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Aung ZZ, Saw YM, Saw TN, Oo N, Aye HNN, et al.
…f the countries with the highest burden of tuberculosis and HIV infections (TB-HIV) in the world. However, the survival rate and risk factors for mortality among TB-HIV co-infected patients in the country remain unstudied. Therefore, the purpose of this study was to examine these…
Jadhav M, Khan T, Bhavsar C, Momin M, Omri A
…Mycobacterium tuberculosis is the leading cause of death in HIV positive patients. In 2017, about 0.3 million HIV positive people died of tuberculosis. There is high load of mycobacteria and HIV in the lungs and eradication of the same is vital for patient survival. Areas covered…
Moskaliuk VD, Kolotylo TR, Pudiak KI, Rudan IV, Goliar OI, et al.
Introduction Epidemics of such dangerous diseases as HIV infection and tuberculosis continue to develop annually. Tuberculosis has become the main cause of mortality in AIDS patients. Both diseases have a negative effect on the state of the immune system, affecting the cells of t…
Ross JM, Henry NJ, Dwyer-Lindgren LA, de Paula Lobo A, Marinho de Souza F, et al.
Background Brazil has high burdens of tuberculosis (TB) and HIV, as previously estimated for the 26 states and the Federal District, as well as high levels of inequality in social and health indicators. We improved the geographic detail of burden estimation by modelling deaths du…
Catherine Keiko Gunawan, Anton Sumarpo, Agnes Rengga Indrati
…ysregulation is a hallmark of human immunodeficiency virus (HIV) infection, characterized by persistent immune activation and systemic inflammation that drive T cell exhaustion and senescence, contributing to disease progression and non-AIDS comorbidities, most notably tuberculos…
Aklillu E, Zumla A, Habtewold A, Amogne W, Makonnen E, et al.
Background and purpose In TB-HIV co-infection, prompt initiation of TB therapy is recommended but anti-retroviral treatment (ART) is often delayed due to potential drug-drug interactions between rifampicin and efavirenz. In a longitudinal cohort study, we evaluated the effects of…
Olsson O, Tesfaye F, Søkilde R, Mazurek J, Abebe M, et al.
HIV infection affects the course of tuberculosis (TB), and HIV and Mycobacterium tuberculosis (Mtb) synergize in disease progression through complex immunological interplay. To gain further understanding of these mechanisms, we compared the microRNA (miRNA) and small nucleolar RN…
Semá Baltazar C, DeLima YV, Ricardo H, Botão C, Chitsondzo Langa D, et al.
…d As part of ongoing efforts to generate evidence needed on HIV and tuberculosis (TB) to inform policies and programs aimed to improve the health outcomes of migrants and communities affected by migration and mining, a preliminary investigation was conducted through a biological …
Musaazi J, Sekaggya-Wiltshire C, Kiragga AN, Kalule I, Reynolds SJ, et al.
…ne tuberculosis (TB) treatment outcomes from a long-term TB-HIV (human immunodeficiency virus) integrated model of care at the Infectious Diseases Institute Clinic, Kampala, Uganda. METHODS We included HIV-positive adults who were new TB cases initiated on anti-tuberculosis treat…
Wondie WT, Wubneh CA, Legesse BT, Mekonen GB, Zemariam AB, et al.
Background HIV-TB co-infection poses a significant public health threat, notably in sub-Saharan Africa including Ethiopia. Despite this public health problem, studies in Ethiopia regarding the mortality of HIV-TB co-infection patients have been inconsistent, and the overall estim…
Nakiyingi L, Bwanika JM, Ssengooba W, Mubiru F, Nakanjako D, et al.
…s, utility of CXR in diagnosis of smear-negative TB in high HIV/TB burden settings in the Xpert MTB/RIF era remains unpredictable. We evaluated accuracy and additive value of CXR to Xpert MTB/RIF in the diagnosis of TB among HIV-positive smear-negative presumptive TB patients. Me…
Sianturi EI, Izzah Z, Huda K, Sada EM, Perwitasari DA, et al.
Introduction human immunodeficiency virus (HIV) and tuberculosis (TB) remain global health problems and impose a substantial reduction in people´s quality of life (QoL). This study aimed to assess and compare the QoL in HIV and TB patients and factors associated with QoL between …
Tiewsoh JBA, Antony B, Boloor R
…portunistic infection (OI) in human immunodeficiency virus (HIV) infected individuals with 0.3 million deaths in 2017. When HIV and TB co-infection occurs, they form a deadly combination with each accelerating the progression of the other, resulting in increased morbidity and mor…
Abdullahi SA, Smelyanskaya M, John S, Adamu HI, Ubochioma E, et al.
… facilities. Infectious diseases like tuberculosis (TB) and HIV are especially difficult to address under such conditions, and IDPs are vulnerable to both. Although international investment supports some health interventions among IDPs, locally sourced solutions are lacking. Meth…
Shaukat SN, Nasir F, Raza A, Khanani R, Uddin S, et al.
…formed on KIR3DS1/L1 in association with IFN-ɣ/IL-10 in TB, HIV-1, and their confections. We aimed to evaluate KIR3DS1/KIR3DL1 expression in association with IFNɣ/IL-10 in HIV-1 and TB mono-infections and HIV-1/TB confection and compared with uninfected controls using RTq PCR. We…
Mangochi P, Bossard C, Catacutan C, Van Laeken D, Kwitonda C, et al.
BACKGROUND Incarcerated individuals, especially in high HIV and TB burden settings, are at increased risk of latent TB infection and/or TB disease. We implemented a comprehensive HIV-TB intervention in a Malawi prison and studied its feasibility. METHODS Between February and Dece…
Maji D, Agarwal U, Kumar L, V V, Sharma A
The risk of death in HIV-TB coinfected individuals is far greater than in HIV-only patients. It is critical to provide timely and appropriate therapy in HIV-TB coinfected patients in order to reduce morbidity and mortality. The purpose of this study was to evaluate the clinical p…
Navasardyan I, Miwalian R, Petrosyan A, Yeganyan S, Venketaraman V
The co-occurrence of human immunodeficiency virus (HIV) and tuberculosis (TB) infection poses a significant global health challenge. Treatment of HIV and TB co-infection often necessitates combination therapy involving antiretroviral therapy (ART) for HIV and anti-TB medications,…
Thekkur P, Takarinda KC, Timire C, Sandy C, Apollo T, et al.
…D-19 was declared a pandemic, there was concern that TB and HIV services in Zimbabwe would be severely affected. We set up real-time monthly surveillance of TB and HIV activities in 10 health facilities in Harare to capture trends in TB case detection, TB treatment outcomes and H…
Gemechu LL, Debusho LK
An in-depth analysis of the epidemiological patterns of TB/HIV co-infection is essential since it helps to target high-risk areas with effective control measures. The main objective of this study was to assess the spatial clustering of TB/HIV co-infection prevalence in Ethiopia f…
Morgan PA, Parbie PK, Ntiamoah DO, Boadu AA, Asare P, et al.
…e of tuberculosis (TB) cases with diabetes mellitus (DM) or HIV comorbidities before anti-TB therapy and after the intensive phase anti-TB therapy. Methods Ninety cases comprising 60 TB-only, 23 TB-DM, 7 TB-HIV were recruited, among which 35 TB-only, 10 TB-DM, 5 TB-HIV were also …
Weld ED, Dooley KE
…pregnant and postpartum women experience an undue burden of HIV-associated tuberculosis (TB), but data are lacking on key aspects of their complex management. Often excluded from clinical trials, they are left with limited options for HIV-TB cotreatment. This review will focus on…
Boffa J, Moyo S, Chikovore J, Salomon A, Daniels B, et al.
…d South Africa has high burdens of tuberculosis (TB) and TB-HIV, yet the quality of patient care in the private sector is unknown. We describe quality of TB and TB-HIV care among private general practitioners (GPs) in two South African cities using standardised patients (SPs). Me…
Aturinde A, Farnaghi M, Pilesjö P, Mansourian A
…for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to the active status. In order to manage this double epidemic situation, an integrated approach that includes HIV managemen…
Pourakbari B, Mamishi S, Banar M, Keshtkar AA, Mahmoudi S
Introduction Co-infection of TB/ HIV is an emerging threat to a global public health. Although several studies have investigated the prevalence of TB/HIV co-infection in Iran, the results are inconsistent. The current systematic review and meta-analysis was planned to estimate th…