Showing 26–50 of 67 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
World Health Organization
World Health Organization
World Health Organization
…eatment and care of people with tuberculosis, covering both drug-susceptible and drug-resistant forms of the disease. It forms part of a consolidated series that integrates current WHO guidance into a coherent framework to support national tuberculosis programmes and health syste…
World Health Organization
…c methods for pulmonary and extrapulmonary tuberculosis and drug resistance detection. It covers low-, moderate- and high-complexity diagnostic platforms, including automated and manual NAATs, line probe assays and targeted next-generation sequencing. The annex summarizes eviden…
World Health Organization
…3: Diagnosis, provides technical guidance for culture-based drug susceptibility testing (DST) of anti-tuberculosis drugs used in the treatment of tuberculosis. The manual describes standardized phenotypic DST methods using solid and liquid culture media, including Löwenstein–Jens…
World Health Organization
… handbook consolidates operational guidance on treatment of drug-susceptible TB, treatment of drug-resistant TB, and tuberculosis care and support, complementing the WHO consolidated guidelines on tuberculosis. Intended for national tuberculosis programmes, policy-makers, clinici…
World Health Organization
…mmendations on diagnostic technologies for tuberculosis and drug-resistant tuberculosis. The publication presents systematic reviews, meta-analyses, qualitative evidence syntheses and economic evaluations examining the diagnostic accuracy, safety, cost–effectiveness and implement…
World Health Organization
…he diagnosis of tuberculosis (TB) infection, TB disease and drug-resistant TB. The publication responds to the continuing global burden of TB and the need for rapid, accurate and accessible diagnostic approaches to support early detection, treatment initiation and prevention effo…
World Health Organization
…n critical concentrations for pretomanid and cycloserine in drug susceptibility testing for tuberculosis. The document examines available microbiological, pharmacokinetic and pharmacodynamic evidence related to these medicines, with particular emphasis on minimum inhibitory conce…
World Health Organization
…e use of rapid diagnostic technologies for tuberculosis and drug-resistant tuberculosis. It summarizes the assessment processes used by guideline development groups, including considerations related to diagnostic accuracy, desirable and undesirable effects, certainty of evidence,…
World Health Organization
… diagnostic technologies used in tuberculosis detection and drug-resistance testing. The document supports the evidence-to-decision process underlying WHO recommendations by summarizing the certainty of evidence, diagnostic accuracy and clinical impact of multiple assays across d…
World Health Organization
… on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The publication describes WHO-recommended diagnostic tests and testing algorithms for the detection of Mycobacterium tuberculosis complex and resistance to anti-TB medicines, includin…
World Health Organization
…ated diagnostic technologies for tuberculosis infection and drug-resistant tuberculosis. The document presents the methods, findings and policy considerations from Pathway B evaluations of interferon-gamma release assays (IGRAs) for detection of TB infection and targeted next gen…
World Health Organization
…ing commercial flights, particularly in the context of multidrug-resistant and extensively drug-resistant forms of the disease. Developed as a revised third edition in response to evolving epidemiological and regulatory challenges, these guidelines examine the available evidence …
World Health Organization
…dations on the diagnosis of tuberculosis (TB), detection of drug-resistant TB and testing for TB infection. The publication consolidates, for the first time, operational guidance previously issued separately for TB diagnosis and TB infection testing, and aligns implementation adv…
World Health Organization. Regional Office for Europe
…sults required for the efficient and effective treatment of drug-resistant TB comprising both phenotypic and genotypic methods.
World Health Organization
…t of critical concentrations for pretomanid and cycloserine drug susceptibility testing in tuberculosis (TB). The document addresses a major gap in the laboratory diagnosis and management of drug-resistant TB, given the increasing use of pretomanid-containing regimens and the abs…
World Health Organization
… on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The publication describes WHO-recommended diagnostic tests for the detection of Mycobacterium tuberculosis complex and resistance to anti-TB medicines, including molecular rapid diagn…
World Health Organization
…pid diagnostic technologies for tuberculosis and rifampicin resistance detection. It supports transparency in the guideline development process by documenting the evidence base used for evaluating diagnostic accuracy, clinical impact and implementation considerations across diffe…
World Health Organization
…tic technologies for the detection of tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The document describes the operational characteristics, testing procedures, equipment requirements, storage conditions, throughput, connectivity options and implementation considerati…
World Health Organization
…tic technologies for the detection of tuberculosis (TB) and drug-resistant TB. Developed within the framework of the WHO End TB Strategy and global commitments adopted at the 2018 United Nations high-level meeting on TB, the document supports efforts to improve early diagnosis an…
World Health Organization
…tic technologies for the detection of tuberculosis (TB) and drug-resistant TB. Developed within the framework of the WHO End TB Strategy and global commitments adopted at the 2018 United Nations high-level meeting on TB, the document supports efforts to improve early diagnosis, i…
World Health Organization
… on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant TB detection. The publication compiles systematic reviews, meta-analyses, qualitative evidence syntheses and economic evaluations assessing the diagnostic accuracy, clinical impact, feasibility and user pe…
Jakubowiak, Wiesław, Korzeniewska-Koseła, Maria, Kuś, Jan, Michałowska-Mitczuk, Dorota, Wesołowski, Stefan, et al.
…such as the adverse effects of treatment, the management of drug-resistant tuberculosis and the combination of TB/HIV. Finally, the management of tuberculosis in groups at risk and health education are discussed. It is expected that this manual will be of help to all NTPs which a…
WHO Global Tuberculosis Programme