Showing 76–100 of 200 documents
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Vallejo Janeta, Alexander Paolo
Mycobacterium tuberculosis is the principal causative agent of pulmonary tuberculosis. It constitutes a serious public health problem worldwide, especially in developing countries (e.g., Ecuador) where control strategies are scarce or inefficient. Some strains of this pathogen ha…
Akhirunnesa Mily
<p>Even in the 21st century, tuberculosis (TB) remains a major global health threat, primarily due to the emergence of antibiotic resistance. Presence of co-morbidities such as diabetes mellitus (DM) has worsened the current situation and made it more difficult to treat thi…
Frederick Haraka
… early treatment are key in achieving global targets to end tuberculosis (TB). Between 2000 and 2017, nearly 54 million deaths were averted due to timely diagnosis and treatment initiation. Xpert MTB/RIF (“Xpert”¸Cepheid, Sunnyvale, CA, US) is a molecular diagnostic test with int…
Emily J. Mason
<p><b>Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacteria tuberculosis (Mtb). In 2021 over 10 million people were diagnosed with TB. It is the number two cause of death behind COVID-19, being attributed to 1.6 million deaths in 2021. Althou…
Xoliswa Nomvungu
Introduction Tuberculosis (TB) is a common opportunistic infection that occurs more often in people living with human immunodeficiency virus (HIV) because of their weakened immune system, thus increasing their risk of contracting tuberculosis. In the year 2010 isoniazid was intro…
N Kaviya
BACKGROUND: Despite continuous and varied efforts, Tuberculosis has come back with a vengeance in various parts of the world”. Multiple investigation techniques were available for the diagnosis of abdominal tuberculosis including ultrasonography, CT abdomen, Capsule endoscopy and…
Nazifah Ariffin
Tuberculosis (TB) is one of the greatest health care problems in the world. Traditional diagnostic techniques based on the isolation of the tuberculosis bacillus in culture media are time consuming, and it is necessary to wait for several weeks to obtain a result. Therefore, poss…
Amit Gupta, Aditya Anand, Dr. Md Sarfaraz Nawaz, D Haider
Introduction Intestinal tuberculosis-related bowel obstruction is notably prevalent in underdeveloped nations. This study aims to explore the factors leading to suboptimal patient outcomes and to detail the surgical treatments, clinicopathological features, and prognoses of tuber…
Andrea Pirovano
Bovine tuberculosis, a chronic disease caused by Mycobacterium bovis, is a major economic problem affecting farmers both in the UK and worldwide. In order to prevent and control bovine tuberculosis it is very important to be able to promptly and definitively diagnose infected ani…
Chikwaiwa, Belamino K.
…rden TB treatment non-adherence and factors associated with tuberculosis adherence among active age-group patients on tuberculosis treatment at Wilkins Infectious Diseases Hospital and its catchment area. The specific objectives of this study were to assess the prevalence of TB a…
Nonduduzo Magubane, Simangaliso Shangase
Introduction Multidrug-resistant tuberculosis (MDR-TB), which is TB resistant to critical anti-TB drugs such as isoniazid and rifampicin, presents a major challenge to tuberculosis treatment, leading to significant public health concerns. The study objective is to evaluate the pa…
Kenedi Lynch
Tuberculosis (TB), particularly caused by Mycobacterium tuberculosis and Mycobacterium bovis, remains a leading cause of death worldwide, posing significant challenges in both human and veterinary medicine. Control measures are complicated by the disease's latent potential and th…
Miguel Ángel Moreno Molina
[ES] La resistencia a los antibióticos en la tuberculosis es un grave problema de salud mundial y un obstáculo creciente para el control de la enfermedad. En esta tesis utilizamos la genómica como herramienta para estudiar diferentes aspectos de la biología de la bacteria en rela…
Ana Paula Vargas Ruiz
Background: Rifampicin (RIF) resistance in Mycobacterium tuberculosis is frequently caused by mutations in the rpoB gene. These mutations are associated with a fitness cost, which can be overcome by compensatory mutations in other genes, among which rpoC may be the most important…
Mohau S. Makatsa
Tuberculosis (TB) remains the infectious disease causing the greatest global mortality, with an estimated 10 million incident cases of TB and 1.45 million deaths in 2018. Although there is a cure for TB, the success of the treatment is hampered by multidrug resistant TB and HIV i…
P S Kaviyarasi
BACKGROUND: Tuberculosis remains as the most common cause of mortality worldwide. Even after adequate anti tuberculosis treatment many patients have radiological sequelae and respiratory symptoms. AIM OF THE STUDY: The aim of this study is to compare the pulmonary function by spi…
Nadia Baartzes
Malaria and tuberculosis (TB) are infectious microbial diseases contributing to a major global health problem and remain a high priority.The problem is further compounded by the emergence of drug resistant strains of the respective causative agents. New therapies and drug design …
Wang, Chenyang
Tuberculosis is a highly lethal infectious disease, causing approximately 1.5 million deaths annually. Recent years have seen a concerning rise in drug-resistant tuberculosis cases, calling for the development of new approaches for drug susceptibility testing. The conventional go…
Santosh Wagh
Despite decades of research, tuberculosis remains the oldest pathogen-based disease that is the leading cause of death from a single infectious agent. Among many anti-tubercular therapies under investigation, the semisynthetic compounds spectinamides are a promising novel class o…
K Rajarajeswari
BACKGROUND: Tuberculosis remains the single largest infectious disease carrying high mortality in humans. The protective and pathologic response to tuberculosis to mycobacterium tuberculosis is complex and multifaceted involving many components of immune system with excessive pro…
Assel Bukharbayeva
…iency virus diagnosis, lead to increased rates of pulmonary tuberculosis among Kazakhstani population.Our study aimed to estimate the potential modifiable effect of living area on risk factors of pulmonary tuberculosis and estimate the proportion of a disease related to a given e…
Ulanova (Igumnova), Viktorija
…e-size-fits-all approach to a more individualised strategy. Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which is transmitted between humans through the respiratory tract, most commonly affecting the lungs. TB is a major global public hea…
Ziqing Xu, Tepanata Pumpaibool
Tuberculosis (TB) is still a significant global public health concern, particularly in resource-limited countries. Even WHO set the targets of the End tuberculosis (TB) by 2030, the global trend in TB case incidence becomes increase including in Southeast Asian region. The newly …
Ziqing Xu, Tepanata Pumpaibool
Tuberculosis (TB) is still a significant global public health concern, particularly in resource-limited countries. Even WHO set the targets of the End tuberculosis (TB) by 2030, the global trend in TB case incidence becomes increase including in Southeast Asian region. The newly …
Ulanova (Igumnova), Viktorija
…e-size-fits-all approach to a more individualised strategy. Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which is transmitted between humans through the respiratory tract, most commonly affecting the lungs. TB is a major global public hea…