Showing 76–100 of 200 documents
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Meehan SA, Sloot R, Draper HR, Naidoo P, Burger R, et al.
Background Diagnosing HIV and/or TB is not sufficient; linkage to care and treatment is conditional to reduce the burden of disease. This study aimed to determine factors associated with linkage to HIV care and TB treatment at community-based services in Cape Town, South Africa. …
Marks SM, Katz DJ, Davidow AL, Pagaoa MA, Teeter LD, et al.
…ns (blacks) (12% of the US population) accounted for 41% of HIV diagnoses during 2008-2014. HIV infection significantly increases TB and TB-related mortality. TB rate ratios were 6 to 7 times as high in blacks versus US-born non-Hispanic whites (whites) during 2013-2016. We analy…
Umulkhairah Onyioiza Arama, Oluwatoyin Ayo-Farai, Mosunmade Oshingbesan, Bushra Murtaza, Sana Rasheed, et al.
Human immunodeficiency virus (HIV) and tuberculosis (TB) co-infection in Nigeria are medical conditions of public health importance because they double the country's and its citizens' burden. Several management measures, including artificial intelligence (AI), are crucial for pro…
Maemun S, Mariana N, Rusli A, Mahkota R, Purnama TB
Background The HIV epidemic remains a public health problem with rising tuberculosis (TB) numbers around the world. Antiretroviral (ARV) therapy (ART) is essential to increase the survival of patients with TB-HIV coinfection. The aim of this study is to investigate the effect of …
Goovaerts O, Massinga-Loembé M, Ondoa P, Ceulemans A, Worodria W, et al.
…atory syndrome (TB-IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral therapy (ART). The exact contribution of T cells, natural killer (NK) cells, and monocytes to TB-IRIS development remains unclear. Here, we studied the expression of e…
Tola A, Mishore KM, Ayele Y, Mekuria AN, Legese N
…mics of Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) causes major global health challenges in the twenty-first century. TB-HIV co-infected people are facing multifaceted problems like high lost to follow up rates, poor treatment adherence, high TB recurrence rate, and…
Negash M, Tsegaye A, Wassie L, Howe R
Background Previous studies reported HIV infection alters the distribution and function of γδ T cells and their subsets. γδ T phenotypes in healthy and diseased individuals has received little attention in Ethiopia. We conducted this study to analyze the distribution of γδ T cell…
Abrahamyan A, Hann K, Akopian K, Grigoryan R, Petrosyan O, et al.
Introduction Poor human immunodeficiency virus (HIV) testing practices and underreporting of HIV-related data in TB information systems remain barriers to effective care for TB-HIV co-infected patients. HIV testing and recording practices in national TB program have not been form…
Ye X, Liu F, Cheng Z, Xie F
…inetics (PK). These complexities are further exacerbated in HIV-TB co-infected patients, where nevirapine is often co-administered with rifampicin/isoniazid-based anti-tuberculosis (TB) therapies. Rifampicin, a strong CYP3A4 inducer and moderate CYP2B6 inducer, and isoniazid, a m…
Rewari BB, Kumar A, Mandal PP, Puri AK
Introduction : HIV and tuberculosis (TB) are two of the most challenging infections faced by humanity and place immense burden on health care systems worldwide. Both HIV and TB impact one another's progression. Areas covered : HIV is the most important risk factor for progression…
Ayele BA, Amogne W
…tion with high rates of morbidity and mortality. Underlying HIV infection often increases susceptibility for acquiring TB and also complicates TB treatment. The study objectives were to assess the burden of CNS TB and associated factors in treatment experienced HIV infected adult…
Yongkang Mao, Bennan Zhao, Lijuan Lan, Fengjiao Gao, Xiaoxia Ren, et al.
…abetes mellitus (T2D) and pulmonary cavitation in male with HIV-tuberculosis (TB) coinfection, as well as to quantify the relationships between glycemic indicators [HbA1c and fasting plasma glucose (FPG)] and cavity size. The robustness of these correlations was further validated…
Akanbi K, Ajayi I, Fayemiwo S, Gidado S, Oladimeji A, et al.
…use of death in patients with Human Immunodeficiency Virus (HIV) in developing countries. World Health Organization (WHO) recommends 85% treatment success rate for all TB cases as an indicator of TB control. The study aimed at determining TB treatment success rate among TB-HIV co…
Sinai I, Cleghorn F, Kinkel HF
…ly and is closely associated with the country's devastating HIV epidemic. The separation of HIV and TB services in primary healthcare services in South Africa hampers TB case finding in patients who are co-infected with HIV and TB. This operational proof of concept study assessed…
Herce ME, Morse J, Luhanga D, Harris J, Smith HJ, et al.
Background Patients with HIV-associated tuberculosis (TB) often have their TB and HIV managed in separate vertical programs that offer care for each disease with little coordination. Such "siloed" approaches are associated with diagnostic and treatment delays, which contribute to…
J E Akumu, C Sekaggya-Wiltshire, S Babirye, J Musaazi, P E Kukundakwe, et al.
**OBJECTIVE:** Antiretroviral therapy has extended HIV patient survival, increasing non-communicable disease prevalence like diabetes mellitus. Strong links exist between HIV, TB, and diabetes. This study examined diabetes prevalence among adults with TB and HIV, or co-infection …
Rau A, Wouters E, Engelbrecht M, Masquillier C, Uebel K, et al.
…utes a major health risk for healthcare workers (HCWs). The HIV epidemic equally affects the workforce because of the mutually reinforcing epidemiology of HIV and TB. Stigmas associated with HIV and TB have become so intricately entangled that they stop some HCWs from seeking car…
Owolabi RS
…TB is the commonest cause of death among people living with HIV (PLHIV) in Nigeria. It is difficult to diagnose TB among PLHIV and diagnosed patients often experience poor treatment outcome. Although, PLHIV are living longer because of increased access to antiretroviral therapy (…
Liu Q, Yu C, Cheng J, Jiang Y, Xu Y, et al.
…cells, but also highly expressed on the T cells membrane in HIV-1 negative patients with tuberculosis (TB). However, the study on membrane-bound IL-22+ cells of HIV-1 infected patients is rare. Therefore, we investigated antigen-specific membrane-bound IL-22+ T cell subsets in My…
Riti Sharan, Yi Zou, Bindu Singh, Vinay Shivanna, Edward J Dick, et al.
Most HIV-negative individuals exposed to Mycobacterium tuberculosis (Mtb) control infection as latent TB infection (LTBI), but HIV co-infection greatly increases progression to tuberculosis (TB), the leading cause of death in people living with HIV (PLHIV). Although combination a…
Enane LA, Eby J, Arscott-Mills T, Argabright S, Caiphus C, et al.
… (HCW) approaches, and supported interventions in TB and TB-HIV (human immunodeficiency virus) care for adolescents and young adults (AYA, aged 10-24 years). DESIGN: Semi-structured interviews with HCW in TB clinics, analyzed using thematic analysis. RESULTS: Sixteen HCWs were in…
Davy-Mendez T, Shiau R, Okada RC, Moss NJ, Huang S, et al.
…ounty has some of the highest human immunodeficiency virus (HIV) and tuberculosis (TB) case rates of California counties. We identified TB-HIV co-infected patients in 2002-2015 by matching county TB and HIV registries, and assessed trends in TB-HIV case rates and estimated preval…
Wouters E, van Rensburg AJ, Engelbrecht M, Buffel V, Campbell L, et al.
…hcare workers (HCWs) are additionally confronted daily with HIV and its associated stigma, causing a syndemic . Early TB diagnosis and treatment are vital, but the uptake of these services through occupational healthcare units (OHUs) is low. The current study hypothesises that (1…
Katende B, Bresser M, Kamele M, Chere L, Tlahali M, et al.
…ic challenged health services globally, and in Lesotho, the HIV and tuberculosis (TB) services were similarly affected. Integrated, multi-disease diagnostic services were proposed solutions to mitigate these disruptions. We describe and evaluate the effect of an integrated, hospi…
Ponticiello MN, Nanziri LM, Hennein R, Ochom E, Gupta AJ, et al.
…D Stigma is a barrier to care for people affected by TB and HIV in Uganda, where these conditions remain endemic. While scales have been adapted and validated to measure stigma among TB-affected households in Uganda, there is a need for scales that measure the experiences of pers…