Study of the Role of Vitamin (D) Deficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Background; COPD is a variety of lung symptoms that are characterized by persistent, frequently worsening airflow restriction and chronic respiratory symptoms (dyspnea, cough, and formation of sputum) owing to diseases in the bronchial tree (bronchiolitis, bronchitis), or/and alveoli (emphysema), objectives; to research the impact of vitamin (D) deficiency in individuals with stable and acute exacerbation COPD, Subjects and methods; This case control study was carried out at Al- Azhar University Hospital-Assuit between February 2022 and December 2022 on (100) COPD patients and another (50) control group of individuals who looked to be in good health. Result; Moreover, Levels of vitamin (D) were markedly high in controls compared to Stable COPD group and levels of vitamin D were relatively high in Stable COPD compared to AECOPD group, Conclusion; AECOPD patients were shown to have vitamin D insufficiency and vitamin D insufficiency was strongly related to severity of COPD. Vitamin D insufficiency was also related to illness exacerbation.