Showing 101–125 of 200 documents
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Ekaterina V Kurbatova, William C Whitworth, Kia E Bryant, Meredith G Dixon, Kelly E Dooley, et al.
…) treatment compared with the standard regimen. We analyzed pregnancy outcomes of women who became pregnant during the study. Among 740 women, 97 (13.1%) became pregnant. Of 102 pregnancies (in 97 participants), 30 (29.4%) participants were exposed to study drugs. Fetal loss…
Hughes JA, Pinilla M, Brooks KM, Eke AC, Stek A, et al.
…quinolones, but data on long-term exposure during and after pregnancy are limited. We examined the pharmacokinetics and safety of levofloxacin in an observational cohort of pregnant and postpartum women receiving treatment for RR-TB. Methods Participants were enrolled in their se…
Pop LG, Bacalbasa N, Suciu ID, Ionescu P, Toader OD
Tuberculosis (TB) in pregnancy is not only a matter of the past; it is also a current problem. These days, TB appears through mass migration and tourism in countries where it was believed that this condition is eradicated. Adequate knowledge about the medical history of patients,…
Sharon Sawe, Lufina Tsirizani, Richard Court, Kamunkhwala Gausi, Asanda Poswa, et al.
…is (RR-TB). There are limited data describing the effect of pregnancy on the pharmacokinetics of levofloxacin. We aimed to characterize the pharmacokinetics of levofloxacin in adults with RR-TB, including the effect of pregnancy. We pooled data from two studies conducted in adult…
Nachega JB, Sam-Agudu NA, Budhram S, Taha TE, Vannevel V, et al.
… of data on SARS-CoV-2 infection and associated COVID-19 in pregnancy. Given the endemicity of infections such as malaria, HIV, and tuberculosis (TB) in sub-Saharan Africa (SSA), it is important to evaluate coinfections with SARS-CoV-2 and their impact on maternal/infant outcomes…
Daniela Vinueza, David E Rebellón-Sánchez, Maria Alejandra Recio, Ana Maria Granados, Luis Alberto Escobar, et al.
…sents the case of a 22-year-old woman at 29 weeks of pregnancy, who exhibited recent onset neurologic symptoms including paresthesia of the right side of the face, involuntary myoclonic movements in the ipsilateral hand, 1 week of weakness in the right side of the b…
Alene KA, Jegnie A, Adane AA
… to examine the impact of MDR-TB and its medications during pregnancy on maternal and perinatal outcomes. Search strategy PubMed, Scopus and Web of Science databases were searched from earliest to February 2020. Selection criteria Records were screened based on pre-defined select…
Curcio AM, Shekhawat P, Reynolds AS, Thakur KT
Neurologic infections during pregnancy represent a significant cause of maternal and fetal morbidity and mortality. Immunologic alterations during pregnancy increase the susceptibility of the premature brain to damage. This chapter summarizes the epidemiology, pathophysiology, an…
Shiu JR, Min A, Kiang TKL
…able data on the use of anti-tuberculosis (TB) drugs during pregnancy, with a focus on treatment outcomes, safety, and pharmacokinetics. This qualitative, narrative review was based on literature searches in Medline, Pubmed, Embase, and Google Scholar (from their inception to 13 …
Song Y, Wang Z, Hao Z, Li L, Lu J, et al.
… is a rare severe clinical syndrome. HLH manifesting during pregnancy has been paid much attention in recent years. Despite the specificity of pregnancy-related HLH, there has not been any consensus regarding its treatment. According to a previous study, corticosteroid/IVIG is th…
Alajaji NM, Sallout B, Baradwan S
…nosed with tuberculous spondylitis, or Pott disease, during pregnancy. CASE REPORT A 27-year-old female, in her first pregnancy and at 29 weeks of gestation, presented to the Emergency Department with worsening severe neck and back pain for the past 5 months. Post-gadolinium cont…
Felix Bongomin, Phillip Ssekamatte, Ronald Olum, Diana Sitenda, Davis Kibirige, et al.
**BACKGROUND:** Pregnancy modulates immune responses against() infection. Cytokines, including interleukin-2 (IL-2), play a crucial role incontainment, mainly by inducing the proliferation of T cells. However, the role of IL-2 in latent tuberculosis (TB) infection (LTBI) screenin…
Stroeken Y, Broekhuijsen K, Leyten E, Hermes W
… tube and endometrial pathology leading to subfertility and pregnancy loss. This case report describes a 34-year-old woman from Ivory Coast who was diagnosed with intrauterine tuberculosis after hysteroscopic evacuation of suspected retained placental tissue following an immature…
Kuupiel D, Tlou B, Bawontuo V, Mashamba-Thompson TP
…mentation. This study assessed the current accessibility of pregnancy-related point-of-care (POC) diagnostic tests for maternal healthcare in rural primary healthcare (PHC) clinics in northern Ghana. Method We randomly selected 100 PHC clinics providing maternal healthcare from a…
Yadav A, Singh A, Aggarwal K
Acute paraplegia in pregnancy is uncommon but can result from pathology including Guillain-Barre syndrome, acute transverse myelitis, and spinal tuberculosis, also known as Pott's disease of the spine. India has a high incidence of tuberculosis (2.8 million cases annually) theref…
Zhuang L, Wang XY, Sang Y, Xu J, He XL
Background Acute urinary retention (AUR) is rare during pregnancy. Case summary We report on three pregnant women with AUR between the 10 th and 18 th wk of gestation. Case 1 was first diagnosed as urinary tract infection and developed a urinary tract infection due to urinary ret…
McLaughlin SE, Vora SB, Church EC, Spitters C, Thyer A, et al.
Objective To report 2 cases of adverse pregnancy outcomes due to delayed diagnosis of urogenital tuberculosis and propose a screening algorithm for patients from tuberculosis-endemic countries. Design Case report. Setting Academic medical center. Patients Two patients with delaye…
Afsana Rahman Maliha, Md Mostakim Billah, Md Mortuza Arafin, Ibrahim Khalil, Tahseen Tabassum
Spinal tuberculosis (Pott's disease) during pregnancy is rare and poses diagnostic challenges due to overlapping symptoms with pregnancy-related changes, potentially leading to severe neurological deficits if untreated. We report an 18-year-old primigravida at 32 weeks gestation …
Waleed Razzaq Chaudhry, Sana Altaf, Cara Mohammed, Sofia Fuerte
Tuberculosis (TB) during pregnancy can cause certain deleterious effects to both the mother and the fetus, leading to significant morbidity and mortality. The risk of TB rises significantly during pregnancy due to dampening of the immune response in females and certain factors ye…
Sujithra Devi R, Priya S, Kumari M, Ramkumar G, Jinkala S, et al.
…prevalence of tuberculosis. This is rarely diagnosed during pregnancy. The presentation can mimic other etiologies such as eclampsia or cerebral venous sinus thrombosis so the diagnosis can be challenging, particularly when presenting with seizures in pregnancy. Described here is…
Srivastava S, Raj A, Agarwal R, Bhosale S, Marathe N
…is of the spine causing paraplegia in the 2 nd trimester of pregnancy is rare and poses significant management dilemmas. Pregnancy, a relatively immunocompromised state with high hormonal levels, may prompt rapid TB destruction of a vertebral body resulting in an acute/ profound …
Tiago Lima, Sandra Trigo, Eduarda Silveira, Gabriela Jorge da Silva, Sara Domingues
…isease. First-line anti-TB drugs are considered safe during pregnancy and lactation. In contrast, second-line drugs have a less well-established safety profile during breastfeeding, and the available evidence regarding their excretion in breast milk remains limited; therefore, th…
Morton AJ, Roddy Mitchell A, Melville RE, Hui L, Tong SYC, et al.
Pregnancy may be associated with risk of developing tuberculosis (TB) in those infected with Mycobacterium tuberculosis (Mtb). The perinatal period could provide opportunities for targeted screening and treatment. This study aims to synthesise published literature on Mtb infectio…
Qi Nie, Yuan Liu, Fan Xiao, Yong Zhou, Tingting Fu, et al.
…extensively drug-resistant tuberculosis (pre-XDR-TB) during pregnancy poses a formidable clinical challenge, particularly when complicated by tuberculous meningoencephalomyelitis (TBMEM), While the WHO operational handbook provides a general framework for drug-resistant TB, robus…
Grace Montepiedra, Lisa Aaron, Gerhard Theron, Katie McCarthy, Sarah Bradford, et al.
…eeks of isoniazid preventive therapy (IPT) initiated during pregnancy (immediate IPT) versus deferring to week 12 postpartum (deferred IPT) in people with HIV on antiretroviral therapy, showed higher than expected hepatotoxicity. We investigated the potential roles of antiretrovi…