Showing 126–150 of 200 documents
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Mariana Baptista Angeluci, Marilda Aparecida Milanêz Morgado de Abreu, Ana Cláudia Cavalcante Espósito, Eduardo Vinícius Mendes Roncada, Cristhiana Kise Saito, et al.
…ts and, consequently, increases the risk of reactivation of latent infections, such as tuberculosis (TB). 2 Recent guidelines recommend carrying out TB screening before starting treatment with any immunobiological agent, using the tuberculin skin test (TST) or interferon gama rel…
Dibash Kumar Das
…checkpoint inhibitors (ICIs) have been revolutionary in the treatment of various cancer types, demonstrating favorable outcomes and having been generally well-tolerated by patients with cancer compared to cytotoxic therapy (Front Oncol 2021; doi: 10.3389/fonc.2021.625872). ICIs e…
Jorge Cardenas, Maria E. Campos-Bonaguro, Jacques Simkins
…than 80% of active TB cases arise from previously untreated latent tuberculosis infection (LTBI),3 hence preventive strategies are paramount. In light of the significant burden that TB may inflict in this population, routine screening for LTBI in liver transplant candidates (LTCs…
Siva Prasad Korikana, Sreenivasa Rao Battula, Naresh Konduru, Aravind Kurnool, Divya Kumar Vemuri, et al.
…pentine, an essential therapeutic agent for both active and latent tuberculosis (TB). The chromatographic separation was achieved on a YMC Pack C18 column (250 × 4.6 mm, 5 μm) using a gradient elution with Solvent A composed of phosphate buf…
Vadakkan Devassy T, K V S, Jacob A, Meleppat VM
…icating clinical status of paediatric oncology patients and treatment of infection with this bacilli is challenging in this subpopulation of patients because of ongoing immunosuppression and relative lack of published guidelines. Atypical presentations of tuberculosis in children…
Xi Wang, Shengfei Hu, Rui Hong, Xi Cheng, Ye Hong, et al.
…ptica spectrum disorder (NMOSD). Currently, no standardized guidelines exist for preventing hepatitis B reactivation (HBVr) or tuberculosis reactivation (TBr) during the use of B cell-depleting agents in patients with NMOSD who are at risk of HBVr or TBr. Furthermore, data on HBV…
Mariano Victor, Andrade Laíla, Oliveira Fernanda, Santos Monique, Pereira Martins Fernanda, et al.
…e, potent immunosuppressive therapy has become the standard treatment for inflammatory bowel disease (IBD) (1). However, the increasingly use of immunomodulators associated to biological therapy—especially the inhibitors of tumor necrosis factor alpha (TNF-α)—have considerably in…
Gèrard de Vries, Jossy van den Boogaard, Ibrahim Abubakar
…ation was unchanged in the 2021 update [[3]WHO consolidated guidelines on tuberculosisModule 2: screening - systematic screening for tuberculosis disease. World Health Organization, Geneva2021Google Scholar]. The specific details of the combination of tools to use in such screeni…
Sashi N Nair, Indira Brar, Gireeshkumar K.P.
…cribed in HIV infected patients. Developed countries, where guidelines on the treatment of PJP have been created have dramatically lower rates of latent and active TB than developing countries. PJP may obscure the diagnosis or delay the treatment of TB. Furthermore, treatment of …
Nair S, Brar I, K.P. G
…cribed in HIV infected patients. Developed countries, where guidelines on the treatment of PJP have been created have dramatically lower rates of latent and active TB than developing countries. PJP may obscure the diagnosis or delay the treatment of TB. Furthermore, treatment of …
Cheon J, Kim C, Park EJ, Ock M, Lee H, et al.
…culosis (TB) develops in approximately 10% of people with a latent tuberculosis infection (LTBI). TB guidelines recommend that LTBI screening and treatments target high-risk patients. Malignancies are not universally considered a high-risk factor for active TB. This study aimed t…
Sarah van de Berg, Andreas Beyerlein, Johannes Stephani, Beatrix Bäumler-Merl, Manuela Jäger, et al.
…ield of TB contact investigations, compliance with national guidelines and risk factors for infection among contacts.METHODSWe analysed anonymised data of TB patients and their contacts collected between 2018 and 2022 in Upper Bavaria, Germany. We assessed testing coverage, laten…
Joyce W.Y. Mak, Joseph J.�Y. Sung
… of concerns for the use of these drugs in the East. First, latent infection is a major threat when using potent immunosuppressive agents. The high prevalence of subclinical or past infection of tuberculosis, viral hepatitis, and other latent infections poses potential danger of …
Judi Chen, Weining Cao, Renfang Chen, Yong Ren, Tao Li
…an immunodeficiency virus (HIV) worldwide are infected with latent tuberculosis (TB). The aim of this study was to determine the rate of HIV infection in TB patients and its determinants in Wuxi City, China. TB patients attending health institutions (12 selected sites) for TB dia…
Chitnis AS, Cheung R, Gish RG, Wong RJ
…nic hepatitis B virus (CHB) infection can be prevented with treatment and vaccination, respectively. We reviewed epidemiology and guidelines for TB and CHB to inform strategies for reducing United States (U.S.) burden of both infections. Non-U.S.-born, compared to U.S.-born, pers…
Ronald LA, Campbell JR, Balshaw RF, Romanowski K, Roth DZ, et al.
Background Canadian tuberculosis (TB) guidelines recommend targeting postlanding screening for and treatment of latent tuberculosis infection (LTBI) in people migrating to Canada who are at increased risk for TB reactivation. Our objectives were to calculate robust longitudinal e…
Ghassan Ilaiwy, Jessica Keim‐Malpass, Romella Tuppal, Alexander F. Ritua, Flordeliza R. Bassiag, et al.
…d a cost effectiveness analysis evaluating the expansion of latent TB testing and treatment among pediatric (5-14 years) household contacts of index TB patients in the Philippines. Methods : Using a Markov state transition model, eligible household contacts (HHCs) age 5-14 years …
S Pappas, Y Zhu, S Hegeman, D S Mohamed, N Kalra, et al.
…sts between Omalizumab and pulmonary disease, nor are there guidelines recommending TB screening before therapy [6]. A single report described a 32-year-old Filipino woman diagnosed with pulmonary and extrapulmonary TB after starting Omalizumab for CSU [7]. Mast cells play a para…
Grasa Lozano CD, Baro-Fernández M, Rubio-San-Simón A, Blázquez-Gamero D, López-Roa P, et al.
Background There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected. Methods After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time …
Arafa Djalal, Justin Côté-Daigneault
Inflammatory bowel disease (IBD) patients undergoing treatment with biological therapy are at increased risk of developing opportunistic infections such as tuberculosis (TB). Screening for latent tuberculosis is mandatory before initiating biological therapy such as Anti-TNF alph…
R. De Luca E Tuma, Amina Jama, Susan Dart, Verónica White, Christabelle Chen, et al.
…of MDR-TB in East London remain high. There are no existing guidelines for treating close contacts of newly diagnosed MDR-TB cases in low TB incidence countries. This study aims to analyze the rates of MDR-TB among close contacts of TB index cases with pulmonary MDR-TB in East Lo…
Maria Mironova, Irina Y. Gutierrez Puentes, Rajashree Anandakrishnan, Anil R. Balani
…or necrosis factor alpha (anti-TNF) medication used for the treatment of moderate-to-severe Crohn’s disease and ulcerative colitis. Tuberculosis (TB) has remained a serious side effect of anti-TNF therapy despite routine TB screening. We report a case of a young male who develope…
Pop R, Kaelin MB, Kuster SP, Sax H, Rampini SK, et al.
…d exposure to sputum smear positive tuberculosis (TB). NICE guidelines give support regarding investigation and treatment intervention, but not for contact definitions. Data regarding the reliability of any interferon gamma release assay (IGRA) in infants as a screening test for …
Farah Daas, Rafael Ruiz‐Gaviria, Bhakti Thummar, Naveera Khan, Sheena Ramdeen
…y (IGRA) is frequently ordered in hospitalized patients for latent tuberculosis (TB) screening. Health care workers must be cautioned that acute and critical illness exert a significant effect on IGRA performance, so delaying screening to the outpatient setting is preferred if fe…
Djalal A, Côté-Daigneault J
…ground Inflammatory bowel disease (IBD) patients undergoing treatment with biological therapy are at increased risk of developing opportunistic infections such as tuberculosis (TB). Screening for latent tuberculosis is mandatory before initiating biological therapy such as Anti-T…