TB Research

Milky heart: A rare case of tuberculous chylopericardium managed conservatively

Enriquez KPD, Pilapil JCA, Go BS, Gavino RLC, Pipo MM, Punzalan FER

Asian cardiovascular & thoracic annals · 2025-03

Abstract

IntroductionTuberculosis (TB) is a rare cause of chylopericardium. Optimal management remains unclear.Methods/ResultsA 30-year-old Filipino male presented with recurrent massive pericardial effusions, with pericardiostomy revealing chylopericardium. Microbiologic TB studies were negative, and other etiologies were excluded. Pericardial fluid adenosine deaminase was elevated; anti-TB regimen was initiated, leading to resolution.DiscussionThere is no consensus about the optimal management of TB chylopericardium. Adenosine deaminase represents a useful test to diagnose TB in inflammatory, lymphocyte-predominant effusions, especially when other tests are negative. Failed conservative management merits more invasive approaches.ConclusionWhile data remain lacking, this case suggests that TB chylopericardium responds to anti-TB therapy.

MeSH terms

  • Humans
  • Pericarditis, Tuberculous
  • Pericardial Effusion
  • Recurrence
  • Adenosine Deaminase
  • Antitubercular Agents
  • Pericardiocentesis
  • Treatment Outcome
  • Pericardiectomy
  • Adult
  • Male
  • Biomarkers
  • Pericardial Fluid
  • Conservative Treatment