Showing 1–25 of 200 documents
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Tulane University
Pediatric tuberculosis (TB) continues to pose diagnostic challenges in low- and middle-income countries with high rates of TB disease, due to the well-described impact of paucibacillary disease in children, and current TB culture and polymerase-chain reaction tests are of limited…
Kapil Saharia
Background: The incidence of pediatric tuberculosis (TB) in North Carolina decreased from the mid 1990s to 200l. In 2002, the number of pediatric TB cases increased from 9 in 2001 to 32 in 2002, representing more than a 250% increase. Objective: To describe the epidemiology and c…
Meyer Children's Hospital IRCCS
…s were reported in 2020, of which 1 million occurred in the pediatric population. However, epidemiological data available on tuberculosis (TB) in pediatric age are extremely limited due to diagnostic challenges in this patient category. Furthermore, children are almost never incl…
Yoonsun Yoon, Joon‐sik Choi, Hanpum Yoon, Sun Young Cho, Yae‐Jean Kim
…reported. There have been few reports of TB exposure in the pediatric hematology-oncology ward. Methods A mother of a pediatric cancer patient was diagnosed with active TB with a cavity. Contact investigation was performed on patients, their parents, and healthcare workers who we…
Daniela Russo
…rculosis (TB) remains a major public health problem. In the pediatric population, the prevention and diagnosis of TB is considered a major challenge. For this reason, this scoping review will be conducted in order to systematically map the research carried out in this area and id…
Jeffrey I. Campbell, Thomas J. Sandora, Jessica E. Haberer
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Ananya S Willsraj, Suba Joice, Y Dishan, Blessed Singh, Ajin Chandran
…ials and methods: A cross-sectional study was done among 90 pediatric HHC (5–15 years) of 48 microbiologically confirmed pulmonary TB patients notified in Neyyattinkara TB unit from March 2021 to July 2022. Data were entered and analyzed using SPSS trial version 26. All qualitati…
Patricia Comella-del-Barrio, José Luis Izquierdo-García, Ramón Campos‐Olivas, Clara M. Santiveri, Jesús Ruı́z-Cabello, et al.
…al scoring systems limited by the TB clinical presentation. Pediatric TB diagnosis research should be focused on new biomarkers from non-invasive and non-sputum-based samples. By metabolomics we can obtain a “fingerprint<i>”</i> of the metabolites presents in a biological sample,…
Anita Uka, Frédéric Méchaï, Daniela Maria Cirillo, Lorenzo Guglielmetti, Yousra Kherabi, et al.
Introduction Tuberculosis (TB) remains a leading cause of pediatric morbidity and mortality worldwide, with diagnostic and therapeutic challenges continuing to affect outcomes, including in high-income settings. The TBSure study investigated current practices in pediatric TB diag…
Özlem Tezol
Objectives: Pediatric tuberculosis is a major public health problem. Malnutrition characterized with wasting is prevalent among pediatric tuberculosis patients. We aimed to review pediatric tuberculosis cases by considering their nutrition manifestations. Materials and Methods: T…
Nadia E Hoekstra, Mark E. Anderson, James Gaensbauer
…logy and risk factors informing current American Academy of Pediatrics (AAP) guidelines on screening for pediatric latent tuberculosis infection (LTBI) have evolved over the past decade. To improve pediatric LTBI screening efficiency, we sought to reevaluate characteristics assoc…
Rafaela Baroni Aurílio, Adriana Rodrigues Fonseca, Ana Alice Amaral Ibiapina Parente, Maria de Fátima B. Pombo March, Marta Cristine Félix Rodrigues, et al.
…an be performed. This study aims to report a case series of pediatric patients with autoimmune rheumatic diseases, diagnosed with active TB in 2019, in a tertiary referral center in Pediatric Rheumatology and Pulmonology.
L. Perini, Aroldo Carvalho, Marcos Guchert, Rodrigo Marzola, Sónia Faria, et al.
Objective: Clinical and epidemiological analysis of pediatric patients with LTBI (latent tuberculosis infection). Method: Observational, descriptive, analytical and retrospective research, with data collection from medical records of patients suspected of having LTBI treated at a…
James P. Stevens, Cortney R. Ballengee, Raguraj Chandradevan, Amelia B. Thompson, Bess T. Schoen, et al.
…ts negative predictive value, moreover, was 99.9%. Multiple pediatric studies with a larger number of patients positive for tuberculosis have demonstrated IGRAs to have a higher sensitivity than TST (1,2). TSTs suffer from the subjectivity of the individual interpreting the skin …
Krunal Patel, Kinjal Patel, Pooja Gandhi, Bhavini Rathwa, Dipak M. Nakum
…ase caused by predominantly Mycobacterium tubercle bacilli. Pediatric tuberculosis is among the top 10 causes of death in children. India accounts for one fourth of the global tuberculosis burden, standing one among the thirty high TB burden countries. Hence, children in India ar…
L. Perini, Aroldo Carvalho, Marcos Guchert, Rodrigo Marzola, Sónia Faria, et al.
OBJECTIVE: Clinical and epidemiological analysis of pediatric patients with LTBI (latent tuberculosis infection). METHOD: Observational, descriptive, analytical and retrospective research, with data collection from medical records of patients suspected of having LTBI treated at a…
Manresana de Micobacteriologia, SL
…oble-blind, masked, compared with placebo clinical trial in pediatric population in contact with tuberculosis with or without tuberculosis infection. This trial aims to study the effect of the probiotic Nyaditum resae® at the level of specific Treg memory cells eight weeks after …
Amir Balakhmet
…lated deaths globally, especially in low-resource settings. Pediatric immune responses to Mtb infection have been understudied, owing in large part due to diagnostic challenges in children. We examined T cell responses in a pediatric cohort of Ugandan Mtb-infected children treate…
Wiwiek Setiowulan, redi rulandani, Helmy Rachman
Pediatric drug reaction with eosinophilia and systemic symptoms (DRESS) is a life-threatening uncommon disease that can be difficult to diagnose. We present a case of a 10-year old girl with ten days of high fever during her fifth week of ATT (consisting of isoniazid, rifampicin,…
Adrienne Katrin M. Guiang-Valerio
PV293 / #569 Case Report Poster Topic: AS18 - Pediatric SLE Introduction Systemic lupus erythematosus (SLE) is a systemic disease, which can affect multiple organ systems. Gastrointestinal (GI) involvement is rare in pediatric SLE and is under-recognized. On the other hand, gastr…
Naglaa Ibrahim, Saad Mansour, Ehab Abd El-Hamid Abd El-Salam, Rehab Ahmed Rabie
…ntrol group. This study was conducted at Zagazig University Pediatric Hospital. All patients were subjected to the following: Full history taking, full general examination, and investigation (Tuberculin test and chest X ray). Results: In the current study, 42% were male and (58%)…
Sumaiya Islam, Dona A. Kiriella, Olutobi Oridota, Avika Dixit
…th the most recent WHO guidelines on LTBI management in the pediatric population. Results We identified four subsections of the WHO guidelines: at-risk groups for LTBI testing, algorithms to rule out active TB disease, testing for LTBI, and TB preventive treatment options. Guidel…
Beuy Joob, Viroj Wiwanitkit
…n-Gamma Release Assay (IGRA)s for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease” with great interest (1). Stevens et al noted that “IGRA's are a useful tool to screen for LTBI, both prior to anti-TNF therapy and during treatment (1).” The important consideration …
Roxana Mansour Ghanaie, Abdollah Karimi, Leila Azimi, Seddon James, Mahshid Nasehi, et al.
…itations. We aimed to evaluate the prevalence of LTBI among pediatric household contacts of TB cases in two high-burden provinces in Iran. Methods: We conducted a cohort study in children who had been in household contact with a TB index. All subjects were assessed for active dis…
Hongmei Chen, Changxing Shen, Dan Li
…s, as a new generation ELISA-based method, shows promise in pediatric TB auxiliary diagnosis and LTBI discovery. The study underscores the importance of specialized TB judgment in achieving accurate diagnoses and suggests that the use of lymphocyte culture medium in place of plas…