Showing 126–150 of 200 documents
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Olajumoke Tubi Abiola, S. D. Gyar, Yakubu Boyi Ngwai, Jibril Egwu Owuna
Abstract Background: Tuberculosis (TB) remains a significant public health challenge in Nigeria, particularly with the emergence of drug-resistant strains. Accurate detection of Mycobacterium tuberculosis (MTB) and its resistance patterns is essential for effective disease manage…
A. Saravanakumar, R. Gandhimathi
Tuberculosis had been a stubborn disease that human beings are combating with from ages. It is a disease that affects the pulmonary system, basically the trachea and upper respiratory organs. It is caused by bacteria called Mycobacterium tuberculosis. Bacteria in the respiratory …
World Health Organization
…es and recommendations on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The publication describes WHO-recommended diagnostic tests and testing algorithms for the detection of Mycobacterium tuberculosis complex and resistance to anti-…
Ramesh Prasad Singh, Ankur Kumar, Arjun Lal, Sushil Prasad Mahto
Tuberculosis (TB) remains a leading health problem not only in India but all over the world. India is the country with highest TB burden accounting for one-fourth (25%) of global TB cases. Diagnosis of tuberculosis (Pulmonary and Extra Pulmonary TB) still remains a challenge. By …
World Health Organization
This web annex to the WHO consolidated guidance on tuberculosis data generation and use provides standardized templates and formulae for the reporting of aggregated tuberculosis (TB) surveillance data and the calculation of core indicators. The document is intended to support con…
S Suganathan Soundararajan, Pavithra GB, P Preeti, B Nisha, Srinivasan Vengadassalapathy, et al.
Introduction: The emergence of Multi-drug Resistant Tuberculosis (MDR- TB) is a challenge for global control and prevention mainly in developing countries. Socio-economic conditions, social vulnerability, and behavioral factors to be considered as risk factors in identifying MDR-…
World Health Organization
…es and recommendations on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The publication describes WHO-recommended diagnostic tests for the detection of Mycobacterium tuberculosis complex and resistance to anti-TB medicines, including…
Frank van Leth, Folke Brinkmann, Daniela María Cirillo, Keertan Dheda, Raquel Duarte, et al.
While the incidence of tuberculosis (TB) has fallen steadily within the European Union, the region has by far the highest estimated incidence of multidrug-resistant (MDR)-TB among TB patients [1, 2], which hampers the goal of the World Health Organization (WHO) of TB elimination …
Bitrus Joshua Barde, Joseph Okopi, Isiyaku Ahmadu
While multi-drug resistant Tuberculosis (MDR-TB) remains a threat to the global fight for the elimination of Tuberculosis (TB), HIV coinfection with MDR-TB makes TB management even worse. Previous studies have reported poorer outcomes and staggering high mortality rates among per…
Callistus A. Akinleye, Adekola O. Adekunle, A. Onabule, Olugbenga Adekunle Olowe, Olusoji Daniel
Background: The global pandemic of tuberculosis has left everlasting scars on people’s lives. Drug-resistant tuberculosis is becoming an increasingly serious hazard to public health. With over 240,000 fatalities due to drug-resistant tuberculosis (DR-TB) worldwide, and Nigeria is…
Smita Mohod, Swati Bhise, Prasanna Raut, Bhoomika Choudhary
Introduction: In underdeveloped countries, Tuberculosis (TB) is a major source of morbidity & mortality. For clinical microbiologists, identifying and detecting Mycobacterium tuberculosis (MTB) constitutes as an important hurdle. Thus, to eliminate the disease early and lower…
Nurul Dwi Andriani, Resta Dwi Yuliani
…view and meta-analysis study design using PICO, population: Tuberculosis Patients. Intervention: Risk Factors for HIV Infection, Smoking, and History of Medication. Comparison: no HIV infection, no smoking and no history of medication, Outcome: MDR-TB incidence. The articles used…
Olivier Marcy, MD, PhD, Maryline Bonnet, MD, PhD, Eric Wobudeya, MD, PhD
Despite progress in reducing tuberculosis (TB) incidence and mortality in the past 20 years, TB is a top ten cause of death in children under 5 years worldwide. However, childhood TB remains massively underreported and undiagnosed, mostly because of the challenges in confirming i…
Bandana Panda, Nilma Hirani, Shraddha Dalvi, Ameeta Joshi
…F and FL-LPA, endorsed by WHO for diagnosing drug-resistant tuberculosis. AIM: Evaluation of diagnostic performance of GeneXpertMTB/RIF and FL-LPA in comparison with liquid culture, the “gold standard” for diagnosing pulmonary and extrapulmonary tuberculosis. Methods: In total 29…
Z.I. Pіskur, O.P. Kostyk, M.І. Sakhelashvili, L.І. Pylypiv, O.M. Shvets, et al.
…ion and course of various clinical forms of extrapulmonary tuberculosis (EPTB), the profile of drug resistance of the Mycobacterium tuberculosis (MBT) among children of different ages. Materials and methods. We retrospectively analyzed the medical data of 47 children aged 0 to 1…
Z.I. Pіskur, L.І. Pylypiv, O.M. Shvets, O.P. Kostyk, M.І. Sakhelashvili
Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. The purpose - to analyze the profile of drug resistance of Mycobacterium tuberculosis and clinical features of extrapulmonary re…
Yuhong Liu, Ph.D, Mengqiu Gao, Ph.D
…s linezolid）works to treat adults with multi-drug resistant tuberculosis or rifampicin-resistant pulmonary tuberculosis, in the context of Pretomanid not available in China. It will also learn about the safety of BDL regimen. The main questions it aims to answer are: 1. What is…
Yuko Nakamura‐López, Valencia-Carmona Oscar Daniel, Martínez-Cruz Perla Mónica, Palma-Nicolas Jose Prisco, González-y-Merchand Jorge Alberto, et al.
Tuberculosis (TB) is a re-emerging health problem worldwide. In Mexico, information about genetic diversity and drug resistance of Mycobacterium Tuberculosis complex (MTBc) is limited. Samples from 463 Presumptive TB cases were tested for TB by smear, culture and PCR, from which …
GajananS Gaude, Samskruti Vishwanath
<br>Tuberculosis (TB), due to <i>Mycobacterium tuberculosis</i>(MTB), remains a major public health issue. It causes ill health for approximately 10 million people each year and is one of the top ten causes of death worldwide. For the past 5 years, it has been the leading cause o…
Allah Rakhia, Taj Muhammad Laghari, Muhammad Ayaz Mustufa, Yahya Noori, Rahila Bhutto, et al.
Abstract Background Diagnosis of childhood TB (tuberculosis) is challenging because its symptoms resemble other diseases, very few (less than five) mycobacteria are capable of causing the disease and children do not or rarely expectorate. These peculiar attributes make childhood …
Abdelbagi Eljayli Mohammed, Nadir Abuzeid, Nuha Yousif Ibrahim, Todd M. Osman, Omer Mohammed Ali Ibrahim, et al.
Multidrug-resistant tuberculosis (MDR-TB) is caused by Mycobacterium tuberculosis resisting at least isoniazid and rifampicin. MDR is a major public health threat in Sudan. This is a descriptive cross-sectional and hospital-based study conducted in Kosti teaching hospital, during…
Tawsifur Rahman, Amith Khandakar, Ashiqur Rahman, Susu M. Zughaier, Muna Al Maslamani, et al.
Abstract Tuberculosis (TB) is a chronic infectious lung disease, which caused the death of about 1.5 million people in 2020 alone. Therefore, it is important to detect TB accurately at an early stage to prevent the infection and associated deaths. Chest X-ray (CXR) is the most po…
Fatima Shamla, Bhushan Chaudhari, Suprakash Chaudhury, Daniel Saldanha
ABSTRACT Background: Tuberculosis (TB) significantly impacts global health, especially in India. The link between TB and mental health issues is known but understudied. Depression and anxiety are more common among TB patients. To improve patient wellbeing and treatment outcomes, …
Harikrishnan P.S.
… compoundsfor their in vitro activity against Mycobacterium tuberculosis H37Rv (MTB), multi-drug resistant M. tuberculosis (MDR-TB) and Mycobacterium smegmatis (MC2) using agar dilution method.
Oyeniyi Muhammed, Israel Olukayode Popoola, Muhammed Mubashir B Uthman, Ebenezer Obi Daniel, Taiwo Popoola, et al.
Tuberculosis (TB), a disease that remains preventable and curable, continues to represent a significant global health burden, particularly in regions like Nigeria. In this context, the emergence of drug-resistant strains of Mycobacterium tuberculosis poses an escalating challenge…