Showing 26–50 of 200 documents
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Arunagiri Pandiyan
INTRODUCTION: According to WHO global tuberculosis report 2018, Worldwide, TB is one of the top 10 causes of death and the leading cause from a single infectious agent (above HIV/AIDS). False-negative results and misdiagnosis of TB suspects are common in developing nations, as mo…
Nicholaus P. Mnyambwa
Tuberculosis remains one of the world’s deadliest infectious diseases in resource-limited settings, including Tanzania. Diagnostic challenges and minimal information on resistant tuberculosis complicate building effective management strategies. The current study employed whole ge…
Chu-Chang Ku
Socioeconomic barriers to tuberculosis care-seeking and costs due to care-seeking lead to unfavourable treatment, epidemiological and economic outcomes. Especially in the post-2015 era, socioeconomic interventions for tuberculosis control are receiving increasing attention. In Ta…
L. J. Wang
Tuberculosis, caused by bacteria in the Mycobacterium tuberculosis complex, is a major global public health issue. The emergence of drug-resistant tuberculosis strains presents an alarming challenge to disease control, casting a shadow over the ambitious elimination goals set by …
L. L. Wang
Tuberculosis, caused by bacteria in the Mycobacterium tuberculosis complex, is a major global public health issue. The emergence of drug-resistant tuberculosis strains presents an alarming challenge to disease control, casting a shadow over the ambitious elimination goals set by …
Nura Mohammad Rabiu Ahmad
Tuberculosis (TB) is an infectious disease that is considered to be the biggest killer of mankind in the history of infectious diseases. There are still more than 10 million new TB cases every year and it causes more than 1.5 million deaths annually, according to World Health Org…
Mota, Bárbara da Silva
A tuberculose, provocada pela Mycobacterium tuberculosis, permanece uma das principais causas de morte devido a um único agente infecioso. A vacina Bacillus Calmette-Cuérin (BCG) representa uma estratégia crucial no combate global contra a tuberculose, contudo, apresenta uma efic…
Themba Mzembe
…espite effective treatment being available since the 1940s, tuberculosis (TB) remains a leading cause of death by a single infectious agent. Continued transmission is one of the driving factors of the TB epidemic. In high TB and HIV prevalent settings Mycobacterium tuberculosis t…
S Rajeev Gayathri
INTRODUCTION: Patients treated with pulmonary tuberculosis are frequently left with sequelae. The resulting parenchymal impairment can cause pulmonary hypertension. But tuberculosis sequelae as a cause of pulmonary hypertension have not been evaluated and remain an unmeasured bur…
Marie Sjölin Wijk
Tuberculosis remains the leading cause of death from a single infectious agent globally, posing a significant threat to public health. This highlights the need for improved treatment strategies to enhance outcomes and limit the emergence of resistance. Optimizing therapy requires…
Nuzulul Laili
Background: Tuberculosis, well-known as TB, was a disease that caused by the bacteria infection of Mycobacterium Tuberculosis. Tuberculosis still became a health issue both in Indonesia and in the world-wide even the World Health Organization (WHO) declared that TB as a global he…
Sarah Ann Elisabeth Rupprechter
…equent adverse reaction to the antimicrobials used to treat tuberculosis, resulting in reduced treatment effectiveness, incomplete treatment, relapse and the development of antimicrobial resistance. The aim of the studies in this thesis were threefold, to investigate biomarkers o…
Hlengiwe N. Mtetwa
… of infectious diseases. This is particularly important for tuberculosis (TB) and multidrug-resistant tuberculosis (MDR-TB), due to increasing globally infections and the associated economic burdens. TB and MDR-TB infections are high in several countries, with South Africa contri…
Justin Tapiwa Shenje
Tuberculous pericarditis is caused by Mycobacterium tuberculosis infection of the pericardium, which is associated with a higher mortality, compared with pulmonary tuberculosis. Constrictive pericarditis, a significant complication of tuberculous pericarditis, contributes to this…
Valerie A. C. M. Koeken
…n of immune cells during host defense against Mycobacterium tuberculosis.Glutamine has been implicated as an immunomodulatory nutrient, but its role in response to M. tuberculosis is unknown. MethodsWe assessed expression of glutamine pathway genes in M. tuberculosis-infected mac…
Parthi Srinivasan
BACKGROUND: Tuberculosis (TB) remains a major health problem across the world and commonly involves the lungs. Analysis of serum adenosine deaminase activity is a very useful diagnostic approach to achieve a more rapid and precise diagnosis in serum of pulmonary tuberculosis. OBJ…
Cristina Kraemer Zimpel
Adaptao de Mycobacterium tuberculosis e Mycobacterium bovis a hospedeiros: uma anlise genmica e transcricional A tuberculose (TB) uma doena causada por bactrias do complexo Mycobacterium tuberculosis (MTBC) que infectam humanos e animais.Membros do MTBC possuem evoluo clonal, por…
Preeti Kundu
<p>Tuberculosis (TB), which is estimated to affect 2 billion individuals worldwide, is an infection predominately caused by Mycobacterium tuberculosis(M. tuberculosis). Of particular concern is the increasing prevalence of TB, which is becoming resistant to the treatments c…
Aristide G. Lambura
Tuberculosis continues to be a life-threatening disease in Sub-Saharan African countries despite the available vaccine whereas soil-transmitted helminth is among the neglected tropical disease that causes threats to pre-school, school-aged children and child-bearing mothers. The …
Dylan C. Farr
…gly important in solving several serious healthcare issues. Tuberculosis (TB) is among one of the world’s most serious health threats, especially in developing countries, and although treatment is available, current methods take 6 – 24 months. Prolonged treatment times often resu…
Olivia Biermann
<p>Background: Tuberculosis (TB) is one of the world’s leading infectious killers. Every year, an estimated 10 million people fall ill with the disease, of whom 2.9 million people are never diagnosed and treated. Thirty low- and middle-income countries account for almost 90…
Preeti Kundu
<p>Tuberculosis (TB), which is estimated to affect 2 billion individuals worldwide, is an infection predominately caused by Mycobacterium tuberculosis(M. tuberculosis). Of particular concern is the increasing prevalence of TB, which is becoming resistant to the treatments c…
C Ashmi
BACKGROUND: Globally extra pulmonary tuberculosis (EPTB) accounts for 25% of all tuberculosis cases. The Gene Xpert MTB/RIF assay is a newly developed, automated diagnostic molecular test recommended by WHO for diagnosing EPTB. In the current situation determination of MDR status…
Peter M. Mbelele
Rifampicin or multidrug-resistant tuberculosis (RR/MDR-TB) accounts for considerable morbidity and mortality. Differences among Mycobacterium tuberculosis complex (MTBC) species may predict drug-resistance or treatment success. This thesis aimed at identifying MTBC at species lev…
Kendyl Marie Berry
Osteoarticular tuberculosis (OAT) is a bone degenerative disease that results in bone erosion, joint effusion, joint swelling, and sometimes, nerve compression. OAT occurs from the hematogenous dissemination of Mycobacterium tuberculosis (Mtb) bacilli spreading from the primary s…