Showing 26–50 of 200 documents
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John C. Mgogwe, Balthazar Nyombi, Oliva S. Massay, Hadija Semvua, Jaffu Chilongola
…lti Drug Resistant Tuberculosis TB (MDR-TB) with or without HIV infection, undergoing treatment with second-line Anti TB plus ARV’s or second-line anti TB. Objective To assess the hematological, biochemical and immunological indices of patients with or without HIV-MDR-TB at the K…
Banubi, G. Vijaya Lakshmi
… the world, mainly in developing nations, co-infection with HIV and tuberculosis (TB) is a significant public health concern. Commonly HIV-TB co-infection is related to a lack of knowledge on TB among people surviving with HIV. Hence, the particular research study is done to know…
I. L. Okoroiwu, Emmanuel Ifeanyi Obeagu, Queen Braxton N. Anaebo, Olivia Walter
Background: Human immunodeficiency Virus (HIV) and Tuberculosis (TB) are the leading infectious diseases with high morbidity and mortality in the developing countries; it has been known to be associated with some coagulation abnormalities especially as the disease progresses.�…
Surendra K Sharma, MD, Ph.D
…ifampicin in antiretroviral naive patients co-infected with HIV and TB and to investigate whether Rifampicin co-administration in clinical practice leads to a clinically relevant decrease of Nevirapine plasma concentrations in Indian patients co-infected with HIV and Tuberculosis…
Liverpool School of Tropical Medicine
…n one primary health care centre in Blantyre, Malawi, where HIV and TB are major contributors to early mortality. Participants will be adults with symptoms of tuberculosis (cough of any duration) attending the primary clinic with an acute care episode. We will exclude adults who…
Linda Gail Bekker, MBChB, FCP, PhD, James McIntyre, MBChB, MRCOG
…e Town, South Africa, a community with high rates of TB and HIV. This study will also examine the genetics of TB and the relationships among active TB infection, new HIV infections, and HIV disease progression. TB is the most common opportunistic infection and the single most co…
Vidya Mave, Samyra R. Cox, Akshay Gupte, Jonathan E. Golub
…tuberculosis (TB) and 662,000 (6%) of them were living with HIV. Over the same period, an estimated 1.1 million people died with TB, and HIV co-infection contributed to an additional 161,000 TB-related deaths [1]. Since 2010, global TB incidence and related mortality have been gr…
Geofrey Ssekalembe
…lic health threat and main causes of death in patients with HIV infection. The risk of developing TB is between 20 and 37 times greater in people living with HIV than among those without HIV. Surabaya city ranks with the highest number of TB and HIV-TB patients in East Java. TB t…
Royce, Sarah, Anglemyer, Andrew, McCarthy, Erin, World Health Organization
R. K. Mishra, Amar Prakash Garg, Tungvir Singh Arya
…roduction: The co-infection of Human Immunodeciency Virus (HIV) and Tuberculosis (TB) presents a signicant public health challenge in India. This paper investigates the quality of life (QOL) and psychosocial factors affecting individuals with HIV alone and those with HIV-TB co-…
Indana Eva Ajmala, Laksmi Wulandari
TB and HIV have a very close relationship since the development of AIDS. Through a significant reduction in cellular immunity, HIV affects the pathogenesis of tuberculosis, thereby increasing the risk of TB in HIV co-infected individuals. In 2006, there were an estimated 9.2 mill…
O. V. Chizhova, Evgeny Belilovskiy, Borisov Se, M. V. Sinitsyn
…e incidence of TB death cases in the presence or absence of HIV infection is different. <b>Aims:</b> Assessment of the presence of seasonal differences in mortality depending on the presence of HIV infection <b>Methods:</b> TB associated monthly deaths of TB/HIV+ (926) and TB/HIV…
Dickens Onyango
…osis (TB) and infection with human immuno-deficiency virus (HIV) are leading infectious causes of morbidity particularly in sub-Saharan Africa, which is disproportionately affected by the two epidemics. Kenya is one of the 30 countries with the highest HIV and TB burden in the wo…
Alex R. Ario, Lilian Bulage, Yvette Wibabara, Peter Muwereza, Daniel Eurien, et al.
Despite remarkable progress in controlling HIV and TB, Uganda is one of the 30 high-burden TB/HIV countries. Approximately 53,000 Ugandans had a new HIV diagnosis in 2019, and approximately 88,000 Ugandans had a TB diagnosis in 2020. Fellows in the Uganda Public Health Fellowship…
Hitender Gautam, Bhanu Mehra, Monika Matlani, Deepti Rawat, Preena Bhalla
BACKGROUND: Human immunodeficiency virus (HIV) and tuberculosis (TB) epidemics continue to fuel each other and with dual infections with these two deadly diseases on the rise, it becomes imperative to devise effective HIV-TB collaborative strategies. The present study was designe…
Titi Supriati, Yodi Mahendradhata, Ari Probandari
…ed services, including diagnostic screening and care for TB-HIV patients. Kulon Progo seeks to improve services under existing health system resources, and it is very important to understand its capacity to provide integrated TB-HIV services. Objective: This study aims to assess …
Roza Kurniati, Dwitya Elvira, Rido Wandrivel
…ckground: Tuberculosis is the most common cause of death in HIV patients. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that plays a crucial role in the immune response to TB and HIV infection. Increased plasma IDO1 activity in TB patients can be a promising marker for the di…
Human Sciences Research Council
…ing intersecting epidemics of human immunodeficiency virus (HIV) and tuberculosis (TB). Among people living with HIV, TB is the predominant cause of death. Since 2002, South Africa has conducted six national population-based HIV surveys, and its first national TB prevalence surve…
Human Sciences Research Council
…ing intersecting epidemics of human immunodeficiency virus (HIV) and tuberculosis (TB). Among people living with HIV, TB is the predominant cause of death. Since 2002, South Africa has conducted six national population-based HIV surveys, and its first national TB prevalence surve…
Ayiguli Alimu, Li Li, Zhong Xueme, Hui Gong, Abudureheman Zulipikaer, et al.
…sure that patients with Acquired Immunodeficiency Syndrome (HIV) and active tuberculosis(TB) co-infection (HIV-TB) can get timely treatment, we investigated T helper cells17 (Th17), Tregulatorycells(Treg) levels in the peripheral blood mononuclear cells (PBMCs) of the TB, HIV, HI…
Andrea A Howard, MD
…, with the ultimate goal of improving health outcomes among HIV-infected TB patients in Lesotho. The study is a two-arm cluster randomized trial, randomized at the TB/HIV clinic level, which includes twelve TB/HIV clinics in Berea district. Clinics are randomized to deliver the c…
Case Western Reserve University
… infection in children. Study participants will include 300 HIV-infected (HIV infection is a viral infection that causes disease which destroys the body's ability to protect itself from infection and disease.) children and 500 HIV-uninfected children, ages 3 months to 5 years, re…
Djatnika Setiabudi, Citra Cesilia, Almira Aliyannissa, Heda Melinda Nataprawira
…ackground Studies about virologic and immunologic status of HIV children are lacking. Tuberculosis (TB) is the most common opportunistic infection in HIV patients and co-infection is associated with much worse prognosis.
 Objective To describe the virologic and immunologic s…
Harmeet Pal Singh Dhooria, Anna Gupta, Gurdeep Singh Dhooria, Deepinder Chhina, Akashdeep Singh
Tuberculosis and HIV together have been referred to as the "cursed duet" and HIV has been found to reduce the effectiveness of treatment of TB. The aim of the study was to determine the status of HIV infection in patients of Tuberculosis and compare with patients of TB infection …
Anthony Garcia-Prats, MD, Ethel Weld, MD
…imen (OBR) for multidrug-resistant tuberculosis (MDR-TB) in HIV-infected and HIV-uninfected children with MDR-TB. The purpose of this study is to evaluate the pharmacokinetics, safety, and tolerability of the anti-TB drug DLM in combination with OBR for MDR-TB in HIV-infected an…