Showing 76–100 of 200 documents
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A R Dashuki, Aimi Nadira Mat Ruzlin, Mohd ‘Ammar Ihsan Ahmad Zamzuri, X W Chen
INTRODUCTION: Tuberculosis (TB) is one of the major global health challenges and concerns. Despite the availability of effective treatment in Malaysia, it remained a consistently high notification rate of TB cases. The objective of this study was to determine the proportion of su…
Kapata N, Tembo J, Mwaba P, Nabyonga-Orem J, Ntoumi F, et al.
Tuberculosis (TB) remains a leading cause of morbidity and mortality in Africa, with latent TB infection (LTBI) and TB co-infections posing significant public health challenges. This viewpoint examines the undiagnosed burden of LTBI and TB co-infections across the continent, emph…
Sharma R, Prajapati S, Patel P, Patel B, Gajjar S, et al.
…spite the nationwide implementation of the Revised National Tuberculosis Control Program in India, adverse outcome after treatment is on rise. Program guidelines propose follow-up of cured patients for 2 years which is rarely done. Objectives The main objectives of this study is …
Malwe S, Bawiskar D, Wagh V
The revised National Tuberculosis (TB) Control Program is an initiative undertaken by the government of India and was active from 1997 to 2020. Later it was renamed as National TB Elimination Program, which eyes the complete eradication of TB by 2025. The revised National Tubercu…
Gong W, Wu X
As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the largest source of new TB cases and is one of the biggest obstacles to achieving the aim of the E…
Kamolratanakul S, Ariyanon W, Udompornpitak K, Bhunyakarnjanarat T, Leelahavanichkul A, et al.
…r how the immune system controls the transition from latent tuberculosis (TB) infection (LTBI) to active pulmonary infection (PTB). Here, we applied mass spectrometry cytometry time-of-flight (CyTOF) analysis of peripheral blood mononuclear cells to compare the immunological land…
Rim Abbas, Ali Salami, Ghassan Ghssein
Tuberculosis (TB) is an infectious disease caused by bacteria that primarily target the lungs. The transmission of this disease occurs through the air in the form of droplet nuclei. Unfortunately, there has been an emergence of resistance to strains of such infections, such as mu…
Thibaut Morel-Journel, Christophe Guyeux, Christophe Sola
Lineage 1 is an ancestral lineage of the Mycobacterium tuberculosis complex (MTBC) comprising five sublineages. In a previous study, we suggested that a representative of sublineage L1.1.3, present in both Mozambique and northern Brazil, SIT129, may have been brought to Brazil by…
Sinshaw W, Kebede A, Bitew A, Tesfaye E, Tadesse M, et al.
…ted risk factors among presumptive smear negative pulmonary tuberculosis patients in Addis Ababa, Ethiopia. Methods Analytic cross sectional study design was used. A total of 418 smear negative presumptive pulmonary TB patients were enrolled from selected health facilities since …
Chang CJ, Huang JR, Tseng YH, Pan SW, Feng JY, et al.
… of circulating cell-free DNA (cfDNA) differentiates active tuberculosis (TB) from latent TB infection (LTBI). Methods Patients with pulmonary TB, contacts with LTBI, and healthy controls were enrolled (2018-2021). Plasma cfDNA was extracted, and using a 5-methylcytosine (5mC) DN…
Erkihun M, Kiros T, Berhan A, Ayele B
Introduction. Multi-drug-resistant tuberculosis (MDR-TB) is an emerging global challenge. Ethiopia is one of the 20 top countries with the highest estimated numbers of incidents of MDR-TB. Recently, the World Health Organization warned that drug-resistant TB is escalating and cal…
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, et al.
…s growing on the overall impact of the COVID-19 pandemic on tuberculosis (TB) services, global studies based on national data are needed to better quantify the extent of the impact and the countries' preparedness to tackle the two diseases. The aim of this study was to compare th…
Sharma N, Bakshi R, Basu S, Zode M, Arora R, et al.
…nitiation, implementation and treatment completion rates of tuberculosis (TB) preventive therapy (TPT) using 3HP (INH-Rifapentine) among household contacts of microbiologically confirmed drug sensitive TB cases on anti-tubercular treatment under programmatic real-world settings. …
Woodruff R, Pratt R, Kolasa M
Problem/condition Elimination of tuberculosis (TB) is defined as reducing TB disease incidence in the United States to less than 1 case per million persons per year. In 2022, TB incidence in the United States was 2.5 TB cases per 100,000 persons. CDC's TB program developed a set …
Ricvan Dana Nindrea, Milya Novera, Armaita, Long Chiau Ming, Lemmuel Tayo, et al.
Tuberculosis (TB) treatment adherence remained a major challenge in high-burden settings, and psychosocial factors such as TB-related stigma and patient motivation may be associated with whether patients completed therapy. This study examined the relationships between TB-related …
Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, et al.
… are increasingly used in children to establish evidence of tuberculosis (TB) infection and to assist in the diagnosis of TB disease. The QuantiFERON-TB Gold In-Tube assay is being phased out in favor of a next-generation test, the QuantiFERON-TB Gold Plus (QFT-Plus) assay. The Q…
Yusup Subagio Sutanto, Magdalena Sutanto, Agnes Sri Harti, Nony Puspawati
… this research is to study the sensitivity of Mycobacterium tuberculosis (MTB) isolates from suspect TB patients to seromucous of snail and chitosan as an alternative to anti-TB drugs.
 Methods: The research methods include management specimen, freeze-drying of snail seromuc…
T. Anupama, Megha Priyadarshini, Swaraj Sinha, Smiti Narain, Pritam Ghosh, et al.
Background: To increase community participation in tuberculosis (TB) elimination efforts, the government of India has launched ‘Pradhan Mantri TB Mukt Bharath Abhiyan’ (PMTBMBA) under the national TB elimination programme. The scheme allows interested parties (Ni-kshay mitras) to…
Dickens Odongo
Tuberculosis from a TB hotspots map (Appendix 1) in 3 parishes of Kitwe Central, Rukoni, and Kafunjo between December 2020 to September 2021. Areas with more than 31.8 cases of TB as per the hotspot map guided the team on where to put outreach posts. The team mobilized those with…
Linda B.K.
Tuberculosis (TB), despite availability of preventive and curative measures, remains a public health challenge, ranked among leading contributors of mortality globally, even with enactment of global and national control statergies.
Yun‐Jeong Jeong, Jae Seuk Park, Hyung Woo Kim, Jinsoo Min, Yousang Ko, et al.
<b>Background:</b> Tuberculosis (TB) remains an unresolved public health problem and is the leading cause of death attributable to a single infectious pathogen. The first step in developing strategies to reduce TB mortality is to identify the direct causes of death in patients wi…
Nababan B, Triasih R, Chan G, Dwihardiani B, Hidayat A, et al.
In Indonesia, the implementation of tuberculosis (TB) contact investigation is limited, with low detection rates. We report the yield of and risk factors for TB disease and infection for household contacts (HHCs) investigated using chest X-ray (CXR) screening. We identified HHCs …
Utpat KV, Rajpurohit R, Desai U
Background Drug-resistant tuberculosis (DR-TB) is the most exigent and calamitous challenge encountered in treatment of TB. Extra pulmonary (EP) DR-TB poses a complex diagnostic and therapeutic challenge owing to myriad of presentations and paucibacillary nature. Data available o…
Massi MN, Hidayah N, Handayani I, Iskandar IW, Djannah F, et al.
…ificance as an immunomarker for several diseases, including tuberculosis. This study aimed to determine the difference between miR-425-5p and miR-4523 expressions in patients with active pulmonary TB (PTB), latent TB infection (LTBI), and lymph node TB (LNTB), whose diagnosis rem…
Alemu A, Diriba G, Seid G, Wondimu A, Moga S, et al.
Objectives To assess tuberculosis (TB) and associated factors among patients with presumptive TB with chronic kidney disease (CKD). Methods A prospective cross-sectional study was conducted from January to December 2023 among 381 patients with CKD attending six hospitals found in…