Showing 126–150 of 200 documents
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Jude S, Abedi AJ, Mehnaz S, Shameem M
…y healthcare providers, involves methodically searching for tuberculosis in individuals who may not seek medical attention otherwise. Active case finding provides a promising opportunity to identify additional undetected cases of tuberculosis within the community. The current stu…
Cessford RM
Tuberculosis is one of the oldest diseases still in existence today and is currently the leading cause of death by infectious disease. The understanding of tuberculosis in past populations is, however, limited by the uncertainty with which it can be diagnosed macroscopically in a…
Ez-Zari A, Farouk L, Mezzoug N, Mennane Z, Bouti K, et al.
Introduction Tuberculosis (TB) is a major public health problem in Morocco, specifically in the Tangier-Tetouan-Al-Hoceima region, which includes the city of Tetouan. Although the improvement in the epidemiological situation in Tetouan over the past two decades, this remains insu…
Mao L, Zhou XT, Li JP, Li J, Wang F, et al.
Background Although the overall incidence of tuberculosis in underdeveloped areas has increased in recent years, esophageal tuberculosis (ET) is still rare. Intestinal tuberculosis (ITB) is relatively more common, but there are few reports of ET complicated with ITB. We report a …
Kesarwani V, Singh NP, Kashyap B, Kumar A
Background To detect Mycobacterium tuberculosis on stool specimens by polymerase chain reaction (PCR) among patients with pulmonary tuberculosis. Detection of M. tuberculosis complex in sputum forms the basis of diagnosis of pulmonary tuberculosis. However, some patients tend to …
Shrestha P, Khanal H, Dahal P, Dongol P
…RIF assay (Xpert assay) as an initial confirmation test for tuberculosis (TB) has been considered to have impact as a significant decrease in number of clinically diagnosed pulmonary tuberculosis (PTB) cases than previous years. This study aims to find out the distribution profil…
Thimmanahalli Sobagaiah R, Kumari N, Bharathi Gattam D, Khazi MS
Background Tuberculosis remains a major challenge in India, with an estimated 2.69 million cases each year. Although men are more affected than women, gender differences and related factors affect awareness of tuberculosis and thus impact tuberculosis diagnosis and access to trea…
Lu G, Jiang X, Wu A, Zhou J, Liu H, et al.
The rapid diagnosis of tuberculosis (TB) is of great significance for the control and treatment of TB. However, TB remains a major healthy, social, and economic burden worldwide because of the lack of ideal diagnostic biomarkers. Mycobacterium tuberculosis (M. tuberculosis)- enco…
Ponce LC, Gallardo MJ, Marfil MJ, Petta A, Martínez Vivot M, et al.
Tuberculosis is a chronic and contagious infectious disease caused by multi-host species of the genus Mycobacterium grouped within the Mycobacterium tuberculosis complex. These pathogenic bacteria mainly affect mammals, including humans. The most recognized species is Mycobacteri…
Mtafya B, Qwaray P, John J, Sichone E, Shoo A, et al.
Background Mycobacterium tuberculosis is a category B infectious pathogen requiring level-3-containment laboratories for handling. We assessed the efficacy of heat and Guanidine thiocyanate (GTC) to inactivate M. tuberculosis prior to performance of tuberculosis Molecular Bacteri…
Chen J, Ruan Q, Shen Y, Wang S, Shao L, et al.
The Region of D eletion 2 (RD2) of Mycobacterium tuberculosis encodes reserved antigens that contribute to bacterial virulence. Among these antigens, Rv1983, Rv1986, Rv1987, and Rv1989c have been shown to be immunodominant in infected cattle; however, their diagnostic utility has…
Muflihah H, Flórido M, Lin LCW, Xia Y, Triccas JA, et al.
Tuberculosis (TB) infection affects a quarter of the global population resulting in a large burden of TB disease and mortality. The long-term control of TB requires vaccines with greater efficacy and durability than the current Mycobacterium bovis Bacille Calmette-Guérin (BCG). P…
Rao M, Valentini D, Zumla A, Maeurer M
Background New tuberculosis (TB) drug treatment regimens are urgently needed. This study evaluated the potential of the histone deacetylase inhibitors (HDIs) valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) to enhance the effects of first-line anti-TB drugs against …
Mishra A, Singh VK, Actor JK, Hunter RL, Jagannath C, et al.
…ognized for its potential role in innate resistance against tuberculosis (TB). While the GM-CSF is produced by a variety of host cells, including conventional and non-conventional T cells, macrophages, alveolar epithelial cells, the cell population that promotes GM-CSF mediated i…
Liu Y, Pertinez H, Davies GR, Gillespie SH, Coates AR, et al.
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis , remains a leading killer worldwide, and disease control is hampered by the ineffective control of persistent infections. Substitution of moxifloxacin for isoniazid or ethambutol in standard anti-TB regimens reduce…
Liu Q, Ma A, Wei L, Pang Y, Wu B, et al.
…number of high-burden countries account for the majority of tuberculosis cases worldwide. Detailed data are lacking from these regions. To explore the evolutionary history of Mycobacterium tuberculosis in China-the country with the third highest tuberculosis burden-we analysed a …
Varela-Castro L, Alvarez V, Sevilla IA, Barral M
Animal tuberculosis is a worldwide zoonotic disease caused principally by Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex (MTC). In southern Iberian Peninsula, wild reservoirs such as the wild boar, among other factors, have prevented the eradication of bo…
Nongchao Liao, Yan Zhao, Yan Long, Tian Hu, Yueming Shen
**BACKGROUND:** In clinical settings, pulmonary tuberculosis (PTB) patients were often found to have intestinal tuberculosis (ITB). The aim of this study was to construct a predictive model to evaluate the probability of intestinal tuberculosis in patients with pulmonary tubercul…
Vinuesa V, Borrás R, Briones ML, Clari MÁ, Cresencio V, et al.
…ing of respiratory specimens from patients with presumptive tuberculosis in terms of diagnostic accuracy and time to tuberculosis treatment inception in low-prevalence settings remains largely unexplored. We conducted a prospective intervention cohort study. Respiratory specimens…
Ayalew YE, Yehualashet FA, Bogale WA, Gobeza MB
Background Delay in the diagnosis and treatment of tuberculosis exacerbates the disease and clinical outcomes. It further enhances transmission of the infection in the society as well as increased the severity of the illness and raised rate of mortality. Objectives The major goal…
Sangjun Park, Chaeuk Chung, Sung Soo Jung, Sung-Soon Lee, Ki Man Lee, et al.
…crobiological cure remain incompletely defined in pulmonary tuberculosis. We aimed to determine the prevalence of persistent tuberculosis-related symptoms 6 months after treatment initiation and identify associated predisposing factors. **METHODS:** We analysed data from the pro…
Zhu XY, Li WQ, Chen Y, Wang MH, Zhang Q, et al.
Background Tuberculosis is a common infectious disease in developing countries. Tuberculosis and sarcoidosis are difficult to differentiate. We presented an adult case with increased serum sedimentation and positive tuberculosis antibody combined with multiple pulmonary nodules i…
Jing J, Zhuang H, Luo Y, Chen H, Rao Y
…he sonographic findings of the vas deferens in male genital tuberculosis.The ultrasonographic findings of the vas deferens of 19 cases of genital tuberculosis were retrospectively analyzed.According to the pathological and ultrasound findings, the ultrasonographic appearances of …
McLaughlin SE, Vora SB, Church EC, Spitters C, Thyer A, et al.
…e pregnancy outcomes due to delayed diagnosis of urogenital tuberculosis and propose a screening algorithm for patients from tuberculosis-endemic countries. Design Case report. Setting Academic medical center. Patients Two patients with delayed diagnosis of urogenital tuberculosi…
Arliny Y, Yanifitri DB, Purqan M, Fachri M
Pulmonary tuberculosis and lung cancer are public health problems, causing significant morbidity and mortality worldwide. The coexistence of the two diseases has rarely been reported while their causative association has been noticed leading to diagnosis delayed and prognosis wor…