Showing 1–6 of 6 documents
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Ajit Lalvani, Clementine Fraser, Manish Pareek
…at M.tb infection, even at very low bacterial burdens as in Latent tuberculosis infection (LTBI), evokes a strong Cell-mediated immunity response to M.tb antigens. LTBI was previously thought to represent a uniform state. However, as research progresses it has become clear that L…
Lynn Sosa, Lloyd N. Friedman
This chapter discusses the guidance on options for treatment recommended by established national and international organizations. Generally, practitioners should follow the guidelines specified by the organization that represents the geographical location of the treatment facilit…
Akanksha Sirohi, Yash Vardhan Trivedi, Tavishi Katoch, Benjamin Walters, Vasu Bansal, et al.
…, focusing on high-risk populations, current diagnostic and treatment strategies, and the importance of addressing clinical and social determinants of health to achieve TB elimination goals.MethodsA review of the latest evidence-based guidelines and literature on TB diagnostics, …
Joseph Sturman, Jyoti Baharani, Jed Ashman, Lorraine Harper, Adam F Cunningham, et al.
…tion in endemic countries. Patients with CKD generally have latent TB reactivation, rather thaninfection, which presents with atypical, non-pulmonary presentations leading to late diagnosis, poorer outcomes and a high risk of widespread transmission through haemodialysis units. T…
Katherine Timboe, J Brooks Jackson, Greta L Becker
…ding infectious cause of death globally. Although effective treatments are available, treatment length, drug toxicity, and the emergence of drug-resistant strains have challenged TB control efforts. Current clinical trials are focused on developing shorter, safer, and more effect…
Lucía Madero, Iria Bastón, Eduard Brunet-Mas, Margalida Calafat, Grupo Joven de GETECCU
…ble risk of TB reactivation. Given this risk, screening for latent tuberculosis infection (LTBI) is essential in IBD patients before initiating immunosuppressive therapy. Guidelines recommend performing this screening ideally at the time of IBD diagnosis or, alternatively, before…