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Salman Khan, Nadeem ur Rehman, Mohammad Zubair, Nisar Khan
Abstract Background: Multidrug-resistant tuberculosis (MDRTB) is a growing global health concern that is a chronic danger to world health due to tuberculosis (TB). Objective: The aim of this study was to examine the frequency of both pre extensively drug-resistant tuberculosis (P…
Dipali Maganbhai Gavali, Binita Aring, Hiral Gadhavi, Akhlakahemad Nathamehta, Abhishek B Dave, et al.
… high prevalence in India, accounting for one-fourth of the Tuberculosis (TB) cases in the world. In our study, we aimed to find the prevalence of Pre XDR-TB and XDR-TB amongst newly diagnosed cases of pulmonary MDR-TB who had never been previously treated with second-line drugs.…
Rim Abbas, Ali Salami, Ghassan Ghssein
Tuberculosis (TB) is an infectious disease caused by bacteria that primarily target the lungs. The transmission of this disease occurs through the air in the form of droplet nuclei. Unfortunately, there has been an emergence of resistance to strains of such infections, such as mu…
Eskild Petersen, Martin Rao, Giuseppe Ippolito, Gina Gualano, Jeremiah Chakaya, et al.
Tuberculosis today remains the world's number one cause of death from an infectious disease (WHO, 2018aWHO World Health Organization. Global tuberculosis report.2018Google Scholar). According to data from the World Health Organization Global Tuberculosis Report (WHO, 2018aWHO Wor…
Bashir Ullah, Rukhsana Saboor, Muhammad Zahid Iqbal, Atiq Ahmad Bhatti, Abad Ur Rehman, et al.
…o determine the frequency of pre-extensively drug resistant tuberculosis, extensively drug resistant tuberculosis in patients with multi-drug resistant tuberculosis. Study design: Retrospective/observational Place and duration of study: Department of Medicine, Bolan Medical Colle…
О.С. Шевченко, L.D. Todoriko, R.S. Shevchenko, S.L. Matvyeyeva, І.А. Овчаренко, et al.
…s well as the treatment regimens in patients with pulmonary tuberculosis. Materials and methods. This study included 100 patients with pulmonary tuberculosis, divided into two groups: Group 1 (n = 52) with drug-susceptible tuberculosis and Group 2 (n = 48) with drug-resistant tub…
KevisetuoAnthony Dzeyie, Saurav Basu, Tanzin Dikid
Introduction: A tuberculosis patient infects several healthy people prior to the diagnosis and initiation of treatment. Indiscriminate spitting in the community has been identified as a challenge to the prevention of tuberculosis; however, knowledge is still limited in terms of a…
Sadhana Awasthi, Neha Verma, Ram Gopal Nautiyal, Hariom Kumar Solanki
Background: Drug Resistant Tuberculosis (DR-TB) has frequently been encountered in India, and its presence has been known virtually from the time anti-TB drugs were introduced for the treatment of Tuberculosis. Multi Drug Resistant Tuberculosis (MDR-TB) is a man-made phenomenon a…
Dr.Talha Bin Liaquat Dr.Khursheed Alam
…trong><em>Background- </em></strong><em>Before diagnosis of tuberculosis in a patients and initiation of treatment, the infected person can infect some healthy people. In order to prevent the tuberculosis </em><em>undiscerning spitting is </em><em>like a challenge, as there is ve…
Aijaz Nabi Puttoo, Sandeep Tripathi, Naveed Nazir Shah, Ruqeya Nazir, Haamid Bashir, et al.
Drug-resistant tuberculosis (DR-TB) strains are a significant threat to global TB control. Due to a lack of resources and inadequate healthcare infrastructure, it is difficult to identify and monitor drug resistance situations in low and middle-income nations. The study aimed to …
Sondos A. A. Ibnouf, Fatma Esenkaya Taşbent
Background/Aim: Tuberculosis remains a major global health problem with a high morbidity and mortality rate, approximately a quarter of the population is infected with tuberculosis. Drug susceptibility testing is an essential tool for identifying and managing drug-resistant tuber…
А. Yu. Savchenko, В. Г. Кукес, М. S. Burenkov, G. V. Rаmenskаya
… The increase in the number of cases of multidrug-resistant tuberculosis (MDR-TB) determines the relevance of the development of new anti-TB drugs (ATDs). Determining the pharmacokinetics of a drug in the context of MDR-TB therapy is an integral part of the study of the original …
Bitrus Joshua Barde, Joseph Okopi, Isiyaku Ahmadu
Tuberculosis (TB) has afflicted humans for millennia and continues to pose a significant threat to public health worldwide. The World Health Organization classified TB as one of the top 10 causes of death globally, with approximately 10 million new cases and 1.4 million TB associ…
Л. В. Домотенко, T. P. Morozova, Mykyta Khramov, А. П. Шепелин
…te the commercial XDR test for susceptibility testing of M. tuberculosis to second line anti-tuberculosis drugs in clinical trials and as part of annual professional testing cycles coordinated by the World Health Organization (WHO). Subjects and Methods. Cultures of M. tuberculos…
Igor Mokrousov, Anna Vyazovaya, Gulnora Akhmedova, Elena Fundovnaya, E. S. Kozlova, et al.
…nt (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains requires use of novel compounds. New drugs require long-term treatment regimen and, consequently, long-term drug selective pressure gives more time to mycobacteria to develop resistance. At the same …
Lankamo Ena Digesa, Aklil Hailu Beyene, Erdaw Tachbele Betre
…ld>Background:</bold> The emergence of multi-drug resistant tuberculosis (MDR-TB) is a challenge for global prevention and control of the disease. MDR-TB case management is difficult because it exposes to further economic and social costs that the patients face while seeking help…
Kasimu Mamuda, Aliyu Sani, Steven Olonitola, Opaluwa Saraja
Background: Tuberculosis (TB) is one of the leading infectious diseases that cause death worldwide; the emergence of drug resistant mycobacterium tuberculosis is of great concern for TB control programme in Nigeria. Aim and objective: To detect multi-drug and extensively drug res…
Gizachew Taddesse Akalu, Belay Tessema, Waganeh Sinshaw, Misikir Amare, Getu Diriba, et al.
…ntional wisdom wrongly holds that the microbiological of M. tuberculosis complex in clinical specimens via culture and phenotypic drug susceptibility testing allows people to be correctly diagnosed and ensures an effective treatment regimen to be selected. This study was aimed to…
Anjali Yadav, Suman Singh, Rakesh Sharma, Santosh Kumar, Ajay Vir Singh, et al.
…tance and risk factorsfor extensively drug-resistance (XDR)-tuberculosis among multi-drug resistant (MDR)-tuberculosis patients from Agra region of Uttar Pradesh, North India.A total of 279 MDR-Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients of Agra regio…
Suphanat Wongsanuphat, Charuttaporn Jitpeera, Orathai Suwanchairob, Wannisa Theprongthong, Patcharin Tantiworrawit, et al.
…DoE) was notified of a confirmed extensively drug-resistant tuberculosis (XDR-TB) case in Bangkok. The DoE and local teams conducted a joint investigation to describe the epidemiological characteristics of the case, identify possible source cases and contacts, and implement contr…
Anita Kumari, Parveen Sharma, Rekha Bansal
…ercular drugs and may result in to extensive drug resistant tuberculosis (XDR-TB) and major challenges for successful outcome. Objective was to study treatment outcome of multi-drug resistant tuberculosis patients on second line anti-tuberculosis drugs at tertiary care hospital a…
DK Khadka, DS Bam, Prakash Ghimire, Amit Kumar Singh
Introduction: Tuberculosis is still one of the major public health problems in Nepal and multi drug resistant and extensively drug resistant tuberculosis (MDR /XDRTB) additionally has become serious issue. Prompt diagnosis and effective treatment of MDR/XDRTB is urgently needed. …
Alfonso J. Rodríguez‐Morales, Aula Abbara, Francine Ntoumi, Nathan Kapata, Peter Mwaba, et al.
World Tuberculosis (TB) Day, March 24th, 2023, will commemorate the day in 1882 when Professor Robert Koch announced his discovery of Mycobacterium tuberculosis (Mtb) when TB ravaged Europe. Over a century later, in 1993, the World Health Organization (WHO) declared TB a global h…
Elena Ufimtseva, Natalya Eremeeva, Diana Vakhrusheva, Sergey Skornyakov
Tuberculosis (TB) is a significant global health threat, with one-third of the world’s population infected with causative agent <i>M. tuberculosis</i> (<i>Mtb</i>). With the increasing prevalence of multidrug and extensively drug resistant (MDR and XDR) TB, there is a need to stu…
Tuelo Mogashoa, Lucy Mupfumi, Thato Iketleng, Pinkie Melamu, Nametso Kelentse, et al.
…nt (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis (Mtb) strains is a serious threat to tuberculosis control in Botswana. Early detection of drug-resistant isolates is critical to ensure optimal treatment and thereby improve treatment outcomes. The objective…