Showing 151–175 of 200 documents
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Arash Zia Sheybani, Shaghayegh Hoseinzadeh, Shadi Habibnia
Background and Aim: Mycobacterium tuberculosis (M.tuberculosis) is one of the most dangerous infectious diseases all over the world.Diagnosis of M. tuberculosis based on the culture and phenotypic tests takes weeks that make them inappropriate methods to evaluate a definitive dia…
Tram Bich Nguyen, Élisabeth Mercier, Chandler H. Wong, Nada Hegazy, Md Pervez Kabir, et al.
…2012), and Sales et al . (2012) to quantitate Mycobacterium tuberculosis complex (MTBC) species, M. tuberculosis (MTB), and M. bovis (MB) in wastewater targeting genomic regions rv0577, RD9, and the deletion of RD4, respectively. The assays were validated for specificity using fo…
S. Sh. Sadikhodzhaev, R. A. Khakimova, Nematjon S. Mamasoliev, U. T. Sadikov
…c and behavioral risk factors associated with occurrence of tuberculosis relapse among tuberculosis patients during the COVID-19 pandemic in Fergana Region, Uzbekistan. Subjects and Methods. The article describes a cross-sectional study among tuberculosis patients admitted to hos…
T. Yu. Sаlinа, Т. И. Морозова
… katG, inhA, ahpC, rpoB genes associated with Mycobacterium tuberculosis (MTB) resistance to isoniazid (H) and rifampicin (R) in patients with various clinical manifestations of pulmonary tuberculosis (TB). Subjects and Methods . 441 sputum samples collected in tuberculosis patie…
Gudisa Bereda
Tuberculosis is a widespread, infectious disease caused by various strains of mycobacteria, commonly Mycobacterium tuberculosis. Tuberculosis not only responsible for an important proportion of the global burden of disease, but it is also an important contributor to maternal mort…
А. В. Мордык, Д. Г. Новиков, A. N. Zolotov, M. A. Romanova, N. A. Kirichenko, et al.
…be a potentially useful marker to assess innate immunity in tuberculosis patients. Patients and methods. The study included 28 children aged 4 to 14 years who contracted tuberculosis in the Omsk and Omsk regions between 2023 and 2024. Comparative analysis was conducted between ch…
Isabel Caballos, Andy Hernández-Montoto, Estela Climent, Ana Gil-Brusola, Ramón Martínez-Máñez, et al.
Tuberculosis (TB) is a chronic condition caused by Mycobacterium tuberculosis . According to WHO’s Global Tuberculosis Report 2024, TB has again become the leading cause of death from a single infectious agent, surpassing COVID-19 in 2023 and 2024 in terms of infectious disease d…
Lihui Guo, Bente Hollestelle, Samantha A. M. Tromp, Annemiek Dijkhuis, René Lutter
<b>Introduction:</b> M. tuberculosis is phagocytosed and can persist and survive inside macrophages. It is not clear why these infected macrophages do not become apoptotic. IDO1 is expressed abundantly in tuberculoid granuloma and catabolizes tryptophan, which impairs growth of i…
Yati Sri Hayati, Venty Aprilia Putri, Mifetika Lukitasari
Lung tuberculosis is still a government concern as an infectious disease that causesdeath. The prevalence of lung tuberculosis is still increasing, one of the causes is the highrate of transmission. Families caring for lung tuberculosis patients have a higher risk oftransmitted b…
Kiswendsida Yanogo Pauline, Schmit Jean-Luc, Sophie Fresse Anne, Meda Nicolas, Ganry Olivier
In order to assess the measures involved in the control of tuberculosis in the Somme Department, France, five years after the implementation of the French National Tuberculosis Program, we found it essential to describe the precise epidemiology on this disease. All reported cases…
Audu Onyemocho, Hassan Abiodun, Queen Chidinma Ogbuji, A. Osho, Shember-Agela Igbabul, et al.
Background: Nigeria, one of the high burden Tuberculosis countries, has developed various intervention strategies to ensuring universal access to quality-assured tuberculosis diagnosis and treatment. However, low case detection and unsuccessful treatment outcome still remains a s…
Richmond Ronald Gomes
Tuberculosis (TB) is prevalent in underdeveloped and developing countries, mainly in rural areas, with indistinct clinical manifestations. Lungs are the most affected organs; however, tuberculosis may invade almost all human body systems, including the liver. Isolated liver tuber…
N. Thamilpavai, K. Prabha, Ganesan Sreeprakash
Introduction: Tuberculosis is a disease that affects mostly young individuals in their productive formative years. The risk is 20–37 times greater in HIV co- infected individuals than among those without HIV. Spinal tuberculosis is uncommon in the western world as compared to Asi…
Yu.N. Khomyakov, Darya D. Zvyagintseva, T.I. Khomyakova
According to the World Health Organization Global Tuberculosis Report, published in 2022, tuberculosis and its drug-resistant forms are on the rise for the first time in recent years. The ability to become immune to anti-tuberculosis drugs is a fundamental feature of the tubercul…
Zeqing Bao, Yingyi Bao, Xiaocui Qin, Weibin Wu, Xia Zhang
…he molecular mechanisms of drug resistance of Mycobacterium tuberculosis in patients with pulmonary tuberculosis and its pharmacoeconomics. 
 Methods: Data pertaining to patients with primary tuberculosis treated in the First Affiliated Hospital of Zhaoqing Medical College, …
AR Ojewuyi, AO Odeyemi, AO Odeyemi
ABSTRACT Tuberculosis (TB) is one of the infectious diseases responsible for high morbidity and mortality across the world and more so in developing countries. According to WHO, one-third of the world's population is infected with the tubercle bacillus. A large proportion of pati…
Sukanya Sahu, Sandeep Rai Kaushik, Shweta Chaudhary, Amit kumar Mahapatra, Rukuwe Kappa, et al.
ABSTRACT Objective Mycobacterium tuberculosis (Mtb) primarily affects the lungs with involvement of other organs causing tuberculosis (TB) in humans. Since the lung-gut axis is bidirectional, and the gut microbiota contributes to metabolic and immune homeostasis, we looked at the…
Yan Liang, Xueqin Yang, Meifeng Liu, Li Ya-zhen, Y. Zhang
…ve the clinical efficacy of levofloxacin combined with anti-tuberculosis drugs in the treatment of pulmonary tuberculosis and explore effective nursing schemes. The 160 patients who had been clearly diagnosed with pulmonary tuberculosis in our hospital were selected as the study …
Huda Yacoob, Nazar Haddad, Dheyaa Al RAbeai, Abdullah M. Jawad
…ciated with a wide range of health problems, one of them is tuberculosis. the aim is to estimate vitamin D serum concentration among patients with tuberculosis at baseline, 2 and 5 months after starting anti-tuberculosis treatment. Methods The study was carried out at the TB Cent…
Budi Yanti1 , Muhammad Amin2 , Ni Made Mertaniasih2
Background: The Beijing sublineage modern Mycobacterium tuberculosis strain is the most dominantstrain in regards to causes of disease progression, extensive lung tissue damage, drug resistance and highoutbreak rates.Methods: Mycobacterium tuberculosis isolates were obtained from…
Fredrick Ogumbo, Ronald Odero, Ben Odhiambo, Patrick Emojong, Albert Okumu, et al.
Mycobacterium tuberculosis infection is one of the leading causes of mortality and morbidity in developing countries and drug resistance remains a challenge. Drug resistance is hastened by point mutations in the bacilli genome and their frequencies vary geographically hence the n…
Seun Nurudeen Akorede, Ayodotun Edward Ajayi, Peter Oluwatimilehin Tawose
Globally, tuberculosis (TB) constitutes a significant public health emergency. Despite the downward trend in TB incidence and prevalence, every continent still reports new cases, especially Africa and south-east Asia (WHO, 2012). This study aimed to investigate the signs, symptom…
Erwin Astha Triyono, M Festy Mahanani, Sulvy Dwi Anggraini, Hafidh Maulana, Wahyu Dian Pratiwi, et al.
Background: Tuberculosis (TB) is still one of the major health problems in the world, especially in countries with dense populations. Indonesia is listed among the top three countries with the highest burden of tuberculosis worldwide. The low coverage of case detection in Indones…
М. Ф. Губкина, I. Yu. Рetrakova, N. V. Yukhimenko, С. С. Стерликова, Yu. Yu. Khokhlovа
…of differentiated approaches to chemotherapy of respiratory tuberculosis in children exposed to isoniazid resistant tuberculosis.Subjects and Methods. 57 children aged 2-12 years were enrolled in the study (the median age made 8 years) all children suffered from active respirator…
World Health Organization
…es the second edition of the WHO consolidated guidelines on tuberculosis, Module 6: tuberculosis and comorbidities, and presents GRADE summary of findings tables supporting recommendations on tuberculosis and undernutrition. The publication compiles evidence from systematic revie…