Showing 101–125 of 200 documents
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Vega Pangaribuan, Muhammad Arifin Parenrengi, Wihasto Suryaningtyas
…e literature on the clinical presentation and management of pediatric cervical spine tuberculosis (CST) and evaluate the outcomes of conservative or surgical treatment based on anatomical location (craniovertebral junction [CVJ], subaxial, and cervicothoracic junction). **METHOD…
Sharma S, Sarin R, Sahu G, Shukla G
Background Pediatric tuberculosis (TB) constitutes 8% of the total caseload of TB. Children are particularly vulnerable to dissemination of disease and mortality. Aim To determine mortality rate, elucidate type of TB, causes and predictors of mortality, if any, in admitted pediat…
Jakhar S, Bitzer AA, Stromberg LR, Mukundan H
…l ages. However, the disease presents a larger challenge in pediatric populations, partially owing to the lack of reliable diagnostic standards for the early identification of infection. Currently, there are no biomarkers that have been clinically validated for use in pediatric T…
Jayagandan S, Singh J, Mudliar SR, Shankar P, Maurya AK, et al.
…ective Microbiological confirmation of tuberculosis (TB) in pediatric cases is challenging due to its paucibacillary nature and difficulty in specimen collection. This study aimed to validate stool as an alternative sample for the diagnosis of pediatric pulmonary TB via Xpert MTB…
Koji Yokoyama, Mitsukazu Mamada
…ratory factors associated with indeterminate QFT results in pediatric patients, with a focus on KD. Methods We retrospectively analyzed 147 pediatric QFT tests performed at a tertiary medical center in Japan between September 2019 and May 2025. Clinical characteristics and labora…
Zhu Y, Gan M, Ge M, Dong X, Yan G, et al.
…sis of infectious diseases in adults, while its efficacy in pediatric infections remains uncertain. We performed a retrospective analysis of 1,493 mNGS samples from pediatric patients with blood, central nervous system, and lower respiratory tract infections. The positive percent…
Kumar NP, Hissar S, Thiruvengadam K, Banurekha VV, Suresh N, et al.
Pediatric TB poses challenge in diagnosis due to the paucibacillary nature of the disease. We conducted a prospective diagnostic study to identify immune biomarkers of pediatric TB and controls (discovery cohort) and obtained a separate "validation" cohort of confirmed cases of p…
Aole Li, Yuhang Wu, Xinxin Zeng, Xi Zhang, Jiong Li, et al.
**OBJECTIVE:** Pediatric tuberculosis (TB) remains an important part of the global TB burden; however progress in this population has been slower and less consistent than that in adults. The influence of recent epidemiological shifts, including those following the COVID-19 pandem…
Gebremichael B, Abebaw TA, Moges T, Abaerei AA, Worede N
…limited. Therefore this study aimed to assess predictors of pediatric Tuberculosis in Public Health Facilities. Methods Unmatched case control study among a total samples of 432 (144 cases and 288 controls) were done from August to December 2016 in Bale zone, South East Ethiopia.…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
DesJardin CP, Chirenda J, Ye W, Mujuru HA, Yang Z
Background Historical neglect of pediatric tuberculosis (TB), compounding the absence of a universally effective vaccine, highlights the importance of successful treatment in combating the global epidemic. Furthermore, compliance with international standards of pediatric TB treat…
Mejia- Mertel J, Rojas -Hernandez J
…nical manifestations in HTLV-1, still studies are needed in pediatric population to improve diagnosis and treatment of infected patients. Methods Descriptive, retrospective cohort study, conducted in our referral pediatric hospital in Cali, Colombia. Included pediatric patients (…
Harichander S, Wiafe E, Mensah KB, Bangalee V, Oosthuizen F
…te the incidence of TB and drug-resistant (DR) TB among the pediatric population. It also reviews the therapeutic options available to treat the condition. Methods A comprehensive search for all relevant evidence was conducted. The following databases were searched: MEDLINE, CINA…
Mina'a Shahid, Kiran Hilal, Memoona Khan, Zainab Haider Ejaz, Sadaf Altaf, et al.
Pediatric liver masses encompass a diverse spectrum of benign and malignant lesions, with distinct patterns based on patient age. Optimal imaging is critical for timely diagnosis, management, and prognosis. This pictorial minireview categorizes pediatric liver masses by age group…
Kamble B, Malhotra S
…a, all ages have assumed importance including the burden of pediatric TB. The current study was carried out to study the profile of pediatric TB patients and factors associated with treatment outcome of these patients registered in Faridabad district of Haryana, India. Methods Th…
Herdea A, Marie H, Negrila IA, Abdel Hamid Ahmed AD, Ulici A
Background Pediatric osteoarticular tuberculosis (TB) remains a significant global health challenge, particularly in resource-limited settings, where delayed diagnosis and treatment frequently lead to severe long-term complications. Despite advancements in TB control, skeletal TB…
Zhao A, Butala N, Luc CM, Feinn R, Murray TS
Pediatric patients with untreated tuberculosis infection (TBI), also called latent TBI, are at risk of progression to active TB disease. The primary aim of this study was to identify factors associated with higher rates of missed appointments and failure to complete therapy for p…
Piastra M, Picconi E, Morena TC, Valentini P, Buonsenso D, et al.
…TB) in the adult setting, and it is even less common in the pediatric population. The presence of comorbidities and the possibility of a delayed diagnosis may further impair the clinical prognosis of critically ill patients with disseminated TB and acute respiratory failure. In t…
Gupta N, Kashyap B, Dewan P, Hyanki P, Singh NP
Aim and objectives The paucibacillary nature of pediatric tuberculosis (TB) makes diagnosis difficult. The aim of the study was to correlate the clinical spectrum of pediatric TB with microbiological diagnosis. Materials and methods Specimens from clinically suspected pediatric T…
Malhotra S, Dasgupta-Tsinikas S, Yumul J, Kaneta K, Lenz A, et al.
…aluate implementation of rifamycin-based regimens (RBR) for pediatric tuberculosis infection (TBI) treatment among 3 provider settings in a high-incidence county. Study design A multicenter, retrospective observational study was performed across 3 sites in Los Angeles County: an …
Gao LW, Yin QQ, Tong YJ, Gui JG, Liu XY, et al.
…stigate the clinical and genetic features of CGD in Chinese pediatric patients. Methods Pediatric patients with CGD from Beijing Children's Hospital, Capital Medical University, China, were enrolled from January 2006 to December 2016. Results A total of 159 pediatric patients wit…
Chapagain RH, Adhikari S, Bista B, Bhattarai T, Thapa P
… scrub typhus among the children admitted in tertiary level pediatric hospital for febrile illness. Methods A case control study was conducted among hospitalized children with acute febrile illness in a government pediatric referral hospital of central Nepal for two years (2021 t…
Gao P, Liu L, Zhang Z, Xu L, Wu C, et al.
…nd Intussusception is a frequent abdominal emergency in the pediatric population when the proximal bowel invaginates into the distal bowel. However, catheter-induced intussusception has not previously been described in pediatric renal transplant recipients, and the risk factors n…
Drobish I, Ramchandar N, Raabe V, Pong A, Bradley J, et al.
…losis (MTB) complex infections in children and 1%-2% of all pediatric tuberculosis infections. Treatment regimens and durations typically mirror recommendations for other types of extrapulmonary MTB, but there are significant variations in practice, with some experts suggesting a…
Yang G, Wen Y, Chen T, Xu C, Yuan M, et al.
…parse. This study aimed to analyze the clinical features of pediatric TE receiving surgical intervention. Methods We performed a retrospective study of children with empyema secondary to community-acquired pneumonia who underwent surgery in our institution. The clinical character…