TB Research

Indeterminant Interferon-γ Release Assays in Refugee Children with Splenomegaly, Uganda, 2020-2023.

Christina R Phares, Moses Mwesigwa, Sean R Toney

Emerging infectious diseases · 2026-03

Abstract

We observed a novel association between splenomegaly and indeterminate interferon-γ release assays in refugee children 5-14 years of age in Uganda. Those demonstrating splenomegaly were 4 times more likely to have indeterminate results. Among refugee children 2-4 years of age, >10% had indeterminate results even without splenomegaly.

MeSH terms

  • Humans
  • Uganda
  • Refugees
  • Child
  • Child, Preschool
  • Splenomegaly
  • Adolescent
  • Female
  • Male
  • Interferon-gamma Release Tests
  • Interferon-gamma