Showing 176–200 of 200 documents
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Poras Chaudhary, Rajeev Kumar, Milind Alokjee, Abhinav Bhalla, Sunny Thakur, et al.
…hare a review of the English-language literature on splenic tuberculosis (TB) to gain a better understanding of etiopathogenesis, epidemiological features, and diagnostic methods and provide guidelines for its management and to present our experience of six cases. **METHODS:** T…
Yichen Li, Jie Cheng, Xinxin Bai, Jie Zheng, Peifang Mao, et al.
…BMI) measured at treatment initiation on mortality rates in tuberculosis (TB). **METHODS:** This PROSPERO-registered PRISMA compliant review searched PubMed, Embase, CENTRAL, and Web of Science for studies from inception upto 10June 2024. Studies on adult patients examining mort…
Hadi Sahrai, Jamal Behnood, Mansoureh Baradaran, Amirreza Khalaji, Ali Norouzi, et al.
…ACKGROUND:** Distinguishing lung cancer (LC) from pulmonary tuberculosis (TB) on CT is difficult. We synthesized evidence on radiomics, clinical, and combined models for LC–TB discrimination. **METHODS:** PubMed, Web of Science, Embase, and Scopus were searched to August …
Kevin Komakech, Derrick Semugenze, Moses Joloba, Frank Cobelens, Willy Ssengooba
**BACKGROUND:** Limited access to accurate and accessible tuberculosis (TB) diagnostics remains a critical barrier to timely diagnosis and care in high burden low- and middle-income countries. Point-of-care (POC) TB Triage tests (POC-TTTs) defined as a test performed near to a pa…
Malika Idayat, Elena von der Lippe, Nailya Kozhekenova, Oyunzul Amartsengel, Kamila Akhmetova, et al.
: In 2023, tuberculosis (TB) caused 1.25 million deaths globally, remaining a leading infectious killer. Central Asia and Southern Caucasus face high TB burdens, particularly Mongolia. This review synthesizes TB prevalence data and diagnostic capabilities in these regions to supp…
Muhammad Abubaker Tobaiqi, Musleh Naser Alshamrani, Shyamkumar Sriram, Ahmad Bakur Mahmoud, Hammad Ali Fadlalmola, et al.
: The world health goal of eliminating tuberculosis (TB) is heavily hinged on timely and efficient diagnosis and treatment. The interferon-γ release assays (I.G.R.A.s) can diagnoseinfection and offer an alternative to the centuries-old tuberculin skin test (T.S.T.). Yet the…
Vega Pangaribuan, Muhammad Arifin Parenrengi, Wihasto Suryaningtyas
…cal presentation and management of pediatric cervical spine tuberculosis (CST) and evaluate the outcomes of conservative or surgical treatment based on anatomical location (craniovertebral junction [CVJ], subaxial, and cervicothoracic junction). **METHOD:** We searched for studi…
Jingru Cheng, Jia Zhu, Ruina Chen, Meiling Zhang, Bing Han, et al.
**BACKGROUND:** Anti-tuberculosis drug-induced liver injury (ATLI) is a significant adverse drug reaction with genetic susceptibility implications. **AIM:** This study aimed to integrate findings from systematic reviews and meta-analyses on genetic polymorphisms associated with …
Hanhan Wu, Yazhen Lang, Luqing Jin, Yanqin Shen, Weiyan Pu, et al.
**BACKGROUND:** Pulmonary tuberculosis (PTB) in childhood can result in persistent lung function impairment in adults, but data among children remain limited. This systematic review and meta-analysis aimed to summarize and update current evidence on pulmonary function outcomes af…
Ramesh Kumar, Abhishek Kumar, Sudhir Kumar
Tuberculosis (TB) is still a major public health issue in developing countries, where it causes a heavy disease burden. Although current anti-TB treatment regimens demonstrate high efficacy, the hepatotoxic potential of first-line anti-TB drugs (ATDs) - particularly isoniazid, ri…
Kacper Borodziuk, Adele H Marshall, Maria J H O'Hagan, Aleksandar Novakovic, Emily A Courcier
Bovine tuberculosis (bTB) is a chronic zoonotic disease, caused by Mycobacterium bovis which despite years of eradication attempts, is still prevalent globally. Machine learning (ML), a technology allowing for computerised discovery of patterns in data, has been applied widely to…
Alireza Firouzjahai, Mahdie Taheri, Siamak Sabaghi, Radmehr Nozari, Samaneh Rouhi, et al.
… play a significant role in the susceptibility to pulmonary tuberculosis (TB). Recognition of these polymorphisms is a crucial aspect of TB treatment. This study aims to investigate the effects of VDR gene polymorphisms on TB susceptibility. **METHODS:** This research encompasse…
Akihiko Goto, Ishikawa Kentaro, Taisei Hirakawa, Kosaku Komiya
Pulmonary tuberculosis (TB) and nontuberculous mycobacterial pulmonary disease (NTM-PD) often present with similar clinical and radiological features, making accurate differentiation essential. This systematic review aimed to summarize diagnostic features that distinguish pulmona…
Jessica Edelyne, Muhammad Prasetio Wardoyo, Luthfiyah Zanida Putri, Salsabila Hulwani, Assica Permata Amalya Hakiman, et al.
**BACKGROUND:** Tuberculosis (TB) remains a leading cause of global mortality, underscoring the need for accessible prognostic tools. C-reactive protein (CRP) is a widely available acute-phase biomarker that may predict outcomes in TB. This systematic review and meta-analysis ass…
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin-Gun Cho, Jan-Willem C Alffenaar
… associated with the new shorter regimen for drug-resistant tuberculosis (TB) containing a bedaquiline-pretomanid-based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by combining safety da…
Prisana Mandeville, Jan M Nick, Fayette Truax, Safiye Sahin, Gurmeet Sehgal
… review aims to investigate the global pooled prevalence of tuberculosis (TB) infection among pregnant women. **INTRODUCTION:** TB infection affects 25% of the global population and poses a significant public health challenge, particularly among pregnant women who are at higher …
Jeffrey I Campbell, Ojasvi Vachharajani, Melanie M Dubois, Leonardo Martinez, Paul J Christos, et al.
… more than 70% of these children live in settings with high tuberculosis (TB) burden. Whether children who are HIV-exposed uninfected (cHEU) are at increased risk of TB infection and disease is debated. **DESIGN:** We performed a systematic review and meta-analysis of TB infecti…
Dawit Gebremichael
Bovine tuberculosis (bTB) has significant economic losses on the livestock productivity and poses serious public health risks worldwide. In Ethiopia, bTB is endemic and distributed across all parts of the country. Therefore, the systematic review aims to provide comprehensive inv…
Denekew Tenaw Anley, Melaku Ashagrie Belete, Ermias Sisay Chanie, Anteneh Mengist Dessie, Melkamu Aderajew Zemene, et al.
Tuberculosis (TB) remains a global health challenge, with drug-resistant (DR) forms of the disease posing a significant threat to effective disease control. Prognostic models are crucial tools that aid in clinical decision-making by predicting the likelihood of adverse treatment …
Nicole A Swartwood, Nanki Singh, Seyed Alireza Mortazavi, Melike Hazal Can, Hening Cui, et al.
**BACKGROUND:** Global and national initiatives to combat tuberculosis (TB) have expanded over recent years. Despite this, the TB burden remains high in some population groups, with men recognized as having elevated TB risks. Summary measures of sex differences in TB prevalence w…
Mary Gaeddert, Penelope Papadopoulou, Jennifer Habbes, Tobias Niederegger, Lukas Schik, et al.
**BACKGROUND:** The diagnosis of tuberculosis (TB) typically relies on being able to produce a sputum sample for microbiological testing. However, sputum scarcity, the inability to self-expectorate an adequate sputum sample for TB testing, is a well-known concern. Our systematic …
Mary Gaeddert, Jennifer Habbes, Julian Meister, Ashlyn Beecroft, Amelie von Saint Andre-von Arnim, et al.
**BACKGROUND:** Tuberculosis (TB) diagnosis typically relies on testing sputum samples, but children often cannot produce sputum. Our review investigated the collection of self-expectorated and induced sputum, and alternative methods of sampling including gastric and nasopharynge…
Xuling Chang, Zheng Li, Phan Vuong Khac Thai, Dang Thi Minh Ha, Nguyen Thuy Thuong Thuong, et al.
**BACKGROUND:** Tuberculosis (TB) continues to be a leading cause of morbidity and mortality worldwide. Past genome-wide association studies (GWAS) have explored TB susceptibility across various ethnic groups, yet a significant portion of TB heritability remains unexplained. **M…
Warinmad Kedthongma, Sopon Usaprom, Wuttiphong Phakdeekul
…:** More than a century of medical progress has not reduced tuberculosis (TB) as a leading global health threat. The challenge is not drug availability but treatment completion. The 10.7 million new cases and 1.23 million deaths reported in 2024 underscore that biomedical solutio…
Jingyuan Feng, Minghao Hu, Hongfei Duan
Tuberculosis (TB) and chronic obstructive pulmonary disease (COPD) are major respiratory diseases contributing to high global morbidity and mortality. Recent studies suggest a potential bidirectional association between them; however, the overall evidence has not been systematica…