Showing 26–50 of 200 documents
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Kohei Kamegai, Ikumi Ono, Sayaka Kageyama, Kotaro Murata, Shunta Miura, et al.
In December 2024, Japan's Pre-Entry Tuberculosis Screening (JPETS) program was introduced in coordination with the Ministry of Health, Labour and Welfare (MHLW), the Ministry of Foreign Affairs, and the Immigration Services Agency to mandate tuberculosis (TB) screening for mid- t…
Susanna Esposito, Beatrice Rita Campana, Gaia Giorgia Arnesano, Nicola Principi
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide, with children representing a particularly vulnerable population in whom diagnosis is often challenging. Pediatric TB is typically paucibacillary and presents with non-specific clinical manifestations,…
Wiwiek Setiowulan, redi rulandani, Helmy Rachman
…ay and no symptoms of TB. Therefore, the patient has latent tuberculosis infection (LTBI) but overdiagnosed as TB disease. Due to the negative HIV status of the patient, TB prophylaxis is not indicated. Therefore, reintroduction of ATT was contraindicated, which led to lack ident…
Martin Dedicoat
A quarter of the world's population may be infected with tuberculosis (TB). In the majority of these people the infection will remain dormant. A variety of risk factors may lead to this latent TB infection (LTBI) becoming active. Treatment of LTBI has been shown to reduce the ris…
Salma Madihi, Achraf Aainouss, Mly Driss Ei Messaoudi, Abdelouaheb Benani
Tuberculosis (TB) is a major health burden, the leading cause of death among people living with HIV, and one of the main causes of death linked to antimicrobial resistance. The World Health Organization (WHO) launched in 2015 the End TB Initiative that aims to reduce TB cases and…
María Belén Vecchione, Denise Anabella Giannone, Milagros Victoria Acevedo, Natalia Santucci, Maria Florencia Quiroga
**BACKGROUND:** Tuberculosis (TB) remains a leading cause of mortality worldwide among infectious agents, and HIV increases the risk of developing into active disease. HIV-TB coinfection impairs immune responses, while chronic inflammation and infection-associated stress activate…
Yi Hao Wong, Hai Tarng Chong, Ting Huey Hu, Catherine Wei Min Ong
Despite the World Health Organization End TB Strategy, tuberculosis (TB) remains the world's leading infectious cause of death. Conventional antimicrobial therapies are hindered by prolonged treatment durations, poor patient adherence, and drug toxicity. Host-directed therapies (…
Salmaan Keshavjee, T. Nicholson, Aamir J. Khan, Lucica Diţiu, Paul E. Farmer, et al.
…; participants then received treatment for active or latent Tuberculosis (TB) as needed. Local coalitions can use the experiences and framework to inform how to tailor the own efforts to drive down TB rates one community at a time. Additionally, TB is driven by poverty and is its…
Salvatore Rotundo, Francesca Serapide, Gabriella d'Ettorre, Maria Teresa Tassone, Mattia Albanese, et al.
Tuberculosis (TB) remains a significant global health challenge, especially in countries with low TB incidence, exacerbated by the influx of migrants from high TB-burden regions. This paper reviews the challenges and strategies for managing TB infection (TBI) among migrants. Chal…
Francesca Saluzzo, Andrea Maurizio Cabibbe, Richard Anthony, Alexandra Aubry, Francis Drobniewski, et al.
…rted poor treatment outcomes for extensively drug-resistant tuberculosis (TB) in the European region highlight the urgent need for effective and context-appropriate diagnostic strategies. While the World Health Organisation (WHO) provides model algorithms, these require adaptatio…
Yonathan William, Marto Sugiono, Patricia Diana Prasetiyo, Adelbertus Erico, Gilbert Sterling Octavius
…d tuberculous prostatitis. The patient was treated with antituberculosis drugs, resulting in symptomatic improvement and a significant PSA decline. This case highlights the diagnostic challenge of distinguishing tuberculous prostatitis from prostate cancer, particularly in tuberc…
Olga Bilogortseva, Ya. I. Dotsenko
ПЕРЕБІГ ЛАТЕНТНОЇ ТУБЕРКУЛЬОЗНОЇ ІНФЕКЦІЇ У ДІТЕЙ З ВСТАНОВЛЕНОГО ТА НЕВІДОМОГО КОНТАКТУЗ ХВОРИМ НА ТУБЕРКУЛЬОЗ Білогорцева О. І
Phumeza Tisile, Goodman Makanda
<bold>Meaningful partnerships that put TB survivors and people living with TB at the centre of research and policy-making are critical to the elimination of TB</bold> <ext-link>https://bit.ly/ERSM101intro</ext-link>
Aishwarya Venkataraman, Nancy Hilda Joseph, Gopika Sadanandan, S Balasubramanian
Clinical research involving children presents significant challenges due to physiological, ethical, regulatory, and practical considerations unique to this vulnerable population. These intrinsic challenges were amplified during the COVID-19 pandemic, which substantially disrupted…
Anna Starshinova, Ekaterina Belyaeva, Olga Irtyuga, Giunai Sefiyeva, Lubov Mitrofanova, et al.
Tuberculosis remains a serious infectious disease that causes over 1.3 million deaths annually. Following the COVID-19 pandemic, the global incidence of tuberculosis has increased to 10.8 million cases. Pregnant women represent a particularly vulnerable population requiring tailo…
Shayam Kaushik, Savita Krishnamurthy, Neelam Grover, Rajni Kaushik
The study's goal is to examine the range of adolescents tuberculosis. Adolescence is characterised by a substantial increase in the incidence of tuberculosis, a known fact since the early 20th century. Most of the world's adolescents live in low-income and middle-income countries…
Siddharth Sekhar Sethy, Gagan Deep, P V Sudhakar, Tarun Goyal, Pankaj Kandwal, et al.
…cases of extrapulmonary TB. The incidence of osteoarticular tuberculosis is one of the lowest in extrapulmonary tuberculosis, probably only next to cutaneous tuberculosis in non-HIV patients. Considering the low incidence of primary osteoarticular tuberculosis without pulmonary t…
Jingxian Ning, Rong Wang, Yuchen Pan, Xinru Fei, Wenxin Jiang, et al.
**OBJECTIVE:** Tuberculosis significantly affects human health and longevity. We aimed to systematically synthesize studies to summarize the median survival time range and years of potential life lost (YPLL) among tuberculosis patients. **METHODS:** We searched Web of Science, P…
Xinxin Fan, Muxing Chen, Di Wu, Youfei Lin, Xiaohong Chen
According to the 2024 World Health Organization (WHO)Global Tuberculosis (TB)Report, tuberculosis remains the leading cause of death from a single infectious agent, with 10.8 million new cases and 1.25 million deaths in 2023. Early and standardized treatment upon definitive diagn…
Yusup Subagio Sutanto, Magdalena Sutanto, Agnes Sri Harti, Nony Puspawati
This study highlights the sensitivity of Mycobacterium tuberculosis isolates from suspect tuberculosis patients to seromucous of snail and chitosan as an alternative to anti-tuberculosis drugs. This research is based on the results of laboratory experiments. The research stages i…
Balasundaram Revathi Mani, Usharani Brammacharry, Venkateswari Ramachandra, Suganthi Palavesam, Muthuraj Muthaiah
The emergence of drug-resistant tuberculosis jeopardizes the TB control programme activities globally. Multidrug-resistant TB is defined as tuberculosis strains resistant to at least two first-line drugs, rifampicin (RIF) and isoniazid (INH). Extensively drug-resistant TB refers …
Ravi Talapa, Nidhi Yadav, Siddhant Jain, Tanvi Sirohi, Shourya Yerramareddy
Tuberculosis is a disease with widespread character and a long treatment process. Tuberculosis affecting the thyroid gland is a rare occurrence, even in the regions where tuberculosis is prevalent. This case report details the presentation of a 22-year-old male who initially pres…
Md Abdur Rahim, Hoonhee Seo, Indrajeet Barman, Mohammed Solayman Hossain, Md Sarower Hossen Shuvo, et al.
Tuberculosis, primarily caused by, is an airborne lung disease and continues to pose a significant global health threat, resulting in millions of deaths annually. The current treatment for tuberculosis involves a prolonged regimen of antibiotics, which leads to complications such…
Vidya Mave, Mandar Paradkar, Francesca Conradie, Amita Gupta, Anchalee Avihingsanon, et al.
Over the past 80 years, tuberculosis treatment has evolved with the development of all-oral treatments, which are now given for 4-6 months for drug-sensitive tuberculosis and 6-9 months for drug-resistant tuberculosis. Treatment success is often reduced among people with HIV due …
Yu Lan, Isabel Rancu, Melanie H Chitwood, Benjamin Sobkowiak, Kate Nyhan, et al.
Tuberculosis remains a leading cause of infection-related mortality, and efforts to reduce its incidence have been hindered by an incomplete understanding of local Mycobacterium tuberculosis transmission dynamics. Advances in pathogen sequencing and spatial analysis have created …