TB Research

Delayed sternal <i>Mycobacterium tuberculosis</i> infection after left ventricular assist device implantation: A case report

Zhihua Wang, Junlong Hu, Zeyuan Zhao, Junjie Sun, Jianchao Li, Xiaoliang Qian, Zhaoyun Cheng

The International Journal of Artificial Organs · 2024-02

Abstract

(Mtb) infection in patients with mechanical circulatory support devices is extremely rare. We present a case involving a 38-year-old male who experienced a delayed sternal Mtb infection following left ventricular assist device (LVAD) implantation. More than 5 months post-surgery, the patient was readmitted to the hospital presenting a subxiphoid abscess. The incision site displayed an unsatisfactory healing process after the incision and drainage of the abscess. Despite engaging in a rigorous treatment protocol, which included anti-infective therapy, vacuum-assisted closure, and surgical debridement, the patient's wound remained unhealed. Ultimately, after pus gene sequencing confirmed the diagnosis, the patient was administered a regimen combining anti-tuberculosis and anti-infective therapy, which culminated in the successful healing of the wound. This singular case study not only reveals the clinical progression of an unexpected Mtb infection post-implantation but also emphasizes the challenges encountered in diagnosis and management.

MeSH terms

  • Medicine
  • Surgery
  • Tuberculosis
  • Abscess
  • Regimen
  • Debridement (dental)
  • Mycobacterium tuberculosis
  • Cardiac surgery