Showing 76–100 of 170 documents
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Grasa Lozano CD, Baro-Fernández M, Rubio-San-Simón A, Blázquez-Gamero D, López-Roa P, et al.
Background There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected. Methods After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time …
Pop R, Kaelin MB, Kuster SP, Sax H, Rampini SK, et al.
…d exposure to sputum smear positive tuberculosis (TB). NICE guidelines give support regarding investigation and treatment intervention, but not for contact definitions. Data regarding the reliability of any interferon gamma release assay (IGRA) in infants as a screening test for …
Djalal A, Côté-Daigneault J
…ground Inflammatory bowel disease (IBD) patients undergoing treatment with biological therapy are at increased risk of developing opportunistic infections such as tuberculosis (TB). Screening for latent tuberculosis is mandatory before initiating biological therapy such as Anti-T…
Karat AS, Gregg M, Barton HE, Calderon M, Ellis J, et al.
…n to inform the 2019 update of global tuberculosis (TB) IPC guidelines, asked: do triage and/or isolation and/or effective treatment of TB disease reduce MTB transmission in healthcare settings? Of 25 included articles, 19 reported latent TB infection (LTBI) incidence in healthca…
…in the US is reactivation TB in non-US-born (nUSb) persons. Guidelines recommend screening persons born in high TB burden countries for latent TB infection (LTBI) and treating if positive. We evaluated the LTBI cascade in primary care among nUSb persons in a large academic medica…
Nunzi A, Della Valle L, Lindfors Rossi EL, Ranucci G, Mallegni F, et al.
Background Identification of latent tuberculosis infection (LTBI) is a critical step of tuberculosis surveillance, especially in low-incidence countries. However, it is limited to situations with a higher probability of developing active disease, e.g., patients with hematological…
Chiang CY, Chen CH, Feng JY, Chiang YJ, Huang WC, et al.
…l proportion of TB among solid organ transplant recipients. Treatment of TB among recipients is complicated by the drug-drug interactions between anti-TB drugs and immunosuppressants. TB is associated with an increased risk of graft rejection, graft failure and mortality. Detecti…
Jun YK, Chun J, Kang EA, Lee HJ, Im JP, et al.
… factor (anti-TNF) is an effective biological agent for the treatment of moderate-to-severe active ulcerative colitis (UC) refractory to conventional therapy. On the other hand, anti-TNF therapy is strongly associated with a potential risk of tuberculosis (TB). Active TB is a cri…
Kawatsu L, Kaneko N, Imahashi M, Kamada K, Uchimura K
…actor for progression to active TB disease for persons with latent TB infection (LTBI). Screening for active TB and LTBI, and TB preventive therapy (TPT) is recommended, however, clinical practices regarding LTBI screening for HIV positive population have not been uniform, result…
Black DA, McBrien SW, Gersh J, Ghassemieh B, Narita M, et al.
…on in the United States will require improved detection and treatment of latent TB infection among non-U.S.-born residents who remain at disproportionate risk of TB disease. To inform targeted testing efforts, we evaluated risk of TB disease among non-U.S.-born residents of Washi…
Kelly AM
…pared with waiting 21 days for culture results. The shorter treatment regimen for latent TB infection with weekly isoniazid and rifabutin for 12 weeks provides treatment as effective as the traditional daily isoniazid for 6 months, but with better adherence from patients.
Ghoshal AG, Halder A
…sed risk of tuberculosis (TB) reactivation in patients with latent tuberculosis infection (LTBI) has been recorded for anti-tumor necrosis factor (TNF) agents and, to a lesser extent, for the nonanti-TNFα targeted biologics. Use of both biologic agents and Janus kinase (JAK) inhi…
Teo AKJ, Rahevar K, Morishita F, Ang A, Yoshiyama T, et al.
…ecuring an early diagnosis, as well as adhering to their TB treatment. All countries emphasised the need for person-centred approaches that include the creative application of new technology and tailored incentive programs, as well as reconceptualisation of how we provide treatme…
Ridho A, Alfian SD, van Boven JFM, Levita J, Yalcin EA, et al.
…dherence to medication in tuberculosis (TB) hampers optimal treatment outcomes. Digital health technology (DHT) seems to be a promising approach to managing problems of nonadherence to medication and improving treatment outcomes. Objective This paper systematically reviews the ef…
Bonde Christiansen S, Ainsworth MA
Background Guidelines generally recommend a combination of immunological assays and chest X-ray imaging (CXR) when screening for latent tuberculosis infection (LTBI) prior to biologic treatment in inflammatory bowel disease (IBD). Objective To investigate whether CXR identify pat…
Alpaydın AÖ, Turunç TY, Avkan-Oğuz V, Öner-Eyüboğlu F, Tükenmez-Tigen E, et al.
Objective Latent tuberculosis infection (LTBI) screening is strongly recommended in the pre-transplant evaluation of solid organ transplant (SOT) recipients, although it remains inadequate in many transplant centers. We decided to investigate pre-transplant TB risk assessment, LT…
Hasan T, Au E, Chen S, Tong A, Wong G
…bjective Immunosuppressed individuals are at a high risk of latent tuberculosis infection (LTBI) and clinical practice guidelines for the screening and management of LTBI in at-risk patients have been developed. We assessed the scope, quality and consistency of clinical practice …
Zhang L, Zou X, Jiang N, Xie L, Liu J, et al.
… patients are at high risk for TB, but so far, there are no guidelines for TB prevention and management targeting this population in China. This study aims to investigate the incidence of active tuberculosis (ATB) and to explore the risk factors for developing ATB in SLE patients…
Diel R, Nienhaus A
…stant TB (MDR-/RR-TB). Methods Based on the current therapy guidelines of the German Central Committee against Tuberculosis and most recent renumeration data of the Statutory Health Insurances (SHI), this study estimates the mean in- and outpatient costs per adult infectious pulm…
Paton NI, Borand L, Benedicto J, Kyi MM, Mahmud AM, et al.
Asia has the highest burden of tuberculosis (TB) and latent TB infection (LTBI) in the world. Optimizing the diagnosis and treatment of LTBI is one of the key strategies for achieving the WHO 'End TB' targets. We report the discussions from the Asia Latent TubERculosis (ALTER) ex…
Park HY, Choi SH, Kim D, Hwang J, Kwon Y, et al.
…d with gastric cancer plus a cancer-free control group. The latent TB infection (LTBI) screening status, TB incidence, and potential confounders in each cohort were analyzed, and the risk of TB was analyzed using a Cox proportional hazard model. Results LTBI tests were performed …
Silveira MBV, Ferrarini MAG, Viana PO, Succi RC, Terreri MT, et al.
…a release assays (IGRAs) in paediatric TB are lacking, many guidelines do not recommend their use for TB diagnosis in this population in Brazil. Objective To evaluate the performance of an IGRA by investigating its concordance with the tuberculin skin test (TST) and the role of I…
Tal R, Lawal T, Granger E, Simoni M, Hui P, et al.
…ased in recent years after assisted reproductive technology treatments. Despite rising emigration rates to the United States, guidelines to identify those with latent tuberculosis or female genital tuberculosis in fertility centers do not exist. Objective This study aimed to char…
Oh CE, Menzies D
Diagnosing and treating latent tuberculosis infection (LTBI) is an important part of efforts to combat tuberculosis (TB). The Korean guidelines for TB published in 2020 recommend 2 LTBI regimens for children and adolescents: 9 months of daily isoniazid (9H) and 3 months of daily …
Christoph Zeyen, Ruben Heuer, Brit Haecker, Tom Schaberg, Alexander Nast
…re initiating MTX or IL-17/IL-23/IL-12/23p40 inhibitors for latent tuberculosis infection (LTBI) is supported by indirect evidence of TB reactivations with TNF inhibitors. However, direct evidence for MTX or IL-17/IL-23/IL-12/23p40 inhibitors is limited. To better evaluate the ri…