepak Toppo, Roshan Lal, Sagarika Pradhan, Puneet Bhardwaj
Abstract Background: There is an increasing incidence of multidrug-resistant tuberculosis (TB)/preextensively drug-resistant TB (XDR TB) and XDR TB globally. Therefore, rapid diagnostic tests with good sensitivity and specificity are need of hour. Truenat Mycobacterium tuberculos…
Evans D, Hirasen K, Ramushu C, Long L, Sinanovic E, et al.
…re more expensive to both patients and providers. The World Health Organization (WHO) now recommends a new second-line 3-drug 6-month all-oral regimen consisting of bedaquiline, pretomanid, and linezolid referred to as BPaL. We estimate patient and provider costs of DR-TB treatme…
Muniyandi M, Ramesh PM, Wells WA, Alavadi U, Sahu S, et al.
…fits. Conclusion As a lower-cost intervention with improved health outcomes, the BEAT-TB India regimen is dominant when compared to the 18-month regimen.
Paleckyte A, Dissanayake O, Mpagama S, Lipman MC, McHugh TD
…is a leading cause of death from a single infectious agent. Healthcare workers (HCWs) are at increased risk of hospital-acquired TB infection due to persistent exposure to Mycobacterium tuberculosis (Mtb) in healthcare settings. The World Health Organization (WHO) has developed a…