Showing 176–196 of 196 documents
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Janmejaya Samal, Arnab Mondal
… the burden of TBI and management of TBI with TB preventive treatment (TPT) is of utmost importance in achieving the same. States in India adopt different models of implementation of testing and treating the TBI. Some of the states select subcontracting agencies to provide end-to…
Róisín Rynne, Sinead Collins, Róisín Hambly
…FERON/interferon-gamma-releasing assay (IGRA) for detecting latent tuberculosis infection (LTBI). The majority (97.5%) had negative IGRA results, with only two showing TB-like findings on CXR. No patients with positive IGRA had CXR signs of TB, and none began LTBI treatment based…
Daniela Russo
…ct with adults with TB and failure in LTBI investigation or treatment and context (C) is defined as diagnosis of TB disease. We will carry out a systematic search in the databases; VHL, Medline via PubMed, Cochrane, Scopus and Web of Science. The following descriptors will be use…
Jason R Andrews, MD
This trial is designed to determine whether modifying the dose of isoniazid for individuals according to their n-acetyltransferase 2 (NAT2) genotype could increase the probability of achieving equivalence of area-under-the-curve.
Candace M. Wilson, Philip Mitchelmore, Henry S. Dunning, TG Burden
<h3>Background</h3> The risk of latent <i>Mycobacterium tuberculosis</i> (LTBI) is higher among health care workers (HCW) than the general population. There is a lack of evidence about LTBI in HCW and only one study from Australia was found to examine HCW’s attitudes towards taki…
S Banzola, G. Clemente, Paolo Frignani, G Bisceglia, R Ferrara, et al.
…n Parma, showed poor adherence and lower completion rate of Latent Tuberculosis Infection (LTBI) treatment among 2701 refugees and asylum seekers, registered from 2013 to 2018. Soon afterwards, qualitative data analysis revealed that health operators, intercultural mediators and …
J Saxena, A Saraf, D Vaithiswaran, A Saleh
…(diagnosed at age 15; last flare at age 46) and treated for latent tuberculosis who presented to the emergency department (ED) with hemoptysis. Over the last six months, she had three ED visits for productive cough and intermittent hemoptysis. She was diagnosed with an upper resp…
Marina Pinheiro, Diana Moreira, Carla Valente, Maria do Carmo Meirelles Toledo Cruz, Ana Aguiar, et al.
… high, coverage varied, and completion rates for preventive treatments were low. Economic analyses supported the high cost-effectiveness of the screening programs, particularly when integrating both active TB and LTBI screening strategies. Conclusions The implementation of unifor…
Amirtha Gopalan, Meghna Gavali, Keerthivardhan Yerram
…pA). 2 We acknowledge the concern regarding the duration of latent tuberculosis infection (LTBI) prophylaxis.The three-month daily isoniazid plus rifampicin (3HR) regimen used in our cohort is a WHO-recommended LTBI treatment and is endorsed by the Indian National TB Elimination …
Jedsada Panthong
… in the hospital setting was instituted which followed the “Guidelines for the Investigation of Contacts of Persons with Infectious Tuberculosis: Recommendations from the National Tuberculosis Controllers Association and CDC” using the QuantiFERON®-TB Gold In-Tube assay (QFT-GIT)…
Mark Hatherill
…hat MTBVAC will provide improved protection, as individuals latently infected with live M.tuberculosis have an 80% lower chance of developing TB, and as MTBVAC contains most of the genes deleted from BCG and presents a wider collection of antigens to the host immune system. Precl…
Le Thi Luan, Cécile Charlois, Hugues Leroy, H. Cordel, Julie Figoni, et al.
Abstract Background Screening of active and latent tuberculosis among migrants is a public health concern but physicians’ practices are poorly known. The study aimed to evaluate physicians’ practices in France. Methods A national survey of physicians’ practices about infectious d…
Galymzhan Togizbayev, Aigul Turtayeva, Gulzhan Gabdullina, Zharkynay Akhmetova, Bibikhan Eraliyeva
…ive national clinical recommendations for the diagnosis and treatment of RA under the leadership of the Qazaq College of Rheumatology (QCR) in 2025. The QCR 2025 recommendations were developed by a national expert panel integrating international evidence with local epidemiologica…
Rina La Distia Nora, MD, PhD
…until now corticosteroids and cycloplegics are the mainstay treatment for uveitis. However, appropriate administration of anti-infective drugs is necessary in cases of infection. Inflammation in TB-associated uveitis is thought to be the result of the immune response that occurs …
West China Hospital
…ll a lack of accurate and effective means for screening for latent tuberculosis infection. The tuberculosis interferon-γ release test has recently received more and more attention as a means of screening for potential tuberculosis infection. However, how to apply tuberculosis int…
Ferhat Demir, Mukaddes Kalyoncu
Aim: We aimed to investigate the incidence of latent tuberculosis infection (LTBI) and seroconversion rate of LTBI screening tests under anti-TNF-α treatment, in our pediatric patients with chronic rheumatic diseases.Material and Methods: The data of 47 patients received anti-TNF…
Sara Matos, Ana Paula Duarte, Maria Almeida, Inês Correia Gonçalves, Mário Miranda, et al.
…caused by Mycobacterium tuberculosis. Despite the available treatment, it’s an important driver of global morbidity and mortality. It reaches mainly the lungs but can reach any organ. The main route of infection is inhalation of aerosolized particles or contaminated micro-droplet…
Yalçın Kara, Mahmut Can Kızıl, Merve İşeri Nepesov, Aslı Kavaz Tufan, Nuran Çetin, et al.
Abstract Introduction: Treatment with biological agents, which are classified as monoclonal antibodies, cytokines and fusion proteins, increases patient risk for developing tuberculosis (TB) and non-tuberculous mycobacterial infections. In this study, we aimed to investigate the …
Sashwanthi Mohan, Vidya Dharani, Parthopratim Dutta Majumder
…ous disease specialist advised against the need for ATT for latent tuberculosis. Despite the ophthalmologist’s recommendation, the patient refused to take ATT. At one and three-month follow-ups with corticosteroid treatment alone, the patient’s LE BCVA improved to 6/7.5, but ther…
Anusha Gopinathan, Shweta Sagar Naik, K.V. Leela, Sujith Ravi
…ffairs in our country, despite there being well-established treatment regimens for tuberculosis over the last 50 years. The pitfalls of the drug regimens existent in India are the rigid and prolonged drug schedules with its frequent dosing, side effects, and poor patient complian…
Jeffrey I. Campbell, Yamini Adusumelli, Mary Tabatneck, Susan N. Sherman, Gabriella S Lamb, et al.
…tract Background Understanding barriers and facilitators to latent tuberculosis infection (LTBI) diagnosis and care is needed to successfully treat children/adolescents with LTBI in the US. We explored physicians’ perspectives on pediatric LTBI diagnosis and care, and strategies …