Showing 151–170 of 170 documents
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Pagnoncelli M, Arosio M, Genovesi A, Napolitano G, Farina C
Latent Tuberculosis Infection (LTBI) is a state of persistent immune response to Mycobacterium tuberculosis complex antigens without clinical, radiological and microbiological signs of active disease. Effective diagnosis and preventive treatment of LTBI are crucial for tuberculos…
Sürücüoğlu S, Türel Ermertcan A, Çetinarslan T, Özkütük N
…berculin skin test (TST), which is used in the diagnosis of latent tuberculosis infection, may cause Koebner's phenomenon and false-positive results in psoriasis patients. The purpose of this study is to compare TST with QuantiFERON-TB Gold Plus (QFT-plus) test in psoriasis patie…
Lucía Madero, Iria Bastón, Eduard Brunet-Mas, Margalida Calafat, Grupo Joven de GETECCU
…ble risk of TB reactivation. Given this risk, screening for latent tuberculosis infection (LTBI) is essential in IBD patients before initiating immunosuppressive therapy. Guidelines recommend performing this screening ideally at the time of IBD diagnosis or, alternatively, before…
Jeanine Diur Yav, Armand Mutwadi, Albert Kalonji, Fiston Ilunga Mbayo, Pacifique Kanku Wa Ilunga, et al.
…ive cross-sectional study was conducted in 5 diagnostic and treatment centers between January 2020 and December 2022. Guardians of children diagnosed with TB (163/163, 100%) were recruited exhaustively through facility registers and community health workers, while health care pro…
Yap P, Tan KHX, Lim WY, Barkham T, Tan LWL, et al.
Objectives This first cross-sectional survey on latent tuberculosis infection (LTBI) in Singapore was performed by utilizing the QuantiFERON Gold In-tube (QFT-GIT) assay to collect data on the prevalence of LTBI and to identify potential risk factors associated with LTBI. Methods…
Denholm J, Baker AM, Timlin M
Background Latent tuberculosis infection (LTBI) is an asymptomatic condition that may progress to active tuberculosis (TB), sometimes decades after exposure. Most people with active TB in Australia have not had recent contact and have been unaware of their risk. Tests for LTBI ar…
Krishnamoorthy S, Kumaresan N, Zumla A
…o highlight the issues related to prevention, diagnosis and treatment of tuberculosis in renal transplant recipients. Methods The PubMed database was searched for publications and guidelines on diagnosis and management of LTBI in renal transplantation. Publications on renal allog…
Gasser N, Fritschi N, Egger JM, Ritz N, Schoch OD, et al.
… to assess the diagnostic pathways and adherence to current guidelines. Methods Retrospective observational study including children ≤16 years of age who had contact to a TB index case between January 2019 and July 2021. Analysis was stratified by age groups 0-4, 5-11, and 12-16 …
Chen YH, de Carvalho HM, Kalyoncu U, Llamado LJQ, Solano G, et al.
…re for treating a number of inflammatory diseases. However, treatment with TNF-α inhibitors carries an inherent risk of compromising the immune system, resulting in an increased susceptibility to infections and malignancies. This increased risk of infection is of particular conce…
Zellweger JP, Sotgiu G, Corradi M, Durando P
…jective a comprehensive strategy directed toward integrated latent tuberculosis infection (LTBI) management is needed. Recently it has been recognized that LTBI is not a stable condition but rather a spectrum of infections (e.g., intermittent, transient or progressive) which may …
Della Bella C, Motisi MA, Venturini E, D'Elios S, Asvestopoulou E, et al.
…) infection are required, primarily to detect patients with latent infections (LTBIs) in order to avoid their progression to active tuberculosis disease. The performance of the novel IGRA LIOFeron®TB/LTBI was evaluated in children. The originality of this test is the new MTB anti…
Kik SV, Schumacher S, Cirillo DM, Churchyard G, Boehme C, et al.
…is (TB) in the near future to allow for targeted preventive treatment beyond the current risk groups. Recently, a target product profile was developed that outlines the minimal and optimal characteristics for such an incipient TB test. We describe an evaluation framework for gene…
Xin H, Cao X, Du Y, Yan J, He R, et al.
…kers predicting the risk of active disease development from latent tuberculosis infection (LTBI) are urgently needed for precise intervention. This study aimed to identify potential circulating microRNAs (miRNAs) playing such a role in Chinese population. Based on a prospective s…
Hashash JG, Abou Fadel C, Hosni M, Hassoun L, Kanafani Z, et al.
The use of biological agents for the treatment of chronic inflammatory conditions such as inflammatory bowel diseases (IBD) has been on the rise.1,2 Current biological therapies include antitumor necrosis factor-α (anti-TNF-α), anti-interleukin-12/23, and anti-integrin agents. Be…
Alemu A, Bitew ZW, Diriba G, Seid G, Moga S, et al.
To estimate the prevalence of latent tuberculosis infection (LTBI) in chronic kidney disease (CKD) patients. This study was conducted following the PRISMA guidelines. We identified, 3694 studies from the whole search, and 59 studies were included. Each study's quality was assesse…
Alemu A, Bitew ZW, Diriba G, Seid G, Moga S, et al.
Objective To estimate the prevalence of latent tuberculosis infection (LTBI) in chronic kidney disease (CKD) patients . Methods This study was conducted following the PRISMA guidelines. We identified, 3694 studies from the whole search, and 59 studies were included. Each study's …
Rafiei N, Williams J, Mulley WR, Trauer JM, Jenkin GA, et al.
…se our findings to inform development of local and national guidelines. Methods The records of all adult patients who underwent renal transplantation at our centre from 2005 to 2014 were retrospectively reviewed to assess current screening practices, the risks for and burden of a…
Brett K, Severn M
There are 2 accepted tests for the identification of latent tuberculosis infection (LTBI), the tuberculin skin test (TST) and the interferon gamma release assay (IGRA). TST involves an intradermal injection of a purified protein derivative into the lower part of the arm and waiti…
Rebecca F Baggaley, Carys M Hooper, Luisa Silva, Zainab Lal, Paul Bird, et al.
…ssion. This systematic review summarises prevalence of HIV, latent and active tuberculosis and hepatitis B and C among UK migrants and evaluates associated risk factors. **METHODS:** PubMed/Medline, EMBASE, Web of Science and the Cochrane Library were systematically searched fro…
…tract Background Understanding barriers and facilitators to latent tuberculosis infection (LTBI) diagnosis and care is needed to successfully treat children/adolescents with LTBI in the US. We explored physicians’ perspectives on pediatric LTBI diagnosis and care, and strategies …