Showing 1–25 of 26 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Nirajan Niroula
The study of tuberculosis (TB) pathogenesis has benefitted from the use of animal models like mice, guinea pigs, rabbits, and non-human primates (NHPs). Except for NHP, most animal models have limitations mimicking different aspects of human TB. We propose that the domestic pig, …
Bwarenaba B Kautu
Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). Currently, it is the leading infectious disease killer in the world ranking above HIV/AIDS. Furthermore, the continued emergence and spread of drug-resistant forms of TB are i…
Erick Wekesa Bunyasi
…lthough adolescents have the highest force of Mycobacterium tuberculosis infection1 and rapidly increasing burden of tuberculosis (TB) disease through 10–19 years of age,2 there are few studies on adolescent Mycobacterium tuberculosis infection, transmission, and TB disease in th…
Sarah Ann Elisabeth Rupprechter
…equent adverse reaction to the antimicrobials used to treat tuberculosis, resulting in reduced treatment effectiveness, incomplete treatment, relapse and the development of antimicrobial resistance. The aim of the studies in this thesis were threefold, to investigate biomarkers o…
Kendyl Marie Berry
Osteoarticular tuberculosis (OAT) is a bone degenerative disease that results in bone erosion, joint effusion, joint swelling, and sometimes, nerve compression. OAT occurs from the hematogenous dissemination of Mycobacterium tuberculosis (Mtb) bacilli spreading from the primary s…
Jad Shedrawy
<p>Introduction: The burden of tuberculosis (TB) in Sweden is concentrated among migrants from high TB incidence countries. The incident cases in Sweden arise mainly through reactivation of a latent tuberculosis infection (LTBI) acquired in the home country or during transi…
Maria Norrby
<p>Sweden is a low burden country for tuberculosis (TB). New cases occur mainly among immigrants from countries with a higher TB prevalence. Most persons infected with TB (latent TB) will not develop disease (active TB). Prolonged treatment is necessary and can cause severe…
Khalil Al-Ismail
Background: To estimate the prevalence of latent Pulmonary Tuberculosis infection among healthcare workers in Communicable Disease Center (CDC) in Qatar and explore the factors associated with latent tuberculosis infection LTBI. Methods: A retrospective cohort study was carried o…
Oladokun, Ajibola Samson
… two billion people globally are believed to harbour latent tuberculosis infection (LTBI), which is a precursor to active tuberculosis (TB). Immunocompromising conditions, such as human immunodeficiency virus (HIV) infection, diabetes, chronic renal failure, and chemotherapy, are…
Sarah A. MacLean
The current, most widely used method to screen for latent tuberculosis infection is the Mantoux tuberculin skin test, where tuberculin is injected into a patient's arm and may result in a cutaneous induration forming at the site of injection. A diameter measurement of the resulta…
Suthirote Meesawat, Suchinda Malaivijitnond, Saradee Warit
…mans and wildlife, is increasing during the global warming. Tuberculosis (TB) is an air-borne infectious disease that can be transmitted from humans to non-human primates (NHPs), however, no report of TB prevalence in free ranging NHPs that highly interacted with humans in Thaila…
Inês Alexandra Cesário e Araújo
Tuberculosis (TB) is a disease caused by a group of genetically related bacteria known as the Mycobacterium tuberculosis complex (MTBC) and causes 1.6 million deaths yearly. The TB granuloma is the hallmark cellular structure of latent TB that contains the spread of infection. Mo…
Yi Chu Liang
Tuberculosis (TB) remains a top 10 cause of death globally, with its causative agent Mycobacterium tuberculosis (Mtb) being the single deadliest infectious agent. The immune response is often unable to effectively fight Mtb infection as the bacteria is adept at manipulating and e…
Nurul Adila Mohammed
Tuberculosis (TB) is an old, infectious disease scourge caused by \nMycobacterium tuberculosis (M.tb) that affects human. There are several laboratories \ndiagnostic methods available for TB screening such as sputum smear microscopy, \nculture and nucleic acid amplifi…
Jalal Miah
…reasing burden of diabetes mellitus (DM) posing a threat to tuberculosis (TB) control globally. The global estimate of DM is expected to reach 592 million by 2030. In Europe, the estimated prevalence of DM is 8.5% and the rate of TB is 40 cases per 100,000 persons, with 74, 000 n…
Andrea Bell
Background: San Diego County’s tuberculosis (TB) incidence rate is nearly double than the national rate. In 2019, there have been 5 cases of active TB in the county’s public high schools, which have demonstrated the need for prevention interventions in this setting. Objectives: T…
Sarah Williams
Background: San Diego’s Tuberculosis (TB) incidence is more than double the national rate. The majority of cases of active TB are due to the progression of latent TB infection (LTBI). Objectives: This evidence-based practice (EBP) project aimed to increase knowledge, awareness, a…
Isaac Mwangi Wangari
…, a simple basic model mimicking transmission mechanisms of tuberculosis (TB) is proposed with the aim of correcting problems that are often repeated by mathematical modellers when determining underlying bifurcation structures. Specifically, the model makes transparent the proble…
Christopher Pease
Background: The incidence of tuberculosis (TB) among Inuit is over 400 times that of Canadian-born non-indigenous people. To address this, more patients will need to complete preventative treatment. Methods: First, data were extracted retrospectively for all patients with a tuber…
Melinda Munang
Tuberculosis (TB) is a public health priority in urban cities of high income countries such as the UK, where the local incidence can be several times that of the national incidence. A large dataset of 63,620 individuals registered at a single centre in Birmingham, UK captured all…
Hannah Alsdurf
On estime que près d’un quart de la population mondiale sont infectée avec la tuberculose latente (ITL). Parmi eux, entre 5-15% vont continuer à développer la tuberculose active. En 2015, l’organisation mondiale de la santé (OMS) a défini la stratégie de la lutte contre la tuberc…
Català Sabaté, Martí
…e two infectious diseases that have the greatest impact are tuberculosis (TB) and coronavirus disease 2019 (COVID-19). According to the World Health Organization, TB killed 40 million individuals in the last 20 years. The COVID-19 pandemic has had an overwhelming effect on human …
Cabrera Cortada, Julia
… aim of this project is to progress in understanding Latent Tuberculosis Infection (LTBI) through studying the formation of granuloma in the pulmonary secondary lobe. A reaction-diffuson model has been developed to study the evolution of an initial infection until it is encapsula…
Augustinas Baušys
Prevalence of latent tuberculosis infection, incidence of active tuberculosis infection, risk factors and the value of diagnostic methods in people with human immunodeficiency virus in Lithuania
S. Muñoz Sánchez
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach. This is largely due to the diversity of the causative agent <em>Mycobacterium tuberculosis</em> (<em>Mtb</em>), as well as the variability in host response…