Showing 1–25 of 200 documents
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Pankaj Gupta, Lalit Nainiwal
Background: Tuberculosis is deadliest disease killing nearly 2 million people every year. Before the etiologic cause of TB was determined by Koch, cod liver oil and sunlight, both sources of vitamin D, were used in treatment of tuberculosis. After discovery of antibiotics, anti-i…
Venkateswari Ramachandra, Usharani Brammacharry, Aaina Muralidhar, Anbazhagi Muthukumar, Revathi Mani, et al.
…stic tool capable of simultaneously detecting Mycobacterium tuberculosis and rifampicin resistance. This study aimed to assess the diagnostic precision of GeneXpert MTB/RIF assay to detect pulmonary and extrapulmonary tuberculosis and evaluate the performance for detecting of rif…
Venkateswari Ramachandra, Usharani Brammacharry, Aaina Muralidhar, Anbazhagi Muthukumar, Revathi Mani, et al.
…stic tool capable of simultaneously detecting Mycobacterium tuberculosis and rifampicin resistance. This study aimed to access the diagnostic precision of Xpert MTB/RIF assay to detect pulmonary and extra-pulmonary tuberculosis and to evaluate the performance for the detection of…
World Health Organization
This web annex to the WHO operational handbook on tuberculosis, Module 3: Diagnosis, provides technical guidance for culture-based drug susceptibility testing (DST) of anti-tuberculosis drugs used in the treatment of tuberculosis. The manual describes standardized phenotypic DST …
Anita Nur Charisma, Winariani Koesoemoprodjo
Background: Tuberculosis (TB) in extra-pulmonary organs, such as bone and joint TB, has an incidence rate of 19% of the cases and represents 11-15% of all extra-pulmonary TB. The predilection of bones and joints is the most common predilection with more than 10% of the cases. Gon…
Rafael Laniado-Laborı́n
Although the underlying general principles of management of tuberculosis are the same for all cases, there are certain special situations in which the treatment regimen must be modified. Uremia and post-renal transplant are both risk factors for tuberculosis due to the underlying…
Jiaxing Tan, Yan Yin, Guang Hua, Lili Wang
…agnostic value of T-cell enzyme linked immunospot assay for tuberculosis infection during the diagnosis of pulmonary tuberculosis and extrapulmonary tuberculosis. The study objects were 200 cases of tuberculosis patients in the outpatient department or inpatient department of our…
Pham Dinh Dong, Nguyễn Kim Cương, Nguyen Thi Phuong, Nguyễn Ngọc Hồng, Nguyễn Văn Hùng, et al.
…ional TB Program has made great efforts to detect and treat tuberculosis. Objectives: Assessment of Mycobacterial level in sputum before treatment, and susceptibility to the first line anti-TB drugs of M. tuberculosis strains isolated from TB patients with AFB (+) and non-multidr…
Dorota Sokół, Arkadiusz Standyło, Jakub Czarnota, Tomasz Skubel, Michał Dobrzyński, et al.
…z-Szczęsna Halina. </strong><strong>The correlation between tuberculosis and diabetes incidence and the impact of mass migration on the development of tuberculosis and drug-resistant tuberculosis on the example of India and England</strong><strong>. </strong><strong>Journal of Ed…
T. Nanthini, Karaline Karunagari
Tuberculosis is an infectious disease which spreads from one person to another which has a devastating impact on the economic well-being of the individual, their families, and the entire community. The effective engagement of all health care providers especially nursing personnel…
B. Abdullahi, M.A. Shaibu, A.U. Jibrin
Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the most ancient chronic infectious illnesses and the second greatest cause of infectious death worldwide, behind COVID-19. This study was conducted at the National Tuberculosis and Leprosy Training Center…
Amanda Mabhula
Tuberculosis (TB) is the leading cause of death due to a single infectious disease and remains a major threat to global public health. The increasing emergence of multi-drug resistance to current anti-TB drugs, exacerbated by the long treatment duration, highlights the need for n…
Asheley Henrique Barbosa Pereira, Claudia A.A. Lopes, Thalita A. Pissinatti, A. Pinto, Daniel R. Oliveira, et al.
…ct Herein we present the pathological findings of different tuberculosis stages in Old and New World monkeys kept under human care in Rio de Janeiro, Brazil and naturally infected with Mycobacterium tuberculosis Complex. Fifteen nonhuman primates from five different colonies were…
Salman Khan, Nadeem ur Rehman, Mohammad Zubair, Nisar Khan
Abstract Background: Multidrug-resistant tuberculosis (MDRTB) is a growing global health concern that is a chronic danger to world health due to tuberculosis (TB). Objective: The aim of this study was to examine the frequency of both pre extensively drug-resistant tuberculosis (P…
Berlian Beatrix Rarome, Nurul Aisah, Retno Asih Setyoningrum, Ni Made Mertaniasih
The diagnosis of childhood tuberculosis remains a challenge worldwide. The GeneXpert MTB/RIF test, a rapid Mycobacteria tuberculosis diagnostic tool, was recommended for use in children. No pediatric studies of GeneXpert MTB/RIF assessing pulmonary tuberculosis within a hospital …
Joshua Rosenheim, Markos Abebe, Mulugeta Belay, Begna Tulu, Dawit Tayachew, et al.
Human exposure to Mycobacterium tuberculosis (Mtb) is thought to result in a spectrum of outcomes including bacillary clearance, quiescent Mtb infection, incipient tuberculosis, subclinical tuberculosis and active tuberculosis [1]. Incipient tuberculosis - defined as a prolonged …
Divya Dayal
Background of the Study: Tuberculosis is a global public health issue despite the discovery of the causal bacterium over 100 years ago and availability of effective medications and vaccines for prevention and cure. Tuberculosis has a global incidence rate of 119 per lakh, with lo…
Adane Bitew, Solomon Bati
…y mycosis is increasing and often misdiagnosed as pulmonary tuberculosis in developing countries where the prevalence of pulmonary tuberculosis is high. Objective: To determine the prevalence of pulmonary mycosis and pulmonary tuberculosis fungal co-infections. Methods: A hospita…
М. А. Плеханова, В. А. Аксенова, Л. А. Кривцова
…ctive: to determine predictors of the development of latent tuberculosis infection (LTBI) and tuberculosis in children and adolescents. Subjects and methods . A study was carried out, including testing induced IFN-y and assessment of genotypes of the polymorphic variant of IFNG g…
Agus Khoirul Anam
Abstract: Tuberculosis is an infectious disease caused by germs of a group of mycobacterium namely mycobacterium tuberculosis. The objective of the research is to identify Tuberculosis patients complaints in side effects of drug treatment anti-tuberculosis and factors that influe…
Anand Kumar, Aparjot Singh, Sudhir Chaudhri, Sanjay Kumar Verma, Kiran Pandey, et al.
Background: Mycobacterium tuberculosis, most commonly, infects the lungs (pulmonary TB). Most cases of female genital TB (FGTB) are found in premenopausal women, theoretically because an atrophic endometrium provides a poor milieu for mycobacterial growth. Female genital TB gener…
World Health Organization. Regional Office for Europe
…Region has the highest rates in the world of drug-resistant tuberculosis and increasing rates of HIV/tuberculosis coinfection. Eighteen high-priority countries have been identified to urgently scale up tuberculosis control interventions: Armenia, Azerbaijan, Belarus, Bulgaria, Es…
Krunal Patel, Kinjal Patel, Pooja Gandhi, Bhavini Rathwa, Dipak M. Nakum
Introduction: Tuberculosis is a chronic infectious disease caused by predominantly Mycobacterium tubercle bacilli. Pediatric tuberculosis is among the top 10 causes of death in children. India accounts for one fourth of the global tuberculosis burden, standing one among the thirt…
World Health Organization
…d edition of Module 6 of the WHO consolidated guidelines on tuberculosis, focusing on tuberculosis and undernutrition. The document summarizes evidence on nutritional interventions and micronutrient supplementation for people with tuberculosis receiving treatment, as well as inte…
Anagoni Srikar, B. V. Ramana, Parnakshi Sarma, Alladi Mohan, Abhijit Chaudhury
Abstract Background: Multidrug-resistant tuberculosis (MDR-TB) is a global public health problem. Methods: We tested 104 strains each of Mycobacterium tuberculosis complex ( Mtb ) isolated from new cases and previously treated cases against four first line anti-tuberculosis agent…