TB Research

Use of Nanotechnology to Mitigate Tuberculosis

Tayyaba Akhtar, Muhammad Naeem, Muhammad Younus, Un Qamar, Waqas Nisa, Hafiz Farooq, Nida Aslam, Maria Wazir, et al. (68 authors)

International Journal of Agriculture and Biosciences · 2023-01

Abstract

Tuberculosis is a disastrous malady spreading exponentially throughout the world.TB has been long identified as a threat to global health by several international bodies but this threat was amplified upon the identification of multi-drug-resistant germs of TB.Such a scenario arose from several factors regarding TB.Some important factors in this aspect include lack of awareness as TB is prevalent in low-income, loweducation countries and exhaustive treatment regimens for TB.Similarly, the adverse effects of drugs are also a factor leading to hampering proper dose implementation.Liver damage caused by anti-TB drugs often leads to a pause in TB medication in turn contributing to increased antibiotic resistance to etiologic agents of TB.Such problems can be easily overcome by developing antibiotic alternatives that can battle antibiotic resistance while reducing the length and adverse effects of the TB medication.Such an option regarding antibiotic alternatives is the use of nanotechnology and nanomaterials.These substances can help us battle anti-microbial resistance by bypassing the defense mechanism of TB bacteria while simultaneously preventing side effects of the drugs through reduced doses.

MeSH terms

  • Tuberculosis
  • Nanotechnology
  • Biotechnology