Showing 101–125 of 200 documents
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Ford N, Maher D, Rangaka MX, Baddeley A, Singh S, et al.
Purpose of review Guidelines developed by the WHO aim to provide recommendations to support best practice in health delivery, with a focus on low-income and middle-income countries. As part of the guideline development process, critical knowledge gaps are identified and one of th…
Swain S, Kumar A, Vishwakarma VK, Aayilliath K A, Mittal A, et al.
…and around 18-36 lakh develop active tuberculosis annually. Latent TB is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifested active TB. The progression of a latent infection to active tub…
Yu Chen, Yaguo Wang, Joy Fleming, Yanhong Yu, Ye Gu, et al.
…with M. tuberculosis (MTB), the pathogen that causes TB and latently infects ∼25% of the global population, may be a risk factor for SARS-CoV-2 infection and severe COVID-19 pneumonia. Objective To determine if latent or active TB increase susceptibility to SARS-COV-19 infection …
Alzahabi KH, Usmani O, Georgiou TK, Ryan MP, Robertson BD, et al.
…sulting with a mortality approximating 1.5 million. Current treatment guidelines recommend oral administration of a combination of first-line anti-TB drugs for at least 6 months. While efficacious under optimum conditions, 'Directly Observed Therapy Short-course' (DOTS) is not wi…
Faust L, Ruhwald M, Schumacher S, Pai M
… aims Despite the World Health Organization (WHO)'s updated guidelines on tuberculosis (TB) preventive treatment, the scale-up of TB preventive therapy remains low in many high-burden countries (HBCs). We conducted a survey to better understand the current status of policy implem…
Hargreaves S, Nellums LB, Johnson C, Goldberg J, Pantelidis P, et al.
Background Screening for latent tuberculosis infection (LTBI) in migrants is important for elimination of tuberculosis in low-incidence countries, alongside the need to detect blood-borne infections to align with new guidelines on migrant screening for multiple infections in Euro…
Phani V Akella, Rachel Sigler
…ent AMR and Grade 1R acute cellular rejection (ACR) needing treatment with plasmapheresis, intravenous immunoglobulin (IVIG) and steroids. About three weeks post OHT, she developed fever, lactic acidosis, and hypotension. Infectious workup including blood cultures, respiratory pa…
Migliori GB, Tiberi S, Tiberi S, Zumla A, Petersen E, et al.
…ntinuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from con…
Wyndham-Thomas C, Dirix V, Goffard JC, Henrard S, Wanlin M, et al.
…jectives : To review the current knowledge on screening for latent tuberculosis infection (LTBI) in HIV-infected adults and provide specific guidelines for Belgium. Focus is given to who to test, which testing method to use, timing of screening and choice of LTBI treatment. Metho…
Brett K, Severn M
…ency in the majority (i.e., around 95%) of people, known as latent TB infection. People with latent TB do not have any symptoms, and cannot spread the TB infection to others, however, they can develop active TB disease., Active TB disease occurs when the TB bacteria overwhelm the…
Starke SJ, Martinez Rivera MB, Krishnan S, Shah M
…take on an expanded role in the diagnosis and management of latent tuberculosis infection (LTBI). Clinical practice guidelines and recommendations exist for LTBI management, but there is a need for innovative tools to improve medical students' and residents' knowledge of evidence…
Kendra Brett, Melissa Severn
…ency in the majority (i.e., around 95%) of people, known as latent TB infection. People with latent TB do not have any symptoms, and cannot spread the TB infection to others, however, they can develop active TB disease., Active TB disease occurs when the TB bacteria overwhelm the…
Lana Fadl, Arowa Abdelgadir, Hendy Mirza, Aqsa Mahreen, Siddalingana Gouda
…cept, golimumab, and infliximab—are recommended for severe, treatment-resistant AS. Adalimumab, a monoclonal anti-TNF-α antibody, has been linked to a higher tuberculosis (TB) risk than etanercept, with literature suggesting a three- to fourfold increase. We present a rare case o…
Occhineri S, Matucci T, Rindi L, Tiseo G, Falcone M, et al.
…d Health Organization (WHO) determined to include PA in its guidelines for the treatment of rifampicin-resistant (RR), multi drug resistant (MDR) and pre-extensively drug resistant TB (pre-XDR-TB) with BDQ, LZD and Moxifloxacine (MFX) in a 6-month regimen. Although further studie…
Gröschel MI, van den Boom M, Migliori GB, Dara M
… the existing World Health Organization (WHO) documents and guidelines on childhood and adolescent TB and describe the outcomes of this regional meeting. National childhood and adolescent TB guidelines are available in 25% of Member States, while 33% reported that no such guideli…
Yu Bai, Y. Xue, Mucong Li, Mengtao Li, Chanyuan Wu
…rom approximately 1.2 to over 5, depending on disease type, treatment exposure, and regional TB burden.[3,4] Beyond absolute prevalence, longitudinal data further highlight the sustained and cumulative risk of TB over time in RMD cohorts. Population-based studies from Sweden have…
Friedman A, DeGeorge KC
… demonstrated minimal clinical improvement after initiating treatment for COVID-19, further investigations uncovered concomitant reactivated TB. This case is helpful in underscoring the potential implications of the COVID-19 pandemic and current treatment guidelines on the global…
Gisele Meinerz, Cynthia Keitel da Silva, Damaris Mikaela Balin Dorsdt, Julia Bertoni Adames, Julio Pasquali Andrade, et al.
… infectious complication after kidney transplantation (KT). Latent tuberculosis infection (LTI) screening and treatment is fundamental to prevent post-transplant active disease. Methods: We described a cohort of adult KT recipients from April 4th, 2014 to October 31st, 2018, with…
Fröberg G, Jansson L, Nyberg K, Obasi B, Westling K, et al.
Swedish National tuberculosis (TB) guidelines recommend screening of active and latent TB (LTBI) among pregnant women (PW) from high-endemic countries or with previous exposure to possibly improve early detection and treatment.We evaluated cascade of care of a newly introduced TB…
Cheng Chen, Leonardo Martínez, Biao Xu
…d predict the risk of progress to TB disease in people with latent tuberculosis infection (LTBI). Recently, human genetic, immunological and metabolic biomarkers have been considered having promising prospects in monitoring and predicting TB risks qualitatively and quantitatively…
Fine S, Vecchio M, Filipe Goncalves Monteiro J, Vecchio E, Mao EJ
Background Biologic treatment for moderate to severe inflammatory bowel disease (IBD) places patients at risk for infectious complications. Tuberculosis (TB) infection and reactivation can lead to serious morbidity and mortality for immunosuppressed patients. As a result, guideli…
Phool Iqbal, Ashraf Tawfiq Soliman, Vincenzo Desanctis, Mohamed A. Yassin
…e. Tyrosine kinase inhibitors (TKI) are the mainstay of the treatment to achieve remission, while bone marrow transplant is the only proven cure. Tuberculosis (TB), both active and reactivation of latent TB, remains the most common infectious disease worldwide and leads to high m…
Jyoti S. Mathad, Sylvia M. LaCourse, Amita Gupta
…ganization (WHO) recommends improving access to testing and treatment of latent TB infection (LTBI) [1]. Despite recent epidemiologic studies demonstrating an approximately twofold increased risk of active TB in peripartum women [2], and poor outcomes associated with TB during pr…
Bhumika Harishkumar Bhavsar, Vipul D. Prajapati, Dhaiwat Shukla, Supriya Malhotra
… for autoimmune diseases, raises concern about reactivating latent tuberculosis (TB) and new-onset TB. Despite its established efficacy in managing inflammation, clinicians must recognize and manage adalimumab-induced TB promptly to minimize associated morbidity. This case report…
Nisha Yadav, Sushant Satish Mane, Jyothi Janardhanan, Manas Pustake, Gazi Israil Khan, et al.
of hospital stay in COVID-19 patients with TB, and treatment of COVID-19 in TB. Materials a n d Methods Study DesignA retrospective observational study was done at a tertiary care hospital in Mumbai, India.Children with TB and those without TB were enrolled in the study.According…