Family Support and Medication Adherence to Anti-Tuberculosis Drug Therapy: A Cross-Sectional Study
Nonok Karlina, Astri Mardiani, Yani Kamasturyani, Uni Wahyuni, Vivi Leona Amelia
Journal of Integrated Health Research · 2025-04
Abstract
Introduction: Tuberculosis (TB) continues to pose a significant public health challenge worldwide, particularly in high-burden countries like Indonesia. Medication adherence is critical for the success of TB drug therapy, yet non-adherence remains a major obstacle to disease control. Family support has been recognized as a key factor in improving adherence to tuberculosis drug therapy. This study investigates the relationship between family support and medication adherence among TB patients in the Talun Health Center working area. Objective: This study aims to analyze the association between family support and adherence to tuberculosis drug therapy. Methods: A cross-sectional study was conducted involving 42 TB patients selected through total sampling. Data collection utilized a validated family support questionnaire and the Medication Adherence Report Scale-10 (MARS-10) to assess adherence levels. The Spearman Rank correlation test was applied for statistical analysis. Results: The findings revealed that 83.3% of TB patients received strong family support, while 16.7% experienced insufficient support. Among those with strong family support, 83.3% demonstrated adherence to tuberculosis drug therapy, whereas 16.7% did not. Statistical analysis indicated a significant positive correlation between family support and medication adherence (p < 0.001). Conclusion: The study highlights the crucial role of family support in enhancing medication adherence in tuberculosis drug therapy. Implications: Healthcare professionals should integrate family-centered approaches in TB management and develop targeted interventions to strengthen family involvement. Further research with a larger sample size and diverse settings is recommended to explore additional determinants of adherence.
MeSH terms
- Cross-sectional study
- Medication adherence
- Medicine
- Tuberculosis
- Directly Observed Therapy
- Drug
- Pharmacotherapy
- Family medicine