Showing 51–75 of 200 documents
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Vidya Mave, Samyra R. Cox, Akshay Gupte, Jonathan E. Golub
…tuberculosis (TB) and 662,000 (6%) of them were living with HIV. Over the same period, an estimated 1.1 million people died with TB, and HIV co-infection contributed to an additional 161,000 TB-related deaths [1]. Since 2010, global TB incidence and related mortality have been gr…
Guo Q, Zhong Y, Wang Z, Cao T, Zhang M, et al.
…mmune dysregulation in human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) co-infection; however, the characteristics and role of these subclusters are unknown. Peripheral blood mononuclear cells (PBMCs) of patients with HIV-1 infection alone (HIV-pre) and those wit…
Ndakidemi E, Emerson C, Medley A, Ngowi B, Ng'eno B, et al.
…GROUND: Tuberculosis (TB) and human immunodeficiency virus (HIV) infection in children are of concern due to the high morbidity and mortality they engender. Tanzania is working to improve TB and HIV case identification and treatment, as well as linkage of TB and HIV care in pedia…
Otiende V, Achia T, Mwambi H
…kground Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) diseases are globally acknowledged as a public health challenge that exhibits adverse bidirectional relations due to the co-epidemic overlap. To understand the co-infection burden we used the case notification data …
Naidoo K, Gengiah S, Yende-Zuma N, Mlobeli R, Ngozo J, et al.
Background HIV-TB treatment integration reduces mortality. Operational implementation of integrated services is challenging. This study assessed the impact of quality improvement (QI) for HIV-TB integration on mortality within primary healthcare (PHC) clinics in South Africa. Met…
Solange Mudih Ngala, Disline Manli Tantoh, Oswald Ndi Nfor, Gamo Djouomo Francis, Adeline Fitame, et al.
…culosis (M. tuberculosis) and Human Immunodeficiency Virus (HIV) poses significant global public health challenges, with varying impacts across age cohorts. Evaluating tuberculosis (TB) treatment outcomes, especially among HIV patients across different age groups, is crucial for …
R. K. Mishra, Amar Prakash Garg, Tungvir Singh Arya
…roduction: The co-infection of Human Immunodeciency Virus (HIV) and Tuberculosis (TB) presents a signicant public health challenge in India. This paper investigates the quality of life (QOL) and psychosocial factors affecting individuals with HIV alone and those with HIV-TB co-…
Akansha Soni, Vimala Venkatesh, Parul Jain, Amita Jain, D Himanshu Reddy, et al.
Human immunodeficiency virus (HIV) is the major cause of failure to reach targets of tuberculosis (TB) control in settings with high HIV loads. TB, on the other hand, enhances the progression of HIV infection to AIDS. This study was done to understand the epidemiological and clin…
Indana Eva Ajmala, Laksmi Wulandari
TB and HIV have a very close relationship since the development of AIDS. Through a significant reduction in cellular immunity, HIV affects the pathogenesis of tuberculosis, thereby increasing the risk of TB in HIV co-infected individuals. In 2006, there were an estimated 9.2 mill…
O. V. Chizhova, Evgeny Belilovskiy, Borisov Se, M. V. Sinitsyn
…e incidence of TB death cases in the presence or absence of HIV infection is different. <b>Aims:</b> Assessment of the presence of seasonal differences in mortality depending on the presence of HIV infection <b>Methods:</b> TB associated monthly deaths of TB/HIV+ (926) and TB/HIV…
Manuel Barron, Stefano Bertozzi, Paul Gertler
… treat its funding is disproportionately lower than that of HIV. This study aims to assess the economic costs of TB versus HIV and evaluate the returns on investment in TB prevention compared to HIV. **METHODS:** The study uses a microfoundations behavioural model to estimate th…
Khan NH, Kohli M, Gupta K, Das BK, Pandey RM, et al.
…ntroduction The present study aimed to report the prevalent HIV-1 drug-resistant mutations in patients with HIV-1 alone and tuberculosis (TB) coinfection alone to improve our understanding of the mutation patterns and aid treatment decisions. Methods Patients with HIV-1 and HIV-T…
Nardotto GHB, Bollela VR, Rocha A, Della Pasqua O, Lanchote VL
There are contrasting findings regarding the effect of HIV on the pharmacokinetics of first-line anti-tubercular drugs (FLATDs) due to a lack of prospective controlled clinical studies, including patients with tuberculosis (TB) and patients with TB living with HIV. This study aim…
Friis H, Frahm Olsen M, Filteau S
… major infectious diseases in adults: tuberculosis (TB) and HIV infection. Despite obvious differences between HIV and TB, both are characterized by wasting and often affect underprivileged individuals. Furthermore, HIV is a strong determinant of TB, so co-infections are common. …
Buck WC, Nguyen H, Siapka M, Basu L, Greenberg Cowan J, et al.
… Pediatric tuberculosis (TB), human immunodeficiency virus (HIV), and TB-HIV co-infection are health problems with evidence-based diagnostic and treatment algorithms that can reduce morbidity and mortality. Implementation and operational barriers affect adherence to guidelines in…
Alex R. Ario, Lilian Bulage, Yvette Wibabara, Peter Muwereza, Daniel Eurien, et al.
Despite remarkable progress in controlling HIV and TB, Uganda is one of the 30 high-burden TB/HIV countries. Approximately 53,000 Ugandans had a new HIV diagnosis in 2019, and approximately 88,000 Ugandans had a TB diagnosis in 2020. Fellows in the Uganda Public Health Fellowship…
Winter JR, Stagg HR, Smith CJ, Lalor MK, Davidson JA, et al.
Background HIV increases the progression of latent tuberculosis (TB) infection to active disease and contributed to increased TB in the UK until 2004. We describe temporal trends in HIV infection amongst patients with TB and identify factors associated with HIV infection. Methods…
Hitender Gautam, Bhanu Mehra, Monika Matlani, Deepti Rawat, Preena Bhalla
BACKGROUND: Human immunodeficiency virus (HIV) and tuberculosis (TB) epidemics continue to fuel each other and with dual infections with these two deadly diseases on the rise, it becomes imperative to devise effective HIV-TB collaborative strategies. The present study was designe…
López-Medina EM, Sainz T, de Ory SJ, Mellado-Peña MJ, González-Tomé MI, et al.
…ic infection in children with human immunodeficiency virus (HIV), but is uncommon in low prevalence regions. We aim to describe the changing epidemiology and clinical presentation of TB-HIV co-infection in a cohort of HIV-infected children in Spain. METHODS: Children diagnosed wi…
Titi Supriati, Yodi Mahendradhata, Ari Probandari
…ed services, including diagnostic screening and care for TB-HIV patients. Kulon Progo seeks to improve services under existing health system resources, and it is very important to understand its capacity to provide integrated TB-HIV services. Objective: This study aims to assess …
Roza Kurniati, Dwitya Elvira, Rido Wandrivel
…ckground: Tuberculosis is the most common cause of death in HIV patients. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that plays a crucial role in the immune response to TB and HIV infection. Increased plasma IDO1 activity in TB patients can be a promising marker for the di…
Human Sciences Research Council
…ing intersecting epidemics of human immunodeficiency virus (HIV) and tuberculosis (TB). Among people living with HIV, TB is the predominant cause of death. Since 2002, South Africa has conducted six national population-based HIV surveys, and its first national TB prevalence surve…
Kalyan M, Sharma S, Kaur P, Sharma A, Verma I
Diagnosis of TB at early stages of HIV infection may lead to timely intervention for improving patient outcome. Antibodies to Mycobacterium tuberculosis recombinant RpfB protein and two immunodominant peptides of Rpf B protein were evaluated in the sera of HIV + TB + , HIV + and …
Assebe LF, Negussie EK, Jbaily A, Tolla MTT, Johansson KA
Objectives HIV and tuberculosis (TB) are major global health threats and can result in household financial hardships. Here, we aim to estimate the household economic burden and the incidence of catastrophic health expenditures (CHE) incurred by HIV and TB care across income quint…
Verma S, Du P, Nakanjako D, Hermans S, Briggs J, et al.
…s the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging particularly when HIV infection is advanced. Several gene signatures and serum protein biomarkers have been identified that distinguish activ…