Showing 126–150 of 200 documents
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Villar-Hernández R, Latorre I, Noguera-Julian A, Martínez-Planas A, Minguell L, et al.
…antigens. Methods We tested the NTM-IGRA in 99 samples from pediatric patients. Seventy-five were patients with lymphadenitis: 25 were NTM confirmed, 45 were of unknown etiology but compatible with mycobacterial infection and 5 had lymphadenitis caused by an etiologic agent other…
Mandalakas AM, Highsmith HY, Harris NM, Pawlicka A, Kirchner HL
… associations with key demographic variables during routine pediatric use in a low tuberculosis burden setting. Methods For pediatric samples received at Oxford Diagnostic Laboratories between 2010 and 2015, the associations between initial test outcome and demographics were esti…
Dayal R, Agarwal D, Bhatia R, Bipin C, Yadav NK, et al.
… of latent tuberculosis (TB) infection and TB disease among pediatric household contacts of adult drug resistant (MDR) and drug susceptible (DS) TB patients and to identify the risk factors for occurrence of TB infection in the contacts. Methods Pediatric household contacts (less…
Demir OF, Onal O
…udy was to discuss the effectiveness of mediastinoscopy for pediatric patients as the use of EBUS-EUS (Endobronchial Ultrasound-Endoscopic Ultrasound) has replaced mediastinoscopy for adult patients in evaluation of the mediastinal area. Methods The records of patients subject to…
Suárez-González J, Santoveña-Estévez A, Soriano M, Fariña JB
…n must contain the lowest number of excipients accepted for pediatrics and fulfill all the pharmacopeia requirements. Significance: At present, there is no adequate market dosage form available for children. There is, however, one in a prequalification phase by the World Health O…
Pace D, Pellegrino R, Dalpiaz I, Renni M, Galli L, et al.
Introduction The diagnosis of pediatric tuberculosis (TB) is challenging, due to the lower sensitivity of microbiological tests, such as culture and microscopy, compared to their performance in adult cases. Guidelines have introduced molecular tests, including GeneXpert MTB/ RIF …
Duque-Silva A, Hampole V, Cheng YN, Flood J, Barry PM
… describe the characteristics and posttreatment outcomes of pediatric patients with central nervous system (CNS) tuberculosis (TB) and to identify factors associated with poor outcome. Methods We included children aged 0 to 18 years with CNS TB reported to the California TB regis…
Buonsenso D, Pata D, Visconti E, Cirillo G, Rosella F, et al.
…hest computed tomography (CT) scan to evaluate suspected TB pediatric cases is increasing. We retrospectively reviewed records of patients aged <16 years diagnosed with active TB at the Pediatric Infectious Disease Unit of the Catholic University of the Sacred Heart to describe C…
Rebecca B, Chacko A, Verghese V, Rose W
Background Pediatric tuberculosis (TB) is often underdiagnosed with poor estimate of its true burden. Availability of Xpert MTB/RIF assay enhances diagnostic capacity of pediatric TB. Methods A 3-year retrospective review of hospital records was done for all children diagnosed wi…
Bendig DW
Sterile pyuria is a common finding in pediatric patients. Literature describing the diagnoses as well as clinical characteristics of children with sterile pyuria is lacking. This review was performed to establish an evidence-based approach to the differential diagnosis by way of …
Dilia Fontalvo-Rivera, Maria Daniels-García, Jesly Doria-Atencia, Karen Tous-Barrios, Liliana Molinares-Núñez, et al.
…y diagnostic methods for EPTB at the point of care (POC) in pediatric patients at a referral hospital. **PATIENTS AND METHOD:** Retrospective study in both male and female patients aged 0-17 years hospitalized from January 2012 to January 2022 in a pediatric referral hospital in…
Mihailov OM, Stavar Matei L, Tocu G, Ciubara A, Mihailov R
… prognostic factors associated with depressive disorders in pediatric patients diagnosed with tuberculosis through a prospective analysis. Materials and methods A prospective study was conducted on 190 pediatric patients, aged 7 to 18 years, diagnosed with tuberculosis and treate…
Zubair AB, Razzaq MT, Hashmi AW, Ali SMY, Israr MM, et al.
Background The etiologies of pancytopenia in the pediatric age group remain exceedingly ubiquitous and warrant extensive hematological and interventional investigations like bone marrow biopsy. It varies widely from benign nutritional disorders to fatal malignancies. The present …
Sharma S, Shulania A, Achra A, Jeram H, Kansra S, et al.
…eria Growth Indicator Tube (MGIT™) culture for diagnosis of pediatric pulmonary tuberculosis from gastric aspirate (GA) samples and to compare Xpert assay and ZN staining with MGIT rapid liquid culture. Materials and methods GA samples from 210 nonexpectorating children, aged bet…
Yunlian Huang, Qin Guo, Yang Wen, Qiong Liao, Chaomin Wan, et al.
…ity in plasma concentrations of first-line anti-TB drugs in pediatric patients and to investigate factors influencing drug concentrations. **METHODS:** A retrospective analysis was conducted on 110 pediatric tuberculosis (TB) patients who underwent therapeutic drug monitoring (T…
Mooss VS, Babu K
…treatment options, and visual outcomes in a large cohort of pediatric uveitis from a tertiary eye care center in South India. Methods This is a retrospective study carried out at a tertiary eye center in South India. Cases of pediatric uveitis between January 2012 and June 2022 w…
Rivera-Espinosa L, Castellanos-Carrizal C, Montes S
…lications, this phenomenon has been historically neglected. Pediatric tuberculosis has an insidious onset and quickly develops into disseminated disease and the young are at a special risk for dissemination. Some studies suggest that measures to contain adult tuberculosis are not…
Paradkar MS, Devaleenal D B, Mvalo T, Arenivas A, Thakur KT, et al.
Background Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains unclear. There have been no antimicrobial treatment trials for pediatric TBM. Methods TBM-KIDS was a p…
Vallejo BÁ, Lobo AH, García IC, Pérez TB, Mino-Leon G, et al.
…y. However, new infections continue to be recorded, and the pediatric population remains one of the most vulnerable groups in this region. The main objective of the study was to describe the clinical, epidemiological and psychosocial characteristics of new diagnoses of HIV MTCT i…
Jouego CG, Agbor VN, Noeske J, Manuel NA, Ayuk LN
…o difficulties in isolating Mycobacterium tuberculosis from pediatric specimens, management with toxic second line drugs, and practically the inexistence of contact tracing. In 2016, the World Health Organization (WHO) recommended a standardized 9-month regimen for adults and chi…
Tornheim JA, Paradkar M, Zhao H, Kulkarni V, Pradhan N, et al.
Objectives Pediatric tuberculosis (TB) remains difficult to diagnose. The plasma kynurenine to tryptophan ratio (K/T ratio) is a potential biomarker for TB diagnosis and treatment response but has not been assessed in children. Methods We performed a targeted diagnostic accuracy …
Maloney ME, Cohen B
…ence increasing in the United States from 2020 to 2021. The pediatric population is particularly vulnerable to TB. Extrapulmonary manifestations of TB include cutaneous tuberculosis (CTB). Observations There are 8 forms of CTB. Lupus vulgaris (LV) is the second most common form o…
Ayimen Khalid Khan, Shayan Sirat Maheen Anwar, Ashok Kumar, Anam Khan
…ntries, including Pakistan, where it is highly endemic. The pediatric population is particularly at high risk of developing CNS tuberculosis. This disease can manifest in various forms, such as tuberculous meningitis, tuberculoma, tubercular abscess, Pott's spine, and tuberculous…
Hoekstra N, Anderson M, Gaensbauer J
…logy and risk factors informing current American Academy of Pediatrics (AAP) guidelines on screening for pediatric latent tuberculosis infection (LTBI) have evolved over the past decade. To improve pediatric LTBI screening efficiency, we sought to reevaluate characteristics assoc…
Uet Yu, Jiaming Yu, Xindan Lian, Yu Liu, Xiaodong Wang, et al.
… these patients, data on TB prophylaxis and its outcomes in pediatric HSCT recipients remain limited. **METHODS:** We conducted a retrospective study of 714 pediatric HSCT recipients at Shenzhen Children’s Hospital from January 2018 to December 2021. Patients were categor…