Showing 51–75 of 200 documents
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Anjali Dhote, Vikas Kawishwar
Tuberculosis is one of humanity's oldest diseases, as well as one of the deadliest epidemics. Mycobacterium tuberculosis infects one-third of the world's population, with 9.6 million new cases reported each year. Tuberculosis kills almost 1.45 million people per year, making it t…
Saurov Mahanta, Bhaskarjyoti Gogoi, Tanti Bhaben
Tuberculosis is the disease which is caused due to the infection of Mycobacterium tuberculosis. The multidrug resistance Mycobacterium tuberculosis is the main problem in the treatment of this worldwide health threats. So there is an urgent need for the development of new drug fo…
Dilvani Oliveira Santos, Paulo R. Z. Antas
Tuberculosis (TB) is a contagious infectious disease that is a major cause of morbidity, being one of the top 10 causes of death worldwide, and the leading one from a single infectious agent. Also called “White Plague” in the past, TB is an airborne disease, propagated when multi…
Simone Villa, Giovanni Battista Migliori, Lia D’Ambrosio, Mario Raviǵlione
Tuberculosis is an infectious disease caused by bacteria of the Mycobacterium tuberculosis complex that are transmitted through air droplets from persons with pulmonary tuberculosis. Once exposed, a person might become infected but only 5–10% of them will, eventually, develop the…
Xue‐Song Xiong, Qin Zhu, Zhan-Zhong Liu, Ting-Ting Huang, Jin-Bin Fan, et al.
…thogens in the genus Mycobacterium, including Mycobacterium tuberculosis (MTB) complex, nontuberculous mycobacteria (NTM), and Mycobacterium leprae. Tuberculosis caused by M. tuberculosis has become the leading cause of death of a single infectious disease after novel coronavirus…
Lucas Gabriel Quadros Ramos, Fernanda Moreira Soares Boaventura Silveira, Jessica Elen Martins Alves, Karina Andrade de Prince
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, considering that this comorbidity represents a public health problem, it is of paramount importance to understand the associated clinical, epidemiological, and economic factors due to its high prevalence …
W. Henry Boom
M. tuberculosis remains one of the most successful human pathogens. The ability of M. tuberculosis to elicit vigorous acquired immune responses and use of the macrophage as primary cell to infect, suggest that the organism has evolved multiple strategies to survive and persist in…
David N. McMurray
The relationship between malnutrition and tuberculosis is probably as ancient as the disease itself. One approach to the identification of nutritional determinants of resistance to tuberculosis has been to utilize a guinea pig model of low-dose pulmonary infection with virulent M…
Daniel Peptenatu, Aurel Mihail Băloi, Octavian Andronic, Andreea Karina Gruia, Alexandra Grecu, et al.
…singly recognized globally, and infectious diseases such as tuberculosis are significantly influenced by the quality of the environment. The research examines the correlation between contamination of the environment and the elevated prevalence of tuberculosis in Romania, one of t…
Evelina Lesnic, Alina Malic, Adriana Niguleanu, Tatiana Osipov
According to the actual national policy, the patients with tuberculosis may benefit from the following anti-tuberculosis treatment options: a) directly observed delivered in the community close to the patient’s home or work; b) treatment provided in hospitals or specialized dispe…
Sameh Mezri, Zitoun Chaima, Wadii Thabet, Chebbi Ghassen, K. Akkari
Background: Tuberculosis is a chronic specific infectious disease caused by mycobacteria: Koch bacillus (BK). Despite a re-increase in the incidence of tuberculosis, extra-nodal location on the head and neck remains rare. Clinical symptomatology is non-specific and even data from…
Abhishek Yadav, C.P. Baveja, Tanisha Bharara, Vasim Ahmad
Tuberculosis causes morbidity in millions of people per year and is one of the top 10 causes of mortality worldwide. Though pulmonary TB is the commonest form, extra–pulmonary Tuberculosis (EPTB) carries its fair share of morbidity and mortality. The various extra–pulmonary sites…
Rafael Laniado-Laborín
Traditionally little attention has been paid to pediatric tuberculosis by clinicians, researchers, decision-makers, and even by national tuberculosis programs. According to the World Health Organization (WHO) Global Report for the year 2018, 10 million people developed TB in 2017…
Christian W. McMillen
Abstract Tuberculosis, caused by Mycobacterium tuberculosis, emerged in Africa about seventy thousand years ago. It accompanied modern humans on their migrations out of Africa, across the Indian Ocean, and then into Eurasia. Tuberculosis affects almost all parts of the body. Its …
Gagan Chooramani, Pooja Singh
…e World Health Organization has declared that the spread of tuberculosis is a global emergency. Despite the implementation of strong tuberculosis-control initiatives by WHO, this highly infectious disease continues to affect all vulnerable populations, including the elderly popul…
Mani Sharma, Sakshi Kansal
Tuberculosis is the second most fatal infectious disease after AIDS. It is caused by the mycobacterium tuberculosis. There are numerous factors responsible for the emergence of multi-drug resistance and extensively drug resistance cases of tuberculosis, which involves high pill b…
Piyushkumar Sadhu, Mamta Kumari, Niyati Shah, Chitrali Talele, Nirmal Shah, et al.
Drug-resistant tuberculosis, particularly those with rifampicin resistance (RR-TB), has emerged as one of the major challenges to the goal of eliminating tuberculosis. Additionally, three or four different medications must be used in an effort to treat TB, but sadly, there aren't…
Awalagaway Dhulappa, Shuang Wang, Manik Prabhu Narsing Rao
The symptoms of tuberculosis vary depending on where the bacteria are developing in the body. In the case of pulmonary tuberculosis, symptoms may include a persistent cough, chest discomfort, hemoptysis, weakness or weariness, weight loss, fever, and night sweats. The risk of tub…
Dženan Kovačić, Adna Softić, Adna Salihović, Jovana Jotanović
Tuberculosis persists among the top 10 causes of death globally; causing 1.7 million deaths and 10 million new infections in 2018. Approximately 1/3 of the global population is infected with Mycobacterium tuberculosis; 10% of which are expected to develop active TB at some point …
Anil Kumar Gupta, Divakar Sharma, Amit Singh
Tuberculosis (TB) is a universally prevalent disease caused by an aerobic, gram-positive bacterium Mycobacterium tuberculosis (M. tuberculosis). It has continued to pose a significant threat to human health. The emergence of multi-drug resistance (MDR) strains of Mycobacterium tu…
Angelique Kany Kany Luabeya, Michèle Tameris, Justin Shenje, Anele Gela, Elisa Nemes, et al.
…ovis</italic> BCG and live-attenuated <italic>Mycobacterium tuberculosis</italic> candidates, are entering prevention of disease efficacy trials in infants and adolescents/adults. Several candidates are in nontraditional efficacy trials to prevent <italic>M. tuberculosis</italic>…
Sonali Paul, Nivedita Chatterjee, Asmeeta Sircar, Shimantika Maikap, Abhilasha Singh, et al.
Tuberculosis (TB) is primarily an airborne disease caused by the bacteria Mycobacterium tuberculosis. In a country such as India, the spread of this disease is quite rapid, especially with increasing air pollution. There are drugs for treatment, but these chemicals always have si…
Tirta Darmawan Susanto, Bambang Sutrisna, Asri C. Adisasmita, Annabella Vinsensa, Sapariah Anggraini
Background: Patients with chronic disease, including tuberculosis, can be easily get depressed. Valid and reliable instrument needed to detect depression in Tuberculosis patients. The Indonesian language version of Zung Self-Rating Depression Scale questionnaire is needed to be p…
Rosalind S. Abernathy
Tuberculosis was the major cause of death in Europe and North America in the 18th and 19th centuries. This chapter deals with pulmonary tuberculosis in children — its pathogenesis, clinical manifestations, diagnosis, management, and prognosis. The tuberculin test is the basic dia…
Kusum Sharma, Megha Sharma
Timely diagnosis of spinal tuberculosis is imperative to initiate appropriate therapy and to prevent long-term sequalae-like deformities. The clinical and radiological features have several mimickers, and microbiological evidence of Mycobacterium tuberculosis or its products form…