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Per Bjorkman, M.D., Ph.D.
Background: Tuberculosis (TB) and HIV are leading causes of disease and death in Subsaharan Africa. Antiretroviral therapy (ART) dramatically improves prognosis in HIV infection, but TB is still a common complication in HIV-infected subjects. Management of TB-HIV co-infection is …
Taya Rizki Arini Harahap, Tambar Kembaren, Endang Sembiring
…ulmonary TB. Aim: To assess difference in survival rates of HIV patients with pulmonary TB and extra pulmonary TB. Results: Based on Fisher's Exact test, it was found that there was no statistical difference survival rates of HIV patients with pulmonary TB and extra-pulmonary TB …
Harmeet Pal Singh Dhooria, Anna Gupta, Gurdeep Singh Dhooria, Deepinder Chhina, Akashdeep Singh
Tuberculosis and HIV together have been referred to as the "cursed duet" and HIV has been found to reduce the effectiveness of treatment of TB. The aim of the study was to determine the status of HIV infection in patients of Tuberculosis and compare with patients of TB infection …
Subencha Pinsai
Abstract Background Tuberculosis (TB) and HIV are one of the significant public health problems in Thailand, and an estimated 15,000 individuals have a dual infection. Both HIV and TB each disease speeds up the progression of each other. TB is the leading cause of death in HIV-in…
Vasanti C. Visawale, Shilpa Patil, Ameeta Joshi
Background: Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) constitute a major burden of infectious diseases in India. TB is the most common opportunistic infection and a leading cause of death among HIV positive patients. This study was conducted to assess the HIV–TB co…
Claudia L. Do Vale, Saraladevi Naicker, Christopher K. Lippincott
…achiat A.I. Musenge E. Wadee S. Naicker S. Renal failure in HIV-positive patients—a South African experience.Clin Kidney J. 2013; 6: 584-594https://doi.org/10.1093/ckj/sft128Crossref PubMed Scopus (19) Google Scholar,2Izzedine H. Baumelou A. Deray G. Acute renal failure in HIV pa…
Sanskar Virmani, Kamila Ubbiniyazova
…lity among people living with Human Immunodeficiency Virus (HIV) globally, accounting for approximately 167 000 deaths annually despite expanded antiretroviral therapy coverage. The World Health Organization Global Tuberculosis Report 2025 estimates 10.8 million incident TB cases…
Sanskar Virmani, Kamila Ubbiniyazova
…lity among people living with Human Immunodeficiency Virus (HIV) globally, accounting for approximately 167 000 deaths annually despite expanded antiretroviral therapy coverage. The World Health Organization Global Tuberculosis Report 2025 estimates 10.8 million incident TB cases…
Hina Sadiq, Nasim Akhtar, Sana Tahir Virk, Kazim Abbas Virk, Muhammad Arslan Tariq, et al.
Background: Co-infection of HIV and TB is a significant public health concern, as these two diseases can interact and worsen each other's effects, leading to more severe health outcomes. The objective of this study was to stratify CD4 count according to different presentations of…
Nicola Wearne, Valérie A. Luyckx
…rvival. TB was diagnosed at an earlier stage in people with HIV (PWH) compared with those without (21 versus 60 days from symptom onset). Earlier diagnosis is likely due to highly structured HIV care in Uganda, which includes routine monitoring and early TB screening. AKI was dia…
Human Sciences Research Council
…ive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in …
E. I. Veselova, Anna Panova, Grigory Kaminskiy, Vadim Testov, Anastasia Samoilova, et al.
…osis (MTB) DNA and DST. It is critical important for TB and HIV co-infected patients due to acute and severe TB manifestation. <b>Aims:</b> To study efficiency of MTB DNA detection (MTBD) by MGM among new TB cases with HIV positive (HIV+) and HIV negative (HIV-) status. <b>Method…
Vanisree Ramanathan, Mayur Giri, Ram Gudgila, Sharayu Mhamane, V S Yadav, et al.
Background: HIV TB is a rising challenge in India which a few studies have explored this association in Indian population. Recent studies are missing to help form policies and understand socio demographical factors which affect the prevalence and influence the treatment outcome. …
Ethel M Weld, MD
…), among antiretroviral therapy (ART)-nave individuals with HIV-1 receiving rifampin-based TB therapy Tuberculosis (TB) is the most common cause of death in people with HIV worldwide. Among patients with HIV, the incidence of TB per year is about 5-10%. The two diseases are now …
Centre Hospitalier Universitaire Saint Pierre
…onary TB after two months and at the end of TB treatment in HIV patients. Evaluate 18F-FDG-PET/CT as a TB treatment response monitoring tool. Design The investigators performed baseline FDG-PET/CT, another FDG-PET/CT after 2 months of TB treatment and a PET/CT at the end of trea…
Gonzalo Alvarez, MD
… (TB) is the leading cause of death in people infected with HIV worldwide. South Africa has one of the highest rates of tuberculosis and HIV in sub Saharan Africa and the world. Infection with HIV can result in activation of the latent form of TB to its active form. In places lik…
Lara Esteves Coelho, C. Chazallon, D. Laureillard, Rodrigo Escada, J. B. Ntakpe, et al.
…tiretroviral therapy (ART) initiation in people living with HIV (PWHIV) treated for tuberculosis (TB) may be complicated due to the occurrence of tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS). Integrase inhibitors (INSTIs), by providing a faster HI…
Л. В. Пузырева, А. В. Мордык, S. A. Rudenko
…ot lost its significance due to the overlapping epidemic of HIV infection and the addition of specific lesions at its late stages. It is due to the lack of adherence to antiretroviral therapy in a large number of patients. The high mortality rate in HIV-associated TB requires an …
Graeme Meintjes, MD MPH PhD
…sis (TB) is the most common opportunistic infection amongst HIV-infected patients starting antiretroviral therapy (ART) in developing countries and thus the most frequent form of immune reconstitution inflammatory syndrome (IRIS). Paradoxical TB-IRIS occurs in 8- 43% of patients …
Mariana Fontes Gonzaga, Vanessa Alves Nascimento, Luciano Araújo de Souza Filho, Matheus Freitas Santos, Marco Aurélio de Oliveira Góes
Tuberculosis-HIV coinfection represents one of the main causes of morbidity and mortality among people living with HIV (PLHIV), especially in high-burden countries such as Brazil. HIV compromises immunity, favoring tuberculosis reactivation and more severe clinical forms. This st…
Alvina Widhani, Teguh Harjono Karjadi, Evy Yunihastuti, Desi Salwani, Angga Pramudita, et al.
Introduction. Treatment of tuberculosis (TB) in HIV patients is complicated due to numerous comorbidities and possible adverse effects. One of which is cutaneous adverse drug reaction (CADR). This adverse event is often difficult to manage because of multiple medications the pati…
Sergey Skornyakov, Elena Burylova, Е. В. Сабадаш, Igor Medvinskiy, Alexey Demin, et al.
<b>Background:</b> Tuberculosis (TB) and HIV, especially in the later stages, can be accompanied by changes in microvessels. <b>Aims and objectives:</b> To study the state of retinal microvessels in patients with TB and HIV/TB using optical coherence tomography (OCT). <b>Methods:…
Hina Sadiq, Nasim Akhtar, Sana Tahir Virk, Kazim Abbas Virk, Abeer Zafar, et al.
Background: Co-infection of HIV and TB is a significant public health concern. The relationship between increased HIV replication and low CD4+-TLC in HIV-positive patients with treatment interruptions is well documented. Moreover, TB preventive therapy is highly effective in redu…
Ekaterina Kulchavenya
…uction:</b> Co-infection with human immunodeficiency virus (HIV) has changed both the clinical presentation and the outcome of tuberculosis (TB) dramatically in the last few decades. <b>Material and Methods:</b> We have analyzed a cohort of 190 patients with isolated forms of ext…
Amartya Chakraborti, SushilKumar Munjal, Vijender Mudavath, Puneet Arora, Manpreet Bhall
…ine screening of presumptive tuberculosis (TB) patients for HIV was advised by the Treatment and Operational Guidelines of TB in India in 2016. This was in contrast to the earlier policy in which only diagnosed TB cases underwent HIV screening. Keeping this in mind, our study was…