Showing 1–25 of 200 documents
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Marimani M, Ahmad A, Stacey S, Duse A
…rate groups including healthy, multidrug-resistant (MDR) TB-HIV co-infected and HIV-1 positive individuals. Methods Ten patients with MDR TB and HIV-1 co-infection on TB and HIV therapy and a cohort comprised of 10 newly diagnosed individuals with HIV-1 infection were recruited f…
Sianturi EI, Izzah Z, Huda K, Sada EM, Perwitasari DA, et al.
Introduction human immunodeficiency virus (HIV) and tuberculosis (TB) remain global health problems and impose a substantial reduction in people´s quality of life (QoL). This study aimed to assess and compare the QoL in HIV and TB patients and factors associated with QoL between …
Tornheim JA, Dooley KE
…view In the past few years, tuberculosis (TB) has overtaken HIV as the infectious disease with the highest global mortality. Successful management of this syndemic will require improved diagnostic tests, shorter preventive therapies, and more effective treatments, particularly in…
Bentzon AK, Panteleev A, Mitsura V, Borodulina E, Skrahina A, et al.
…distinct discrepancies in delivery of tuberculosis (TB) and HIV services in eastern Europe (EE) vs. western Europe (WE). Objectives To verify the differences in TB and HIV services in EE vs. WE. Methods Twenty-three sites completed a survey in 2018 (EE, 14; WE, nine; 88% response…
Frolova OP, Butylchenko OV, Gadzhieva PG, Timofeeva MY, Basangova VA, et al.
…primary cause of mortality in human immunodeficiency virus (HIV) patients in Russia. Since the beginning of 2000, a sharp change in the HIV patients' structure, to the main known risk factors for HIV infection has taken place in Russia. The transmission of HIV through injectable …
Bastard M, Sanchez-Padilla E, du Cros P, Khamraev AK, Parpieva N, et al.
…ce of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB treatment outcomes are well published, few data on DR-TB outcomes among HIV co-infected people is availabl…
Francisco C, Lansang MA, Salvana EM, Leyritana K
Tuberculosis (TB) is common among persons living with HIV. This public health concern is aggravated by infection with multidrug-resistant organisms and adverse effects of polypharmacy. There are few published cases of multidrug-resistant tuberculosis (MDR-TB) in multidrug-resista…
Padayatchi N, Bionghi N, Osman F, Naidu N, Ndjeka N, et al.
…ot been extensively studied among patients co-infected with HIV drug-resistant tuberculosis (DR-TB). We compared treatment outcomes in DR-TB patients treated with BDQ- and linezolid (LZD) containing regimens to historic controls treated with second-line injectable-containing regi…
Chem ED, Van Hout MC, Hope V
Background Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in Sub-Saharan Africa (SSA), with recognised cases projected to increase with advancement in diagnostic technology. T…
Enane LA, Christenson JC
…-resistant infections. Global burdens of drug-resistant TB, HIV and gram-negative pathogens have a particular impact on paediatric age groups, necessitating a paediatric-focused agenda to address emerging resistance. Dedicated approaches are needed to find, successfully treat and…
Sultana ZZ, Hoque FU, Beyene J, Akhlak-Ul-Islam M, Khan MHR, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) in HIV infected individuals is a serious threat to global efforts to combat tuberculosis. Inconsistent findings on the association between HIV infection and MDR-TB were present in many studies. We aimed to review existing data …
Malabad JCM, Ang CF, Palabrica FAR, Cajucom MAM, Gloriani NG, et al.
…e infectious disease, particularly among people living with HIV (PLHIV). Molecular epidemiology provides information on prevalent genotypes of Mycobacterium tuberculosis and disease transmission dynamics, which aid in TB control. Identification of mutations that confer drug resis…
H Nyilana, K Reis, B Seepamore, R Perumal, A Wolf, et al.
… adherence support interventions for people with MDR-TB and HIV. Addressing these factors through tailored interventions is crucial to improving care engagement and challenging one-size-fits-all approaches to TB prevention.
Singh R, Fatima N, Shukla I, Shameem M
…on opportunistic infection in human immunodeficiency virus (HIV)-infected individuals. The risk of eventually developing active TB from latent TB infection (LTBI) is about 10% per year in HIV-positive patients in contrast to 10% lifetime risk in HIV-negative patients. Until recen…
Song Y, Jin Q, Qiu J, Ye D
…e emergence of multidrug-resistant tuberculosis (MDR-TB) in HIV-positive people poses a significant challenge to international efforts to eradicate tuberculosis (TB). Many studies found conflicting results when examining the correlation between HIV and MDR-TB. The purpose of the …
Rubinstein M, Makhon A, Losev Y, Valenci GZ, Gatt YE, et al.
Coinfection of HIV and multidrug-resistant tuberculosis (MDR-TB) presents significant challenges in terms of the treatment and prognosis of tuberculosis, leading to complexities in managing the disease and impacting the overall outcome for TB patients. This study presents a remar…
Zhou M, Liu S, Li Q, Wang Q, Zhu M, et al.
… of TB isolates from tuberculosis patients with and without HIV (TB-HIV patients and TBw/oHIV patients) in Chengdu, Sichuan, China. Methods Isolates from respiratory samples of TBw/oHIV patients and TB-HIV patients hospitalized between January 2014 and December 2017 were collecte…
Mukonzo J, Aklillu E, Marconi V, Schinazi RF
HIV-positive TB co-infected patients are at increased risk of multidrug-resistant (MDR)-TB compared to HIV-negative patients. Co-treatment of MDR-TB and HIV is common particularly in Sub-Saharan Africa where the co-morbidity is endemic. We discuss potential cellular metabolic pat…
Song Y, Jin Q, Qiu J, Ye D
…e emergence of multidrug-resistant tuberculosis (MDR-TB) in HIV-positive people poses a significant challenge to international efforts to eradicate tuberculosis (TB). Many studies found conflicting results when examining the correlation between HIV and MDR-TB. The purpose of the …
Spooner E, Reddy S, Ntoyanto S, Sakadavan Y, Reddy T, et al.
BACKGROUND: TB diagnosis in patients with HIV is challenging due to the lower sensitivities across tests. Molecular tests are preferred and the Xpert ® MTB/RIF assay has limitations in lower-income settings. We evaluated the performance of loop-mediated isothermal amplification (…
Hong H, Budhathoki C, Farley JE
…test in tuberculosis (TB) and human immunodeficiency virus (HIV) endemic countries in sub-Saharan Africa. However, whether HIV coinfection is associated with a higher incidence of AG-induced hearing loss during MDR-TB treatment is controversial. Objective To evaluate the impact o…
Miriam Abadie, Alexander Kay
…ug-resistant tuberculosis (DR-TB) treatment for people with HIV (PWH), including drug-drug interactions, investigational medications and host-directed therapy, as well as emerging evidence on novel treatment regimens, post-TB complications, and DR-TB medication resistance among P…
Hassan-Moosa R, Motsomi KW, Narasimmulu R, Sivro A, Naidu KK, et al.
…tcomes of three patients with human immunodeficiency virus (HIV), DR-TB and COVID-19. Case one A virologically suppressed 31-year-old man on antiretroviral therapy (ART) and multidrug-resistant (MDR)-TB treatment presented with mild COVID-19 and was hospitalised for 10 days of cl…
Bateman M, Wolf A, Chimukangara B, Brust JCM, Lessells R, et al.
…own to challenge treatment of human immunodeficiency virus (HIV)/AIDS and multidrug-resistant tuberculosis (MDR-TB). We hypothesized that adherence using electronic dose monitoring (EDM) would identify an antiretroviral therapy (ART) adherence threshold for emergent ART resistanc…
Jones AJ, Mathad JS, Dooley KE, Eke AC
Purpose of review Pregnant people living with HIV (PLWH) are at especially high risk for progression from latent tuberculosis infection (LTBI) to active tuberculosis (TB) disease. Among pregnant PLWH, concurrent TB increases the risk of complications such as preeclampsia, intraut…