A Comprehensive Study of Multi-Drug Resistance in Tuberculosis

Tuberculosis is the second most fatal infectious disease after AIDS. It is caused by the mycobacterium tuberculosis. There are numerous factors responsible for the emergence of multi-drug resistance and extensively drug resistance cases of tuberculosis, which involves high pill burden, prolonged treatment, low compliance, and stiff administration schedules. Continuous efforts have been done to develop unique antibodies and nanocarrier-based drug delivery systems that can overcome drug resistance, reduce the treatment regimen, and elevate the compliance to treatment. Therefore, there is a need for a robust system to subdue these technological drawbacks in the urge to develop therapeutically active system in terms of pharmaceutical technology. It is difficult to treat prolonged multi-drug-resistant tuberculosis giving higher side effects and expenses and more unsuccessful results. In short, the authors tried to uncover all the urgent needs in the treatment and prevention of multi-drug-resistant tuberculosis through adequate strategies.