Showing 26–50 of 200 documents
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Park HY, Kwon JW, Kim HL, Kwon SH, Nam JH, et al.
… group) to treat newly diagnosed MDR-TB patients. Methods A health economic analysis over lifetime horizon (20 years) from the perspective of the healthcare system in Korea was conducted. We developed a combined simulation model of a decision tree model (initial two years) and tw…
Patel LN, Gurumurthy M, Bronson G, Sanders K, Rusen ID
…, community engagement, regulatory and ethics requirements, health economics, and other (respondent designated) about which a practical guide would be useful to improve future trial implementation. For each aspect of trial implementation selected, respondents were asked to report…
Chatterjee S, Das P, Vassall A
…to curb the spread of coronavirus infection had significant health and economic impacts on the Indian economy. There is limited empirical evidence on how COVID-19 restrictive measures may impact the economic welfare of specific groups of patients, e.g., tuberculosis patients. We …
Lange C, Aarnoutse RE, Alffenaar JWC, Bothamley G, Brinkmann F, et al.
…mpicin and isoniazid) represents a growing threat to public health and economic growth. Never before in the history of mankind have more patients been affected by MDR-TB than is the case today. The World Health Organization reports that MDR-TB outcomes are poor despite staggering…
Lange C, Chesov D, Heyckendorf J, Leung CC, Udwadia Z, et al.
…l pathogen worldwide, represents a growing threat to public health and economic growth. The global burden of multidrug-resistant tuberculosis (MDR-TB) has recently increased by an annual rate of more than 20%. According to the World Health Organization approximately only half of …
Peresu E, De Graeve D, Heunis JC, Kigozi NG
…ed therapy (DOT) and MDR-TB injection administration to lay health workers, to a routine clinic-based strategy within an established national TB programme in Eswatini. Methods Data on costs and effects of the two ambulatory models of MDR-TB care was collected using documentary da…
Jesus-Rodriguez Manzano, Divina Cristy D. Redondo-Samin
…TB) is one of the major diseases responsible for the public health and economic crisis in low-income countries, with the Philippines as one of the eight countries in 2020 that accounted for two thirds of the new TB cases worldwide. Its three most populous regions which are the Na…
Zhongfei Pei, Sok King Ong, Siyan Yi, Chitin Hon, Ming Xu
…access to anti-tuberculosis drugs remains a pressing global health challenge. We aim to investigate consumption trends across nine Asia-Pacific countries between 2019 and 2022. **METHODS:** We used pharmaceutical sales data from three databases to analyze 17 anti-tuberculosis dr…
Fathiyah Isbaniah, Budi Haryanto, Nabila Assakinah Lubis, Cindy Refina Maharani, Heidy Agustin, et al.
…troduction: Tuberculosis (TB) continues to pose significant health and economic challenges globally. Drug-resistant TB (DR-TB), particularly resistance to bedaquiline (BDQ), threatens the efficacy of current treatment regimens. Limited phenotypic drug susceptibility testing (DST)…
Smith I, Forse R, Sidney Annerstedt K, Thanh NT, Nguyen L, et al.
Introduction The health and economic burden of tuberculosis (TB) in urban Viet Nam is high. Social protection and support interventions can improve treatment outcomes and reduce costs. However, evidence regarding optimal strategies in this context is lacking. This study aimed to …
Jingjing Li, Huxiao Sun, Dzmitry Shcharbin, Serge Mignani, Jean-Pierre Majoral, et al.
…disease caused by(), which puts enormous pressure on public health and economic systems worldwide. Therefore, accurate diagnosis and timely intervention of TB are critical for interrupting disease transmission and reducing mortality among TB patients. However, the low bioavailabi…
Fazeela Arshad, Iram Ilyas, Najida Irfan, Khadija Yasmeen, Muhammad Asif, et al.
…obacterium tuberculosis complex (MTC), poses a major public health hazard globally, especially in developing countries.Mycobacterium bovis having 4200 genes, pathogenicity is associated with prolineglutamate or proline-proline-glutamate genes.The zoonotic nature of infection unde…
Du L, Zhang Y, Lv X, Duan Y, Shi X, et al.
…rug-resistant tuberculosis (MDR-TB) is the cause of serious health and economic burdens worldwide. The present study aimed to explore the initial and acquired drug-resistance rates among TB patients from 2012 to 2019 in Dalian, China. The effectiveness of MDR-TB prevention and co…
Nurul Dwi Andriani, Resta Dwi Yuliani
… direct). direct) such as biological, social, economic, and health system factors. The aim of this study was to estimate the risk of HIV infection, smoking and previous medication history on the incidence of MDR TB, with a meta-analysis of primary studies conducted by previous au…
Song WM, Li YF, Ma XB, Liu JY, Tao NN, et al.
…stant tuberculosis (DR-TB) has contributed to a significant health and economic burden on a global scale, especially in China. we sought to estimate epidemiological characteristics of primary DR-TB in China from 2004 to 2018. Methods Eleven thousand four hundred sixty-seven newly…
Ojule IN, Nwaike CM, Kingian BE
Background: Tuberculosis (TB) is a significant health and economic burden in our environment and consistently ranks amongst the most common disease that affects individuals whose immunity has been compromised. It is also one of the major infectious diseases that affect those livi…
Abideen Adedayo Ganiyu, Yohanna Kambai Avong, Akinwumi Akinyede, Olusoji Mayowa Ige, Osman El Tayeb, et al.
…many studies have shown causes a wide range of economic and health problems including death. Aim: The study examined the prevalence of ADRs, associated risk factors, socio-demographic association and outcomes among patients treated for MDR-TB at a comprehensive tuberculosis treat…
Nida Khan, Muhammad Ahmar Khan, Naila Muzaffar, Ahmad Ismail, Abdul Ghafoor, et al.
…iotics with reduced treatment duration are available. World Health Organization guidelines recommend the use of shorter all-oral regimens under operational research. To guide recommendations, we will compare two all-oral, short (≤ 11 months) regimens for the outcome…
Bao J, Sha W, Zhang WH, Zhang T, Muldoon K, et al.
…a has been playing an increasingly important role in global health in recent decades. Substantial progress and reform has been made in the country's health care system, but China still hosts one third of the world's diabetes mellitus (DM) patients and one fifth of the world's tub…
Gwenan M. Knight, Mario Raviǵlione, Richard G. White
… Scholar and increasing focus from the international public health community are timely. However, tuberculosis is not sufficiently emphasised in the AMR discussion at the highest decision-making level. Tuberculosis is the top infectious disease killer globally,2WHOGlobal tubercul…
Borham M, Oreiby A, El-Gedawy A, Hegazy Y, Hemedan A, et al.
…osis is a transboundary disease of high economic and public health burden worldwide. In this study, post-mortem examination of 750 cattle and buffalo in Tanta abattoir, Centre of the Nile Delta, revealed visible TB in 4% of animals and a true prevalence of 6.85% (95% CI: 5.3%-8.9…
Allué-Guardia A, Saranathan R, Chan J, Torrelles JB
…sistant strains of Mycobacterium tuberculosis poses a major health, social, and economic threat, and stresses the need to develop new therapeutic strategies. The notion of phage therapy against bacteria has been around for more than a century and, although its implementation was …
Tharun Ganapathy C, George NM, Selvamuthukumaran S, Anguraj P, Gilani A
…ycobacterium tuberculosis which has been a menace to public health and thwarting economic growth. Pulmonary tuberculosis being the most common type, extra pulmonary tuberculosis has a greater association with HIV and multidrug resistant tuberculosis. Cutaneous tuberculosis accoun…
Abavisani M, Khoshrou A, Eshaghian S, Karav S, Sahebkar A
…resistance has escalated dramatically, posing a significant health threat and economic burden. Drug repositioning, or drug repurposing, involves identifying new therapeutic applications for existing drugs, utilising their established safety profiles and pharmacological data to sw…
Himashree Bhattacharyya, Rashmi Agarwalla
…f the patients reported difficulties in reaching the proper health care facility for getting a correct diagnosis of MDR TB. Many of the patients 23 (54.7%) expressed concern over the irregular supply of drugs for MDR TB treatment. Most of the patients 38(90.4%) complained of havi…