Showing 51–75 of 79 documents
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Declan I Emegano, Basil B Duwa, A G Usman, Hijaz Ahmad, Dilber Uzun Ozsahin, et al.
…eases the risk of active TB recurrence and prolongs medical treatment for tuberculosis (TB). The study focuses on using advanced machine learning (ML) techniques to predict TB incidence and HIV-TB co-infection using data from the 2023 World Health Organization (WHO) Global TB bur…
Stoica Călăraşu C, Popa Miulescu AM, Turcu AA, Nitu FM
…s (HIV) / tuberculosis (TB) raises important diagnostic and treatment problems as the lung is one of the target organs for HIV. Studies have shown that an HIV patient is 5-15 times more likely to switch from Koch's bacillus-infected status to active tuberculosis. Material and met…
Wondmagegn T, Damtie D, Genetu M, Biadgo B, Lemma M, et al.
… lymphocyte subpopulations before and after anti-tubercular treatment and the effect of intestinal parasites on the cell populations of tuberculosis patients before the initiation of anti TB treatment. Method A prospective cohort study was conducted in the outpatient TB Clinic, U…
Birhanu MY, Bekele GM, Jemberie SS
…both developing and developed countries has made diagnosis, treatment, and control of tuberculosis more difficult. The PCR assay, which is a fast and sensitive technique and an alternative method for detecting multidrug-resistant tuberculosis, is used to determine rifampicin (RIF…
Berra TZ, Gomes D, Ramos ACV, Alves YM, Bruce ATI, et al.
… of 0.69% per month in TB and human immunodeficiency virus (TB-HIV) co-infection, a fall of 0.01% per month in general and lung TB and a fall of 0.33% per month in extrapulmonary TB. With the breakpoint technique, general and pulmonary TB changed in structure in late 2007, and ex…
Marian Loveday, Jennifer Hughes, Nobuhle Mchunu, Nonhlanhla Yende-Zuma, Kerry Holloway, et al.
… in pregnant women. **METHODS:** Pregnant women initiating treatment for multidrug-resistant/rifampicin-resistant (MDR/RR) TB from 1 January 2018 to 31 March 2024 were included in this prospective, observational study. Maternal TB treatment and pregnancy outcomes were documented…
Gerades Dely Djoufack, Lem Edith Abongwa, Allan Olayemi Campbell, Julian Sydney Olufemi Campbell, Kabir Gorden, et al.
… higher risk of Mycobacterium tuberculosis (MTB) infection. TB-HIV coinfection complicates disease management due to drug interactions, overlapping toxicities, immune reconstitution inflammatory syndrome, and high treatment burdens, potentially driving drug resistance. The emerge…
Ohene SA, Fordah S, Dela Boni P
…. The study objective was to assess the characteristics and treatment outcomes of children with TB from multiple health facilities in Accra, Ghana. Methods A retrospective analyses was conducted using secondary data on children less than 15 years collected from 11 facilities duri…
Roen AO, Podlekareva D, Miller RF, Mocroft A, Panteleev A, et al.
…in 12 months. Use of rifamycin/isoniazid/pyrazinamide-based treatment (HR 0.67, 95% CI 0.50-0.89), TB drug susceptibility testing (DST) and number of active TB drugs (DST + . Lower HCI was associated with an increased probability of death; 30% (95% CI 26-35) vs. 9% (95% CI 6-13) …
Atwine D, Bonnet M, Taburet AM
…ugs in human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection treatment but with complex drug interactions, efficacy and safety challenges. We reviewed recent data on EFV and RH interaction in TB/HIV high-burden countries. Methods We conducted a systematic review of stu…
Gebremicael G, Gebreegziabxier A, Kassa D
…enes in the survived control was increased at the end of TB treatment from that at baseline, while decreased in the deceased group. The expression of PTPRCv1, CD3E, CCL5, and IL7R host genes in peripheral blood of patients with TB-HIV coinfected can potentially be used as a predi…
Ogbudebe CL, Adepoju V, Ekerete-Udofia C, Abu E, Egesemba G, et al.
… Understanding the factors that influence tuberculosis (TB) treatment outcomes in children is key to designing interventions to address them. This study aimed to determine the case category distribution of childhood TB in Nigeria and assess which clinical and demographic factors …
Rupani MP, Vyas S
…d a descriptive cross-sectional study among 234 co-infected TB-HIV patients notified in the Bhavnagar region of western India from 2017 to 2020 to estimate the costs incurred, followed by in-depth interviews among program functionaries and patients to explore the solutions for re…
Ayele TK, Doungmo Goufo EF, Mugisha S
… both HIV and TB diseases, case finding for TB and HIV/AIDS treatment. This study aimed to develop optimal HIV/AIDS-TB co-infection mathematical model to explore the best cost-effective measure to mitigate the disease burden. The model is analysed analytically by firstly segregat…
Weldegebreal F, Mitiku H, Teklemariam Z
…ctions are endemic. The aim of this study was to assess the treatment outcome of tuberculosis among Human Immunodeficiency Virus positive patients attending in three hospitals of Eastern Ethiopia. Methods A retrospective clinical record review was conducted for 627 Tuberculosis a…
Ngouanom Kuate MP, Bongomin F, Ndip RN
…cribe the first case of a patient surviving from SARS-CoV-2-TB-HIV triple co-infection in Cameroon. A 36-year-old Cameroonian woman presented at the emergency unit of the Jamot Hospital, Yaoundé with symptoms of anorexia, productive cough, weight loss, and fever. The SARS-CoV-2 r…
Hosseinian K, Gerami A, Bral M, Venketaraman V
…he emphasis is on the changes that occur as a result of HIV coinfection. With the progression of HIV infection, the primary source of IFN-γ changes from CD4+ to CD8+ T cells, especially when latent TB advances to an active state. This study sheds light on the necessity of develop…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
…urvival. Therefore, this study aimed to assess Tuberculosis treatment outcomes and associated factors in South Gondar Administrative Zone Governmental Hospitals, Northwest Ethiopia, 2023. Method and Materials A hospital-based retrospective study was conducted from July 1 to Augus…
Berhan A, Almaw A, Solomon Y, Legese B, Damtie S, et al.
…urvival. Therefore, this study aimed to assess Tuberculosis treatment outcomes and associated factors in South Gondar Administrative Zone Governmental Hospitals, Northwest Ethiopia, 2023. Method and materials A hospital-based retrospective study was conducted from July 1 to Augus…
Eliza Miranda Ramos, Carolina Braga Sisti, Sérgio Beltrão de Andrade Lima, Emerson Luiz Lima Araújo, Lúcia Dias da Silva Guerra, et al.
…e HP in South America, highlighting factors associated with treatment abandonment and mortality. **METHODS:** Scientific articles were searched in PubMed, EMBASE, LILACS, SciELO, Web of Science, and Cochrane databases, published in Portuguese, English, or Spanish between 2013 an…
Kshitij Agarwal, Adam T Gray, Tudor P Toma, Valentina Luzzi, Lorenzo Corbetta
…larly in the context of multidrug-resistant TB (MDR-TB) and TB-HIV co-infection. Traditional surgical interventions, such as lung resection and pneumothorax induction, have largely been phased out with the advent of modern antibiotic regimens. However, emerging evidence suggests …
Gabriela Pizarro Ossa Ferro Henriques, Guilherme Barbosa Pinto, Erika Yukie Ishigaki, Nicoly Caroline de Andrade Delmondes, Daniel Ayabe Ninomiya, et al.
… health concern globally and in Brazil. Although ambulatory treatment is recommended for most patients, hospitalizations still occur due to severe clinical presentations, social vulnerability, or treatment complications. **METHODS:** We conducted a retrospective, observational s…
de Oliveira MCB, Sant'Anna CC, Raggio Luiz R, Kritski AL
…em. We aimed to analyze the risk factors for unfavorable TB treatment outcomes among adolescents in Rio de Janeiro, a Brazilian city with a high burden of TB. This is a retrospective study of adolescents (10-18 years) with TB notified in Rio de Janeiro, from four national databas…
Sebastião CS, Samulengo J, Sacomboio E, Francisco NM, Teixeira C, et al.
…oreover, we examined the evidence-based indications for the treatment of active TB in Angola. This study evaluated the medical records of 176 patients screened for TB from January to September 2016 in Luanda, the capital city of Angola. Approximately 66.5% of the patients were ne…
Belew H, Wubie M, Tizazu G, Bitew A, Birlew T
…uberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam, northwest, Ethiopia. Methods Institution based unmatched case-control study was employed to determine the predictors of tuberculosis infection among adults visiting anti-retrovir…