TB Research

US Guidelines Fall Short on Short-Course Tuberculosis-Preventive Therapy

Krishnan S, Chaisson RE

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024-03

Abstract

The provision of tuberculosis-preventive therapy (TPT) to vulnerable populations is critical for global control. Shorter-course TPT regimens are highly effective and improve completion rates. Despite incorporation of 1 month of rifapentine and isoniazid into global guidelines, current US TPT guidelines do not include this as a recommended regimen, but should.

MeSH terms

  • Humans
  • Tuberculosis
  • Isoniazid
  • Antitubercular Agents
  • Antibiotic Prophylaxis
  • Drug Therapy, Combination
  • Latent Tuberculosis