Showing 126–150 of 170 documents
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Parriott A, Kahn JG, Ashki H, Readhead A, Barry PM, et al.
Objective Targeted testing and treatment of persons with latent tuberculosis infection (LTBI) is a critical component of the US tuberculosis (TB) elimination strategy. In January 2016, the California Department of Public Health issued a tool and user guide for TB risk assessment …
Khangura SD, Severn M
…he clinical utility, cost-effectiveness, and evidence-based guidelines concerning serial testing for latent tuberculosis infection (LTBI) in people with a risk of occupational exposure to TB. That report identified 2 economic evaluations and 3 evidence-based guidelines. The purpo…
…million children develop TB disease and many more present a latent form of infection. The objective of this study is to define the epidemiological trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried…
Subramanian AK, Theodoropoulos NM
These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation review the diagnosis, prevention, and management of tuberculosis in the pre- and post-transplant period. The challenges of screening for both latent and active T…
Sulis G, Carvalho ACC, Capone S, Hamada Y, Giorgetti PF, et al.
Background Although the management of latent tuberculous infection (LTBI) is a core component of the End TB Strategy, there is limited information about the status of implementation of such interventions in most African countries. Methods A web-based survey involving the 47 count…
Chattu VK, Sakhamuri S, Motilal S, Pounder LJ, Persad VK, et al.
…(TB), caused by Mycobacterium tuberculosis . About 5-10% of latent TB infections (LTBI) progress to active disease during the lifetime. Prevention of TB and treating LTBI is a critical component of the World Health Organization's (WHO) End TB Strategy. This study aims to examine …
Wilson L, Gracie L, Kidy F, Thomas GN, Nirantharakumar K, et al.
…or bias and quality using the Risk of Bias 2 tool and GRADE guidelines, respectively. We report efficacy rates and frequencies of adverse events from each included trial where available and qualitatively synthesise the findings. Results Thirteen papers representing eleven trials …
Mwaba P, Chakaya JM, Petersen E, Wejse C, Zumla A, et al.
An estimated 1.8 billion people worldwide have a latent tuberculosis infection (LTBI), with wide variations in LTBI rates across countries. LTBI can be due to infection with either drug-sensitive or drug-resistant Mycobacterium tuberculosis (Mtb) strains. Accurate data on the pre…
K S S, Saldanha PRM, Kushwah S, Prabhu AS
…be high in India. Inadequate diagnostic methods, suboptimal treatment and monitoring, and the lack of vigilant reporting system are some of the contributing factors for the failure of TB control. Objectives To know the current practices among local pediatricians regarding managem…
Lewis JH, Korkmaz SY, Rizk CA, Copeland MJ
Introduction Many of the first line medications for the treatment of active and latent M. tuberculosis are hepatoxic and cause a spectrum of anti-tuberculosis drug induced liver injury (ATLI), including acute liver failure (ALF). Despite advances in recognition of and prevention …
Cifu Xie, Pengliang Yin, Linxin Song, Zi Xiong, Liqiong Bai
…ncluding air conditioner filters and air). Individuals with latent TB infection who receive preventive immunotherapy with Mycobacterium vaccae can develop active TB. Active cases were not identified promptly after preventive treatment, leading to renewed transmission. **WHAT ARE…
Raghu S
…Most cases of TB in the elderly result from reactivation of latent TB due to immunosenescence. Major challenge in dealing with therapeutic aspects of elderly patients is recognising frailty to prevent loss of independence. Challenges facing with elderly TB are difficult to reach …
Mastorino L, Dapavo P, Trunfio M, Avallone G, Rubatto M, et al.
Psoriatic patients with latent tuberculosis infection and properly treated active tuberculosis need careful management when prescribing modern biological drugs. Although data and guidelines regarding tumour necrosis factor-α inhibitors advise caution and initiation of prophylacti…
Elewski BE, Baddley JW, Deodhar AA, Magrey M, Rich PA, et al.
…nce Approximately one-quarter of the global population have latent tuberculosis infection (LTBI), and tuberculosis (TB) is accountable for more than 1.5 million deaths annually. Methotrexate, cyclosporine, and tumor necrosis factor inhibitors may be associated with increased risk…
Karthikeyan Sundaram, Leela Kagithakara Vajravelu, Ravichandiran Velayutham, Utpal Mohan
…culosis in patients with autoimmune diseases is high due to treatment with anti-TNF-alpha therapy. **METHODS AND MATERIALS:** We analyzed the studies based on the Preferred Reporting Items and Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Methods of eligibility crite…
Giridharan P, Suseela RP, Zangpo T, Joshi RB, Cader M, et al.
…models, capacity building for improving cascade of care for latent TB infection, health system strengthening and effective risk communication were identified. Conclusion Full implementation of the TPT guidelines requires focused attention and coordinated action from all stakehold…
Jing Li, Qiuli Wu, Weixi Chen, Yanfang Wang, Shiming Xie, et al.
…ter study aimed to evaluate whether tuberculosis preventive treatment (TPT) for tuberculosis infection (TBI, previously referred to as "latent TB infection" or LTBI) is associated with improved pregnancy outcomes in infertile women undergoing in vitro fertilization and embryo tra…
Khan A, Rebhan A, Seminara D, Szerszen A
…he world. The gold standards of detection and management of latent tuberculosis infection (LTBI) have not been successful in complete eradication of the disease. Current screening modalities of TB include tuberculin skin testing (TST) and/or interferon-γ release assay (IGRA). How…
Anand A, Wagner C, Kong SS, Griffith E, Harimtepathip P, et al.
Introduction Latent tuberculosis infection (LTBI) screening with targeted treatment has been successful in eradicating tuberculosis (TB) as an endemic infection in the United States. The Centers for Disease Control and Prevention (CDC) recommends screening for high-risk patients.…
Riccardi N, Cenderello G, Borroni E, Rutigliani M, Cirillo DM
…sion TB risk-factors assessment, careful LTBI screening and treatment according to national guidelines, as well as a reduction in missed opportunity for prevention are necessary to avoid MTB related disease in fragile patients.
Abubakar I, Drobniewski F, Southern J, Sitch AJ, Jackson C, et al.
Background Tackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs) for the development of active tube…
Nathan Green, Kavina Manalan, Manabu Hayama, Marie O'Donoghue, Suranjith Seneviratne, et al.
… The 2016 National Institute for Health and Care Excellence guidelines recommended the tuberculin skin test (TST), at a 5-mm induration size cut-off, for the diagnosis of latent tuberculosis infection (LTBI) among adult close contacts of active tuberculosis (TB) cases. This study…
Mark Kosenko, Lilit Davtian, Ekaterina Iakovleva, Mukhammad Ashurov, Dmitrii Podgalo, et al.
…) versus shorter rifamycin-containing regimens for treating latent tuberculosis infection (TBI) in children. **METHODS:** We systematically searched MEDLINE, Embase, and Cochrane Central Register of Controlled Trials to June 2025 for randomized, controlled trials (RCTs) and coho…
Ghayumi SMA, Shamsaeefar A, Motazedian N, Mashhadiagha A, Sayadi M, et al.
…ackground Liver transplantation (LT) is considered the only treatment for patients with end-stage liver disease and, despite its incredible impacts on the patients' health status, places them in an immunocompromised state in which opportunistic infection would find a way to prese…
Lee S, Lee W, Kang SK
…ed Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The inclusion criteria were: (1) study participants working in a health care facility; (2) TB cases diagnosed by medical professionals; (3) original research articles; and (4) English reports in a peer-review…