Showing 151–175 of 200 documents
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Pınar Ergenekon, Arif Kut, Nader Fasseeh
Tuberculosis (TB) is a serious public health problem affecting the entire globe. Despite the fact that Mycobacterium tuberculosis (MTB) vaccine was invented a long time before, MTB is even today one of the most widespread causes of mortality due to a single infectious factor [1, …
Rupak Chatterjee, Sumanta Sinha, Kumkum Sarkar, Debananda Gonjhu, Sekhar Pal, et al.
Tuberculosis has many mechanisms that may lead to hypercoagulable state and can lead to thromboembolic complications. It may be a potentially life-threatening condition. The physician's awarness of this disease condition is important to an early diagnostic suspicion and prompt tr…
Charlotte A. Roberts, Peter Davies, Kelly E. Blevins, Anne C. Stone
Tuberculosis (TB) is a bacterial infectious disease caused by organisms from the <italic>Mycobacterium tuberculosis</italic> complex, <italic>Mycobacterium tuberculosis</italic> and <italic>Mycobacterium bovis</italic> being of most importance to humans. TB is one of the top ten …
Usharani Brammachary, Venkateswari Ramachandra, Suganthi Palavesam, Vidya Raj Cuppusamy Kapalamurthy, Aaina Muralidhar, et al.
Tuberculosis (TB) remains the most challenging infection to treat worldwide. The contemporary TB regimens consist of 6–9 months of daily doses of four drugs in the existing regimen that is extremely toxic to patients. The purpose of these longer treatments is to eliminate Mycobac…
Diwakar Singh
Mycobacterium tuberculosis, which causes TB, is a serious global health problem. Protein kinases are essential for controlling many cellular functions, including the induction of immune response to pathogens. Now a day TB strains that are getting more and more drug resistant is a…
Karolina D. Witt
Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that has co-evolved with humans and developed various decoy strategies to survive in hostile environments by manipulating host immunity to its advantage. This occurs through selective antigen presentation at the cellul…
Fabiana Cristina Fulco Santos, André Luiz Alves do Nascimento, Laís Ariane de Siqueira Lira, Juliana Figueirêdo da Costa Lima, Rosana de Albuquerque Montenegro, et al.
Bone tuberculosis (TB) is one of the forms of extrapulmonary tuberculosis that affects, above all, the spine, long bones and joints. The authors report a case of a 12-year-old child with a complaint of pain and deformity in the lower thoracic region that had lasted for two years.…
Victória Moraes-Silva, Cecília Alvim Dutra, Márcia Quinhones Pires Lopes, Philip Noël Suffys, Adalberto Rezende Santos, et al.
Tuberculosis (TB), mainly caused by Mycobacterium tuberculosis, accounts for 10 million cases worldwide per year, remaining a major problem for public health. The anti-TB drug isoniazid (INH) is recommended by the WHO. Despite of effective drugs, some individuals do not respond t…
Rachana Khati, Alok Kumar Paul, Maria de Lourdes Pereira, Mohammed Rahmatullah, Veeranoot Nissapatorn, et al.
… the ancient period, the pathogenic bacterium Mycobacterium tuberculosis has been affecting mankind and has become a cause of contagious disease—tuberculosis. However, to globally overcome the health issues against MDR and XDR TB, there is an urgency to streamline more inputs for…
Krupanshi Bharadava, Aviral Kaushik, Nigam Vyas, Tarun Kumar Upadhyay, C. Ratna Prabha, et al.
Tuberculosis (TB) is a highly contagious and potentially life-threatening infectious disease caused by the bacterium <i>Mycobacterium tuberculosis</i> (MTB). Despite significant progress in medical science, TB remains a global health concern, affecting millions of peo…
Onix Cantres-Fonseca, William Rodríguez-Cintrón, Francisco Del Olmo-Arroyo, Stella Baez-Corujo
Mycobacterium tuberculosis is the bacterium that as a single agent is known to cause the infection with the most morbidity and mortality around the world. It is known to cause pulmonary infection in immunocompetent patient, but its dissemination outside the lungs has been linked …
Chitra Rani, Raj Kishor Pandey, Shah Ubaid-ullah
Tuberculosis (TB) is an airborne communicable disease caused by a bacterial pathogen, Mycobacterium tuberculosis (M. tuberculosis), mainly affecting lungs. As per the World Health Organization (WHO), TB engulfs many lives every year globally. Due to its high mortality rate, TB is…
Zonghai Chen
Tuberculosis (TB) is an airborne infectious disease caused by the Mycobacterium tuberculosis (Mtb) complex, which is one of the top 10 causes of death in the world. In recent years, the rising incidence rate of drug-resistant TB has posed a challenge to traditional anti-TB drugs;…
Frank M. Collins
Mycobacterium tuberculosis is a highly infectious human pathogen which is spread person-to-person by means of droplet infection from a patient with open cavitary disease. Most adults are innately resistant to tuberculosis, developing a latent form of the disease in which small nu…
Rafael Laniado-Laborín
Despite recent advances in the pharmacologic treatment of tuberculosis, some patients are left with residual or persistent sequels that could benefit from surgical intervention. Most experts believe that surgical treatment is rarely necessary in patients with pansensitive tubercu…
Prita Patil, Vaibhav Narawade
…on of respiratory diseases such as COVID-19, pneumonia, and tuberculosis from chest X-ray images. The model aims to address the scarcity of competent radiologists by providing automated disease classification, aiding in timely and accurate diagnosis. We utilize a comprehensive da…
Lia D’Ambrosio, Denise Rossato Silva
With the overall goal of ending tuberculosis (TB), and eventually approaching TB elimination, several interventions need to be implemented. They include ‘in primis’ early and rapid diagnosis, and effective treatment of people with active disease and with latent TB infection. Glob…
Purvi M. Pandya, Ekta N. Jayswal, Yash Shah
…relationship between smoking and a perilous disease such as tuberculosis. This research work focuses on how drugs or medications can affect individuals who are susceptible to tuberculosis because of smoking habits and also on individuals who have already developed symptoms of tub…
Beaulah Jeyavathana Rajendran, K. V. Kanimozhi
Tuberculosis is one of the hazardous infectious diseases that can be categorized by the evolution of tubercles in the tissues. This disease mainly affects the lungs and also the other parts of the body. The disease can be easily diagnosed by the radiologists. The main objective o…
Mpho Phehello Ngoepe, Maluta Steven Mufamadi
… chemical methods. Treatment for extensively drug-resistant tuberculosis (TB) has always been a challenge, as many patients fail to complete treatment requiring four to five active drugs over a 24-month period. Failure to identify new antimicrobials is of major concern due to an …
Charles Oluwaseun Adetunji, Olugbenga Samuel Michael, Muhammad Akram, Oseni Kadiri, Ajayi Kolawole Temidayo, et al.
Mycobacterium tuberculosis (Mtb) is a non-motile, non-sporulating, strict aerobe, acid-fast rod that usually shows up unstained with Gram stain but, like all mycobacteria, appears stained with arylmethane dyes such as carbolfuchsin and rhodamine. The bacteria were assumed to be f…
Rafael Laniado-Laborı́n
…drug susceptibility testing. The presence of drug-resistant tuberculosis should be suspected in patients who are failing treatment, in patients with TB relapse, in subjects coming from regions with a high prevalence of MDR-TB, and in contacts of known cases of MDR-TB. Although th…
Charles Lukanga Kimera, Fredrick Sinyinza, Linda Ndesipandula Lukolo
…harge, abnormal vaginal bleeding or a lesion on the cervix, tuberculosis of the uterine cervix should be one the differential diagnoses. Being airborne, Tuberculosis (TB) commonly affects the lungs. However, TB can affect any organ of the body and when it is outside the lungs, it…
Globally in 2016, the total number of new cases of tuberculosis (TB) was estimated at 10.42 million, of which over 160 000 are observed in LAC. The number of TB deaths was estimated at 1.45 million, of which more than 15 000 occurred in LAC. Most of these TB cases and deaths occu…
Bali Thorat, Mukti E. Jadhav
Mycobacterium Tuberculosis is one of the most hazardous disease.Universally millions of people are suffering from this dangerous disease.Number of detection techniques are available, but due to its complex structure this infectious disease not get diagnose easily and within time.…