Showing 101–125 of 200 documents
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Adepoju VA, Onyezue OI
…ases and 1.4 million deaths in 2020 alone, new and improved vaccines are urgently needed. Recent advancements in TB vaccine research offer hope, but a lack of funding, coordination and understanding of immune responses have impeded progress. A TB Vaccine Accelerator Council aims …
Anurag Bhargava
Nutrition is essential to survival, health, and protection from disease across the lifespan. In the 1970s, an adequate diet was described as the most effective vaccine available for respiratory, diarrheal, and other common infections, as nutritional supplementation reduced these …
Dockrell HM, Butkeviciute E
The BCG vaccine will, in 2021, have been in use for 100 years. Much remains to be understood, including the reasons for its variable efficacy against pulmonary tuberculosis in adults. This review will discuss what has been learnt about the BCG vaccine in the last two decades, and…
Schaltz-Buchholzer F, Kjær Sørensen M, Benn CS, Aaby P
Background Following the introduction of oral Bacille Calmette-Guérin (BCG) a century ago, Albert Calmette suggested that BCG both provided protection against death from tuberculosis (TB) and other causes. The findings were not pursued. Today, there is considerable evidence that …
Wong NX, Buttery J, McMinn A, Azhar Z, Crawford NW
Bacille Calmete-Guerin vaccine is widely administered to reduce the risk of severe tuberculosis disease in children. Recent global vaccine supply issues have led to the use of alternative products, which may vary in side effect profile. We report on the safety of the Polish (More…
Liebler-Tenorio EM, Heyl J, Wedlich N, Figl J, Köhler H, et al.
…models to compare reactions to different mycobacteria or TB vaccines.
Stewart EL, Counoupas C, Quan DH, Wang T, Petrovsky N, et al.
…able protection; however, the development of more effective vaccines is hindered by a lack of defined correlates of protection (CoP) against M. tuberculosis . Pulmonary vaccine delivery is a promising strategy since it may promote lung-resident immune memory that can respond rapi…
Justiz Vaillant AA, Grella MJ
…unities alike. The gamut of diseases currently addressed by vaccines is extensive, encompassing diphtheria, tetanus, pertussis, poliomyelitis, measles, mumps, rubella, pneumococcal pneumonia, smallpox, sepsis, meningitis, hepatitis B, varicella-zoster, tuberculosis, cholera, rota…
Rappuoli R, Black S, Bloom DE
Most vaccines for diseases in low- and middle-income countries fail to be developed because of weak or absent market incentives. Conquering diseases such as tuberculosis, HIV, malaria, and Ebola, as well as illnesses caused by multidrug-resistant pathogens, requires considerable …
Kwon BE, Ahn JH, Park EK, Jeong H, Lee HJ, et al.
Early secretory antigenic target-6 (ESAT6) is a potent immunogenic antigen expressed in Mycobacterium tuberculosis as well as in some non-tuberculous mycobacteria (NTM), such as M. kansasii . M. kansasii is one of the most clinically relevant species of NTM that causes mycobacter…
Roces CB, Hussain MT, Schmidt ST, Christensen D, Perrie Y
…(lungs) have been considered for the development of subunit vaccines. Inert delivery systems such as poly (lactic-co-glycolic acid) (PLGA) are an interesting approach due to its approval for human use. However, PLGA suffers hydrolytic degradation when stored in a liquid environme…
ФГБОУ ВО «Астраханский государственный медицинский университет» Минздрава России, Л. Г. Тарасова, E.N. Streltzova
BCG is a unique vaccine. It was created and successfully used for specific prevention of tuberculosis. Reactivation of the BCG scar is a transient condition that occurs against the background of various diseases, capable of resolving itself, does not involve surgical intervention…
Yang Wang, Fei Ge, Junhai Wang, Hanglin Li, Boyang Zheng, et al.
…bstacle to the development of safe and effective killed RSV vaccines.
Daifulah Al-Zahrani
Tuberculosis (TB) is considered by WHO as a worldwide wellbeing crisis in 1993. In 2011 33% of the total populace was believed to be contaminated with TB and 8.7 million instances of dynamic TB every year. BCG antibody is one of the successful control measures to forestall TB. It…
Gönül Aslan, Deniz Alkaya
ÖzTüberküloz (TB) Mycobacterium tuberculosis kompleksi'nin etken olduğu ciddi etkileri nedeniyle insanlık tarihi boyunca toplumları derinden etkileyen bulaşıcı bir hastalıktır.TB'den korunmada tarihi bir öneme sahip olan Bacille Calmette-Guérin (BCG) aşısı 100 yıllık geçmişi ile
Goudouris E, Aranda CS, Solé D
Objectives Since the beginning of its use for the prevention of tuberculosis (TB) in 1921, other uses of BCG (Bacillus Calmette-Guérin) have been proposed, particularly in the treatment of malignant solid tumors, multiple sclerosis, and other autoimmune diseases. Its beneficial i…
Darmanger, A. M., Nekzad, S. M., Kuis, M., ten Dam, H. G.
World Health Organization = Organisation mondiale de la Santé
Wang J, Xie T, Ullah I, Mi Y, Li X, et al.
Concerns were brought to the attention of the journal's editorial office after the paper was published [...].
A. М. Krychkovska, N. L. Zayarnyuk, О. І. Lopatynska, L. D. Bolibruh, В. П. Новіков
International scientific and practical conference «New trends and unresolved issues of preventive and clinical medicine» : Conference proceedings, September 25–26, 2020. Lublin : Izdevnieciba «Baltija Publishing», 2020. 428 pages.
World Health Organization
World Health Organization
Mussi-Pinhata, M. M., Goncalves, A. L., Foss, N. T.
World Health Organization
World Health Organization