Showing 26–50 of 200 documents
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Nadege Nziza, Wonyeong Jung, Tina Chen, Yixiang Deng, Kees L M C Franken, et al.
… to severe forms of the disease. However, whether different pediatric outcomes relate to distinct immunologic responses remains incompletely understood. Emerging data suggest that Mtb-specific humoral immune responses represent a correlate of protection against Mtb both following…
Uet Yu, Jiaming Yu, Xindan Lian, Yu Liu, Xiaodong Wang, et al.
… these patients, data on TB prophylaxis and its outcomes in pediatric HSCT recipients remain limited. **METHODS:** We conducted a retrospective study of 714 pediatric HSCT recipients at Shenzhen Children’s Hospital from January 2018 to December 2021. Patients were categor…
Hoekstra N, Anderson M, Gaensbauer J
…logy and risk factors informing current American Academy of Pediatrics (AAP) guidelines on screening for pediatric latent tuberculosis infection (LTBI) have evolved over the past decade. To improve pediatric LTBI screening efficiency, we sought to reevaluate characteristics assoc…
Bedir Demirdag T, Ozkaya Parlakay A, Aydin F, Tugcu GD, Santaflıoglu B, et al.
… who received different biologic modifying therapies in our pediatric rheumatology department and the possibility of development of tuberculosis (TB). Methodology This retrospective study was conducted in Ankara City Hospital. Pediatric patients who were treated with biologic mod…
Gaensbauer J, Gonzales B, Belknap R, Wilson ML, O'Connor ME
…uantiFERON-tuberculosis (TB) Gold (QFT)-based screening for pediatric latent TB infection (LTBI) in the Denver Health Community Health System (CHS), an urban primary-care network in the US. Study design We retrospectively analyzed all QFTs (n = 6685) performed on children aged 2-…
Rafaela Baroni Aurílio, Adriana Rodrigues Fonseca, Ana Alice Amaral Ibiapina Parente, Maria de Fátima B. Pombo March, Marta Cristine Félix Rodrigues, et al.
…an be performed. This study aims to report a case series of pediatric patients with autoimmune rheumatic diseases, diagnosed with active TB in 2019, in a tertiary referral center in Pediatric Rheumatology and Pulmonology.
Nur Sunar Yayla E, Yıldız Ç, Esmeray Şenol P, Karaçayır N, Gezgin Yıldırım D, et al.
… of this study is to analyze the adverse events observed in pediatric patients who received biological treatment. Materials and methods This retrospective observational cohort study was conducted between January 2010 and January 2022. File records of 139 patients used biological …
L. Perini, Aroldo Carvalho, Marcos Guchert, Rodrigo Marzola, Sónia Faria, et al.
Objective: Clinical and epidemiological analysis of pediatric patients with LTBI (latent tuberculosis infection). Method: Observational, descriptive, analytical and retrospective research, with data collection from medical records of patients suspected of having LTBI treated at a…
Zhang S, Li X, Chen H, Gao X, Cai Z, et al.
…d become a new biomarker for the diagnosis and treatment of pediatric systemic lupus erythematosus (SLE) patients. Methods We have analyzed the clinical data of 776 children who are underwent TB-IGRA testing in the Department of Allergy and Rheumatology of Guangzhou Women and Chi…
L. Perini, Aroldo Carvalho, Marcos Guchert, Rodrigo Marzola, Sónia Faria, et al.
OBJECTIVE: Clinical and epidemiological analysis of pediatric patients with LTBI (latent tuberculosis infection). METHOD: Observational, descriptive, analytical and retrospective research, with data collection from medical records of patients suspected of having LTBI treated at a…
James P. Stevens, Cortney R. Ballengee, Raguraj Chandradevan, Amelia B. Thompson, Bess T. Schoen, et al.
…ts negative predictive value, moreover, was 99.9%. Multiple pediatric studies with a larger number of patients positive for tuberculosis have demonstrated IGRAs to have a higher sensitivity than TST (1,2). TSTs suffer from the subjectivity of the individual interpreting the skin …
Nordholm AC, Holden IK, Hartling UB, Andersen PH, Lillbaek T, et al.
Background In Western Europe, most pediatric tuberculosis (TB) cases occur among immigrants; however, data are rarely stratified by first/second-generation immigrants and many cases may be preventable. Methods This was a nationwide study of children Results We identified 145 case…
Krunal Patel, Kinjal Patel, Pooja Gandhi, Bhavini Rathwa, Dipak M. Nakum
…ase caused by predominantly Mycobacterium tubercle bacilli. Pediatric tuberculosis is among the top 10 causes of death in children. India accounts for one fourth of the global tuberculosis burden, standing one among the thirty high TB burden countries. Hence, children in India ar…
Sayyahfar S, Mahdavi M, Seyedi Arani S, Fotovati Z
…his study aimed to compare TST and IGRA to diagnose LTBI in pediatric heart transplant candidates. Methods This cross-sectional study was performed on 50 children, who were candidates for heart transplantation, of whom 42 cases underwent heart transplantation in Shahid Rajaie Car…
Druszczynska M, Seweryn M, Wawrocki S, Pankowska A, Kulbachko A, et al.
… determine if IP-10 could be a useful diagnostic marker for pediatric tuberculosis, either alongside or as an alternative to IFN-γ. Results Both urine and QFT cultures stimulated with M.tb antigens showed significantly higher IP-10 levels in individuals with active TB or latent T…
Amir Balakhmet
…lated deaths globally, especially in low-resource settings. Pediatric immune responses to Mtb infection have been understudied, owing in large part due to diagnostic challenges in children. We examined T cell responses in a pediatric cohort of Ugandan Mtb-infected children treate…
Wiwiek Setiowulan, redi rulandani, Helmy Rachman
Pediatric drug reaction with eosinophilia and systemic symptoms (DRESS) is a life-threatening uncommon disease that can be difficult to diagnose. We present a case of a 10-year old girl with ten days of high fever during her fifth week of ATT (consisting of isoniazid, rifampicin,…
Swamy P, Duran C, Gupta A, Misra S, Fredricks K, et al.
…e community setting. The TC-MCP serves a large foreign-born pediatric population. The need for an LTBI treatment program arose when caring for this high-risk population. Implementation The TC-MCP providers collaborated with nationally recognized pediatric TB experts as well as lo…
Adrienne Katrin M. Guiang-Valerio
PV293 / #569 Case Report Poster Topic: AS18 - Pediatric SLE Introduction Systemic lupus erythematosus (SLE) is a systemic disease, which can affect multiple organ systems. Gastrointestinal (GI) involvement is rare in pediatric SLE and is under-recognized. On the other hand, gastr…
Elif Kilic Konte, Nergis Akay, Umit Gul, Kubra Ucak, Ecenur Izzete Derelioglu, et al.
…riod by documenting adverse events in patients with various pediatric rheumatic diseases. **RESEARCH DESIGN AND METHODS:** This retrospective observational study was conducted at the Pediatric Rheumatology Department of Istanbul University Cerrahpasa between 2015 and 2023. The a…
Santos JC, Silva JB, Rangel MA, Barbosa L, Carvalho I
…luate the compliance to appointments, PT and follow-up in a pediatric population after TB exposure, followed in a single TB outpatient center, and the subsequent identification of compliance determinants. Methods Retrospective analysis of all pediatric patients who underwent PT i…
Cai Q, Shen X, Li H, Yao C, Sun N, et al.
…to evaluate the diagnosis value of Mtb-specific perforin in pediatric patients with tuberculosis. Methods Diagnostic performance of perforin levels induced by 6-kDa early secreted antigen target (ESAT6) or culture filtered protein 10 (CFP10) were evaluated in eighty-six samples f…
Manresana de Micobacteriologia, SL
…oble-blind, masked, compared with placebo clinical trial in pediatric population in contact with tuberculosis with or without tuberculosis infection. This trial aims to study the effect of the probiotic Nyaditum resae® at the level of specific Treg memory cells eight weeks after …
Naglaa Ibrahim, Saad Mansour, Ehab Abd El-Hamid Abd El-Salam, Rehab Ahmed Rabie
…ntrol group. This study was conducted at Zagazig University Pediatric Hospital. All patients were subjected to the following: Full history taking, full general examination, and investigation (Tuberculin test and chest X ray). Results: In the current study, 42% were male and (58%)…
Wattal C, Raveendran R
…d some of them have been evaluated for their application in pediatric tuberculosis as well. There is an attempt to improve smear microscopy by introducing light-emitting diode (LED) fluorescence microscopy and there are also some automated digital microscopy platforms under evalu…