Showing 76–100 of 196 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Rebecca F. Baggaley, Carolin Vegvari, Christian Akem Dimala, Marc Lipman, Robert F. Miller, et al.
…untries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines advising which groups to prioritise for screening can be contradictory and implementation patchy. Evi…
Anggi Angelia, Diana V. D. Doda, Aaltje E. Manampiring
… Quantitative research aimed to determine the prevalence of latent tuberculosis among healthcare workers, evaluate preventive measures, and compliance to use PPE among healthcare workers. The objective of the qualitative research was to evaluate management policies and barriers t…
Chaisson R
…tion tuberculosis in individuals infected with both HIV and latent (inactive) Mycobacterium tuberculosis. Current guidelines from the American Thoracic Society and the Centers for Disease Control recommend 6 to 12 months of INH for PPD (purified protein derivative)-positive indi…
Yu Chen, Yaguo Wang, Joy Fleming, Yanhong Yu, Ye Gu, et al.
…with M. tuberculosis (MTB), the pathogen that causes TB and latently infects ∼25% of the global population, may be a risk factor for SARS-CoV-2 infection and severe COVID-19 pneumonia. Objective To determine if latent or active TB increase susceptibility to SARS-COV-19 infection …
Phani V Akella, Rachel Sigler
…ent AMR and Grade 1R acute cellular rejection (ACR) needing treatment with plasmapheresis, intravenous immunoglobulin (IVIG) and steroids. About three weeks post OHT, she developed fever, lactic acidosis, and hypotension. Infectious workup including blood cultures, respiratory pa…
Joseph A Kovacs, M.D.
…HIV also have the lung infection tuberculosis (TB). Most TB treatments are complicated. A simpler treatment of two TB drugs can be taken once a week. Researchers want to study how the HIV and TB drugs affect each other so people who take both can be treated safely. Objective: T…
Kendra Brett, Melissa Severn
…ency in the majority (i.e., around 95%) of people, known as latent TB infection. People with latent TB do not have any symptoms, and cannot spread the TB infection to others, however, they can develop active TB disease., Active TB disease occurs when the TB bacteria overwhelm the…
Lana Fadl, Arowa Abdelgadir, Hendy Mirza, Aqsa Mahreen, Siddalingana Gouda
…cept, golimumab, and infliximab—are recommended for severe, treatment-resistant AS. Adalimumab, a monoclonal anti-TNF-α antibody, has been linked to a higher tuberculosis (TB) risk than etanercept, with literature suggesting a three- to fourfold increase. We present a rare case o…
María Elvira Balcells, MD; MSc
…exposure within the household, during the first weeks of TB treatment initiation of the index case, can reduce new TB infections in close contacts. For this purpose, a pilot, controlled, pre-post study will be set up, to evaluate the feasibility of implementing a bundle of respir…
Yu Bai, Y. Xue, Mucong Li, Mengtao Li, Chanyuan Wu
…rom approximately 1.2 to over 5, depending on disease type, treatment exposure, and regional TB burden.[3,4] Beyond absolute prevalence, longitudinal data further highlight the sustained and cumulative risk of TB over time in RMD cohorts. Population-based studies from Sweden have…
Gisele Meinerz, Cynthia Keitel da Silva, Damaris Mikaela Balin Dorsdt, Julia Bertoni Adames, Julio Pasquali Andrade, et al.
… infectious complication after kidney transplantation (KT). Latent tuberculosis infection (LTI) screening and treatment is fundamental to prevent post-transplant active disease. Methods: We described a cohort of adult KT recipients from April 4th, 2014 to October 31st, 2018, with…
Jyoti S. Mathad, MD, MSc
…ted and HIV-1-uninfected pregnant and postpartum women with latent tuberculosis (TB). TB is a major cause of illness and death in women of reproductive age. Pregnant and postpartum women with latent TB are at higher risk of developing active TB. This study evaluated the pharmaco…
ASST Fatebenefratelli Sacco
…(hepatotoxicity) in adults treated for tuberculosis (TB) or latent tuberculosis infection (LTBI) and to understand which factors increase this risk. The study also aims to describe how hepatotoxicity is managed in real-world clinical practice and whether treatments such as cortic…
Stefania Cheli
…d prevent the occurrence of DILI and develop more effective treatments. Tuberculosis (TB) is the world's second leading cause of death from a single infectious agent in 2022, after COVID-19. In 2022, TB disease was estimated to affect 10.6 million people, of whom 1.3 million die…
Cheng Chen, Leonardo Martínez, Biao Xu
…d predict the risk of progress to TB disease in people with latent tuberculosis infection (LTBI). Recently, human genetic, immunological and metabolic biomarkers have been considered having promising prospects in monitoring and predicting TB risks qualitatively and quantitatively…
Steven M Holland, M.D.
…in actively recruiting individuals with TB for research and treatment studies. Objectives: \- To collect blood and other samples to study the natural history of tuberculosis. Eligibility: \- Individuals 2 years of age and older who have either active or latent tuberculosis. …
Phool Iqbal, Ashraf Tawfiq Soliman, Vincenzo Desanctis, Mohamed A. Yassin
…e. Tyrosine kinase inhibitors (TKI) are the mainstay of the treatment to achieve remission, while bone marrow transplant is the only proven cure. Tuberculosis (TB), both active and reactivation of latent TB, remains the most common infectious disease worldwide and leads to high m…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
…ganization (WHO) recommends improving access to testing and treatment of latent TB infection (LTBI) [1]. Despite recent epidemiologic studies demonstrating an approximately twofold increased risk of active TB in peripartum women [2], and poor outcomes associated with TB during pr…
Bhumika Harishkumar Bhavsar, Vipul D. Prajapati, Dhaiwat Shukla, Supriya Malhotra
… for autoimmune diseases, raises concern about reactivating latent tuberculosis (TB) and new-onset TB. Despite its established efficacy in managing inflammation, clinicians must recognize and manage adalimumab-induced TB promptly to minimize associated morbidity. This case report…
Nisha Yadav, Sushant Satish Mane, Jyothi Janardhanan, Manas Pustake, Gazi Israil Khan, et al.
of hospital stay in COVID-19 patients with TB, and treatment of COVID-19 in TB. Materials a n d Methods Study DesignA retrospective observational study was done at a tertiary care hospital in Mumbai, India.Children with TB and those without TB were enrolled in the study.According…
Mariana Baptista Angeluci, Marilda Aparecida Milanêz Morgado de Abreu, Ana Cláudia Cavalcante Espósito, Eduardo Vinícius Mendes Roncada, Cristhiana Kise Saito, et al.
…ts and, consequently, increases the risk of reactivation of latent infections, such as tuberculosis (TB). 2 Recent guidelines recommend carrying out TB screening before starting treatment with any immunobiological agent, using the tuberculin skin test (TST) or interferon gama rel…
Dibash Kumar Das
…checkpoint inhibitors (ICIs) have been revolutionary in the treatment of various cancer types, demonstrating favorable outcomes and having been generally well-tolerated by patients with cancer compared to cytotoxic therapy (Front Oncol 2021; doi: 10.3389/fonc.2021.625872). ICIs e…
Jorge Cardenas, Maria E. Campos-Bonaguro, Jacques Simkins
…than 80% of active TB cases arise from previously untreated latent tuberculosis infection (LTBI),3 hence preventive strategies are paramount. In light of the significant burden that TB may inflict in this population, routine screening for LTBI in liver transplant candidates (LTCs…
Andrea A Howard, MD
…, transferred out); TB (tuberculosis) screening results; TB treatment (yes/no); TB treatment outcomes (if applicable); and retention in HIV care. A measurement cohort of 500 HIV-infected patients initiating IPT on or after July 1, 2013 will be recruited from the 10 clinics (n=25…
Gavin Churchyard, MBBCh, PhD
…n most high burden tuberculosis (TB) countries. In its 2015 guidelines, WHO includes 3HP as an latent tuberculosis infection (LTBI) treatment option for high-income and upper middle-income countries with TB incidence rates \<100/100,000. One trial comparing 3HP to 6H in a high bu…