TB Research

TREATMENT OF ACTIVE AND LATENT MULTIDRUG-RESISTANT TUBERCULOSIS IN CHILDREN OF THE SAME FAMILY

Е. И. Никишова, T. I. Guryeva, Natalia Vlasova, A.A. Markova, Z.E. Jafarova, А. O. Мaryandyshev

Tuberkulez i socialʹno značimye zabolevaniâ · 2024-01

Abstract

An observation of the management of active and latent tuberculosis with multidrug resistance of the causative agent of the disease in children from the same family has been presented. The efficacy and safety of a short, fully oral chemotherapy regimen with the use of new and repurposed drugs in a child with active pulmonary tuberculosis has been demonstrated. During the preventive treatment of latent tuberculosis infection for six months no adverse reactions after taking levofloxacin were reported. In one case, preventive treatment of latent MDR-TB was not carried out due to co-pathology newly diagnosed before taking the drug.

MeSH terms

  • Latent tuberculosis
  • Medicine
  • Tuberculosis
  • Levofloxacin
  • Active tuberculosis
  • Multiple drug resistance
  • Regimen
  • Adverse effect
  • Adverse drug reaction
  • Drug resistance
  • Pediatrics
  • Drug
  • Intensive care medicine